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1
The N terminus of cGAS de‐oligomerizes the cGAS:DNA complex and lifts the DNA size restriction of core‐cGAS activity
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The N terminus of cGAS de‐oligomerizes the cGAS:DNA complex and lifts the DNA size restriction of core‐cGAS activity

FEBS letters, 2017-03, Vol.591 (6), p.954-961 [Peer Reviewed Journal]

2017 Federation of European Biochemical Societies ;2017 Federation of European Biochemical Societies. ;ISSN: 0014-5793 ;EISSN: 1873-3468 ;DOI: 10.1002/1873-3468.12598 ;PMID: 28214358

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2
SnapShot: CGAS-STING Signaling
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SnapShot: CGAS-STING Signaling

Cell, 2018-03, Vol.173 (1), p.276-276.e1 [Peer Reviewed Journal]

2018 Elsevier Inc. ;Copyright © 2018 Elsevier Inc. All rights reserved. ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2018.03.015 ;PMID: 29570996

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3
Structural mechanism of cGAS inhibition by the nucleosome
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Structural mechanism of cGAS inhibition by the nucleosome

Nature (London), 2020-11, Vol.587 (7835), p.668-672 [Peer Reviewed Journal]

COPYRIGHT 2020 Nature Publishing Group ;Copyright Nature Publishing Group Nov 26, 2020 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-020-2750-6 ;PMID: 32911482

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4
Molecular mechanisms and cellular functions of cGAS-STING signalling
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Molecular mechanisms and cellular functions of cGAS-STING signalling

Nature reviews. Molecular cell biology, 2020-09, Vol.21 (9), p.501-521 [Peer Reviewed Journal]

COPYRIGHT 2020 Nature Publishing Group ;Springer Nature Limited 2020. ;ISSN: 1471-0072 ;EISSN: 1471-0080 ;DOI: 10.1038/s41580-020-0244-x ;PMID: 32424334

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5
cGAS–STING signaling
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cGAS–STING signaling

Current biology, 2022-07, Vol.32 (13), p.R730-R734 [Peer Reviewed Journal]

2022 Elsevier Inc. ;ISSN: 0960-9822 ;EISSN: 1879-0445 ;DOI: 10.1016/j.cub.2022.05.027

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6
cGAS is essential for cellular senescence
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cGAS is essential for cellular senescence

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (23), p.E4612-E4620 [Peer Reviewed Journal]

Volumes 1–89 and 106–114, copyright as a collective work only; author(s) retains copyright to individual articles ;Copyright National Academy of Sciences Jun 6, 2017 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1705499114 ;PMID: 28533362

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7
The N terminus of cGAS de‐oligomerizes the cGAS:DNA complex and lifts the DNA size restriction of core‐cGAS activity
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Article
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The N terminus of cGAS de‐oligomerizes the cGAS:DNA complex and lifts the DNA size restriction of core‐cGAS activity

FEBS letters, 2018-02, Vol.592 (4), p.656-656 [Peer Reviewed Journal]

2018 Federation of European Biochemical Societies ;ISSN: 0014-5793 ;EISSN: 1873-3468 ;DOI: 10.1002/1873-3468.13007 ;PMID: 29485700

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8
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis
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Cytosolic RNA:DNA hybrids activate the cGAS-STING axis

The EMBO journal, 2014-12, Vol.33 (24), p.2937-2946 [Peer Reviewed Journal]

2014 The Authors ;2014 The Authors. ;2014 The Authors 2014 ;ISSN: 0261-4189 ;EISSN: 1460-2075 ;DOI: 10.15252/embj.201488726 ;PMID: 25425575 ;CODEN: EMJODG

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9
The Cytosolic DNA-Sensing cGAS-STING Pathway in Cancer
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The Cytosolic DNA-Sensing cGAS-STING Pathway in Cancer

Cancer discovery, 2020-01, Vol.10 (1), p.26-39

2019 American Association for Cancer Research. ;ISSN: 2159-8274 ;EISSN: 2159-8290 ;DOI: 10.1158/2159-8290.cd-19-0761 ;PMID: 31852718

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10
cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING
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cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING

Nature (London), 2013-06, Vol.498 (7454), p.380-384 [Peer Reviewed Journal]

Copyright Nature Publishing Group Jun 20, 2013 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature12306 ;PMID: 23722158 ;CODEN: NATUAS

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11
The cGAS-STING pathway as a therapeutic target in inflammatory diseases
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The cGAS-STING pathway as a therapeutic target in inflammatory diseases

Nature reviews. Immunology, 2021-09, Vol.21 (9), p.548-569 [Peer Reviewed Journal]

2021. Springer Nature Limited. ;COPYRIGHT 2021 Nature Publishing Group ;Springer Nature Limited 2021. ;Springer Nature Limited 2021 ;ISSN: 1474-1733 ;EISSN: 1474-1741 ;DOI: 10.1038/s41577-021-00524-z ;PMID: 33833439

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12
Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling
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Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling

Nature (London), 2019-02, Vol.566 (7743), p.259-263 [Peer Reviewed Journal]

COPYRIGHT 2019 Nature Publishing Group ;Copyright Nature Publishing Group Feb 14, 2019 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-019-0928-6 ;PMID: 30728498

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13
DNA sensing by the cGAS-STING pathway in health and disease
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DNA sensing by the cGAS-STING pathway in health and disease

Nature reviews. Genetics, 2019-11, Vol.20 (11), p.657-674 [Peer Reviewed Journal]

COPYRIGHT 2019 Nature Publishing Group ;COPYRIGHT 2019 Nature Publishing Group ;Copyright Nature Publishing Group Nov 2019 ;Springer Nature Limited 2019. ;ISSN: 1471-0056 ;EISSN: 1471-0064 ;DOI: 10.1038/s41576-019-0151-1 ;PMID: 31358977

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14
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity
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cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity

The Journal of clinical investigation, 2019-11, Vol.130 (11), p.4850-4862 [Peer Reviewed Journal]

COPYRIGHT 2019 American Society for Clinical Investigation ;COPYRIGHT 2019 American Society for Clinical Investigation ;2019 American Society for Clinical Investigation 2019 American Society for Clinical Investigation ;ISSN: 0021-9738 ;EISSN: 1558-8238 ;DOI: 10.1172/jci127471 ;PMID: 31408442

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15
Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response
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Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response

The EMBO journal, 2016-04, Vol.35 (8), p.831-844 [Peer Reviewed Journal]

2016 The Authors. Published under the terms of the CC BY 4.0 license ;2016 The Authors. Published under the terms of the CC BY 4.0 license. ;ISSN: 0261-4189 ;EISSN: 1460-2075 ;DOI: 10.15252/embj.201593339 ;PMID: 26903602 ;CODEN: EMJODG

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16
cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers
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cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers

Nature (London), 2022-07, Vol.607 (7918), p.366-373 [Peer Reviewed Journal]

2022. The Author(s), under exclusive licence to Springer Nature Limited. ;Copyright Nature Publishing Group Jul 14, 2022 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-022-04847-2 ;PMID: 35705809

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17
NAD + supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer's disease via cGAS-STING
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NAD + supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer's disease via cGAS-STING

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (37) [Peer Reviewed Journal]

Copyright National Academy of Sciences Sep 14, 2021 ;2021 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.2011226118 ;PMID: 34497121

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18
The cGAS-STING pathway drives type I IFN immunopathology in COVID-19
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The cGAS-STING pathway drives type I IFN immunopathology in COVID-19

Nature (London), 2022-03, Vol.603 (7899), p.145-151 [Peer Reviewed Journal]

2022. The Author(s). ;Copyright Nature Publishing Group Mar 3, 2022 ;The Author(s) 2022 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-022-04421-w ;PMID: 35045565

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19
Listerin promotes cGAS protein degradation through the ESCRT pathway to negatively regulate cGAS-mediated immune response
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Listerin promotes cGAS protein degradation through the ESCRT pathway to negatively regulate cGAS-mediated immune response

Proceedings of the National Academy of Sciences - PNAS, 2023-12, Vol.120 (52), p.e2308853120-e2308853120 [Peer Reviewed Journal]

Copyright National Academy of Sciences Dec 26, 2023 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.2308853120 ;PMID: 38109536

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20
cGAS-STING pathway in cancer biotherapy
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cGAS-STING pathway in cancer biotherapy

Molecular cancer, 2020-09, Vol.19 (1), p.1-136, Article 136 [Peer Reviewed Journal]

COPYRIGHT 2020 BioMed Central Ltd. ;2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2020 ;ISSN: 1476-4598 ;EISSN: 1476-4598 ;DOI: 10.1186/s12943-020-01247-w ;PMID: 32887628

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