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1
Limbic Predominant Age-Related TDP-43 Encephalopathy (LATE): Clinical and Neuropathological Associations
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Limbic Predominant Age-Related TDP-43 Encephalopathy (LATE): Clinical and Neuropathological Associations

Journal of neuropathology and experimental neurology, 2020-03, Vol.79 (3), p.305-313 [Peer Reviewed Journal]

2019 American Association of Neuropathologists, Inc. All rights reserved. 2019 ;2020 by American Association of Neuropathologists, Inc. ;2019 American Association of Neuropathologists, Inc. All rights reserved. ;COPYRIGHT 2020 Oxford University Press ;ISSN: 0022-3069 ;EISSN: 1554-6578 ;DOI: 10.1093/jnen/nlz126 ;PMID: 31845964

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2
Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease
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Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease

Acta neuropathologica, 2022-01, Vol.143 (1), p.15-31 [Peer Reviewed Journal]

The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021 ;2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. ;COPYRIGHT 2022 Springer ;The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021. ;ISSN: 0001-6322 ;EISSN: 1432-0533 ;DOI: 10.1007/s00401-021-02383-3 ;PMID: 34854996

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3
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency
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Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Nature (London), 2020-12, Vol.588 (7838), p.459-465 [Peer Reviewed Journal]

COPYRIGHT 2020 Nature Publishing Group ;Copyright Nature Publishing Group Dec 17, 2020 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-020-2709-7 ;PMID: 32866962

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4
RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy
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RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy

Brain (London, England : 1878), 2019-12, Vol.142 (12), p.3753-3770 [Peer Reviewed Journal]

The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. ;The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. 2019 ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awz313 ;PMID: 31605140

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5
Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion
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Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion

The Journal of biological chemistry, 2013-07, Vol.288 (27), p.19614-19624 [Peer Reviewed Journal]

2013 © 2013 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2013 by The American Society for Biochemistry and Molecular Biology, Inc. 2013 ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M113.463828 ;PMID: 23689371

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6
Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease
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Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease

Brain (London, England : 1878), 2017-12, Vol.140 (12), p.3081-3104 [Peer Reviewed Journal]

The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awx198 ;PMID: 29053785

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7
TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy
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TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy

Journal of neuropathology and experimental neurology, 2010-09, Vol.69 (9), p.918-929 [Peer Reviewed Journal]

2010 American Association of Neuropathologists, Inc ;ISSN: 0022-3069 ;EISSN: 1554-6578 ;DOI: 10.1097/NEN.0b013e3181ee7d85 ;PMID: 20720505 ;CODEN: JNENAD

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8
Homozygous GRN mutations: new phenotypes and new insights into pathological and molecular mechanisms
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Homozygous GRN mutations: new phenotypes and new insights into pathological and molecular mechanisms

Brain (London, England : 1878), 2020-01, Vol.143 (1), p.303-319 [Peer Reviewed Journal]

The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For permissions, please email: journals.permissions@oup.com. ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awz377 ;PMID: 31855245

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9
Exosome secretion is a key pathway for clearance of pathological TDP-43
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Exosome secretion is a key pathway for clearance of pathological TDP-43

Brain (London, England : 1878), 2016-12, Vol.139 (Pt 12), p.3187-3201 [Peer Reviewed Journal]

The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ;The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2016 ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/aww237 ;PMID: 27679482

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10
Physiological functions and pathobiology of TDP‐43 and FUS/TLS proteins
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Physiological functions and pathobiology of TDP‐43 and FUS/TLS proteins

Journal of neurochemistry, 2016-08, Vol.138 (S1), p.95-111 [Peer Reviewed Journal]

2016 International Society for Neurochemistry ;2016 International Society for Neurochemistry. ;Copyright © 2016 International Society for Neurochemistry ;ISSN: 0022-3042 ;EISSN: 1471-4159 ;DOI: 10.1111/jnc.13625 ;PMID: 27015757

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11
Symptomatic Profile and Cognitive Performance in Autopsy-Confirmed Limbic-Predominant Age-Related TDP-43 Encephalopathy With Comorbid Alzheimer Disease
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Symptomatic Profile and Cognitive Performance in Autopsy-Confirmed Limbic-Predominant Age-Related TDP-43 Encephalopathy With Comorbid Alzheimer Disease

Journal of neuropathology and experimental neurology, 2022-12, Vol.81 (12), p.975-987 [Peer Reviewed Journal]

The Author(s) 2022. Published by Oxford University Press on behalf of American Association of Neuropathologists, Inc. All rights reserved. For permissions, please email: journals.permissions@oup.com 2022 ;The Author(s) 2022. Published by Oxford University Press on behalf of American Association of Neuropathologists, Inc. All rights reserved. For permissions, please email: journals.permissions@oup.com. ;COPYRIGHT 2022 Oxford University Press ;ISSN: 0022-3069 ;EISSN: 1554-6578 ;DOI: 10.1093/jnen/nlac093 ;PMID: 36264254

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12
Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy
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Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy

RNA biology, 2021-11, Vol.18 (11), p.1546-1554 [Peer Reviewed Journal]

2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2020 ;2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2020 The Author(s) ;ISSN: 1547-6286 ;EISSN: 1555-8584 ;DOI: 10.1080/15476286.2020.1860580 ;PMID: 33427561

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13
TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43
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TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43

Neurobiology of disease, 2024-04, Vol.193, p.106437-106437, Article 106437 [Peer Reviewed Journal]

2024 The Authors ;Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved. ;2024 The Authors 2024 ;ISSN: 0969-9961 ;EISSN: 1095-953X ;DOI: 10.1016/j.nbd.2024.106437 ;PMID: 38367882

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14
Metabolism and mis-metabolism of the neuropathological signature protein TDP-43
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Article
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Metabolism and mis-metabolism of the neuropathological signature protein TDP-43

Journal of cell science, 2014-07, Vol.127 (Pt 14), p.3024-3038 [Peer Reviewed Journal]

2014. Published by The Company of Biologists Ltd. ;ISSN: 0021-9533 ;EISSN: 1477-9137 ;DOI: 10.1242/jcs.136150 ;PMID: 24860144

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15
Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A
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Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A

Acta neuropathologica, 2015-01, Vol.129 (1), p.53-64 [Peer Reviewed Journal]

Springer-Verlag Berlin Heidelberg 2014 ;COPYRIGHT 2015 Springer ;Springer-Verlag Berlin Heidelberg 2015 ;ISSN: 0001-6322 ;EISSN: 1432-0533 ;DOI: 10.1007/s00401-014-1358-z ;PMID: 25367383

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16
Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins
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Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins

Nature communications, 2023-10, Vol.14 (1), p.6492-6492, Article 6492 [Peer Reviewed Journal]

2023. Springer Nature Limited. ;Springer Nature Limited 2023 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-023-42147-z ;PMID: 37838698

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17
Cortical influences drive amyotrophic lateral sclerosis
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Article
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Cortical influences drive amyotrophic lateral sclerosis

Journal of neurology, neurosurgery and psychiatry, 2017-11, Vol.88 (11), p.917-924 [Peer Reviewed Journal]

Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. ;Copyright: 2017 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. ;ISSN: 0022-3050 ;EISSN: 1468-330X ;DOI: 10.1136/jnnp-2017-315573 ;PMID: 28710326

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18
TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD
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TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD

Neurology, 2017-02, Vol.88 (7), p.653-660 [Peer Reviewed Journal]

2017 American Academy of Neurology ;2017 American Academy of Neurology. ;2017 American Academy of Neurology 2017 American Academy of Neurology ;ISSN: 0028-3878 ;EISSN: 1526-632X ;DOI: 10.1212/WNL.0000000000003610 ;PMID: 28087828

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19
Somatic TARDBP variants as a cause of semantic dementia
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Somatic TARDBP variants as a cause of semantic dementia

Brain (London, England : 1878), 2020-12, Vol.143 (12), p.3827-3841 [Peer Reviewed Journal]

The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain. ;The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain. 2020 ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awaa317 ;PMID: 33155043

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20
TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets
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TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

Neurotherapeutics, 2015-04, Vol.12 (2), p.352-363 [Peer Reviewed Journal]

The Author(s) 2015 ;The American Society for Experimental NeuroTherapeutics, Inc. 2015 ;ISSN: 1933-7213 ;ISSN: 1878-7479 ;EISSN: 1878-7479 ;DOI: 10.1007/s13311-015-0338-x ;PMID: 25652699

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