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1
Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3
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Article
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Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3

Nature (London), 2022-04, Vol.604 (7904), p.184-189 [Peer Reviewed Journal]

2022. The Author(s), under exclusive licence to Springer Nature Limited. ;Copyright Nature Publishing Group Apr 7, 2022 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-022-04467-w ;PMID: 35114687

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2
Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation
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Article
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Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation

Nature communications, 2021-11, Vol.12 (1), p.6607-15, Article 6607 [Peer Reviewed Journal]

2021. The Author(s). ;The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2021 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-021-26935-z ;PMID: 34785661

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3
Pyroptosis inhibiting nanobodies block Gasdermin D pore formation
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Article
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Pyroptosis inhibiting nanobodies block Gasdermin D pore formation

Nature communications, 2023-12, Vol.14 (1), p.7923-7923, Article 7923 [Peer Reviewed Journal]

The Author(s) 2023 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-023-43707-z ;PMID: 38040708

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4
Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter
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Article
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Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter

Nature communications, 2022-08, Vol.13 (1), p.4471-4471, Article 4471 [Peer Reviewed Journal]

2022. The Author(s). ;The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2022 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-022-31907-y ;PMID: 35927235

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5
Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus
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Article
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Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus

Journal of clinical immunology, 2022-02, Vol.42 (2), p.325-335 [Peer Reviewed Journal]

The Author(s) 2021 ;2021. The Author(s). ;The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 0271-9142 ;EISSN: 1573-2592 ;DOI: 10.1007/s10875-021-01175-4 ;PMID: 34783940

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6
Yeast proteins Gar1p, Nop1p, Npl3p, Nsr1p, and Rps2p are natively methylated and are substrates of the arginine methyltransferase Hmt1p
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Article
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Yeast proteins Gar1p, Nop1p, Npl3p, Nsr1p, and Rps2p are natively methylated and are substrates of the arginine methyltransferase Hmt1p

Proteomics (Weinheim), 2015-09, Vol.15 (18), p.3209-3218 [Peer Reviewed Journal]

2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim ;2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. ;ISSN: 1615-9853 ;EISSN: 1615-9861 ;DOI: 10.1002/pmic.201500075 ;PMID: 26081071

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7
The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation
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Article
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The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105501-105501, Article 105501 [Peer Reviewed Journal]

Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1016/j.jbc.2023.105501 ;PMID: 38016516

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8
Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain
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Article
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Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain

The Journal of biological chemistry, 2022-12, Vol.298 (12), p.102645-102645, Article 102645 [Peer Reviewed Journal]

2022 The Authors ;Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved. ;2022 The Authors 2022 ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1016/j.jbc.2022.102645 ;PMID: 36309085

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9
P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection
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Article
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P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

The Journal of experimental medicine, 2023-01, Vol.220 (1) [Peer Reviewed Journal]

2022 Jenster et al. ;2022 Jenster et al. 2022 Jenster et al. ;ISSN: 0022-1007 ;EISSN: 1540-9538 ;DOI: 10.1084/jem.20220837 ;PMID: 36315050

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10
Antiviral signalling by a cyclic nucleotide activated CRISPR protease
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Article
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Antiviral signalling by a cyclic nucleotide activated CRISPR protease

Nature (London), 2023-02, Vol.614 (7946), p.168-174 [Peer Reviewed Journal]

2022. The Author(s), under exclusive licence to Springer Nature Limited. ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-022-05571-7 ;PMID: 36423657

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11
Investigating the molecular basis of human NLRP1 inflammasome activation
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Thesises (postgraduate)
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Investigating the molecular basis of human NLRP1 inflammasome activation

Digital Resources/Online E-Resources

12
Investigating the molecular basis of human NLRP1 inflammasome activation
Material Type:
Thesises (postgraduate)
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Investigating the molecular basis of human NLRP1 inflammasome activation

Digital Resources/Online E-Resources

13
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
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Article
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TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

Cell, 2020-10, Vol.183 (3), p.636-649.e18 [Peer Reviewed Journal]

2020 The Author(s) ;Copyright © 2020 The Author(s). Published by Elsevier Inc. All rights reserved. ;2020 The Author(s) 2020 ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2020.09.020 ;PMID: 33031745

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14
Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules
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Article
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Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules

Antimicrobial agents and chemotherapy, 2014-07, Vol.58 (7), p.3666-3678 [Peer Reviewed Journal]

2015 INIST-CNRS ;Copyright © 2014, American Society for Microbiology. All Rights Reserved. ;Copyright © 2014, American Society for Microbiology. All Rights Reserved. 2014 American Society for Microbiology ;ISSN: 0066-4804 ;EISSN: 1098-6596 ;DOI: 10.1128/AAC.02721-13 ;PMID: 24733477 ;CODEN: AACHAX

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15
Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter
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Article
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Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter

cc_by ;DOI: 10.1038/s41467-022-31907-y

Digital Resources/Online E-Resources

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