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Levonorgestrel only emergency contraceptive use and risk of ectopic pregnancy in Eldoret Kenya: a case-control study

The Pan African medical journal, 2018, Vol.31 (214), p.214 [Peer Reviewed Journal]

Sahara Shurie et al. 2018. This work is published under http://creativecommons.org/licenses/by/2.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Sahara Shurie et al. 2018 ;ISSN: 1937-8688 ;EISSN: 1937-8688 ;DOI: 10.11604/pamj.2018.31.214.17484 ;PMID: 31447973

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Title:
Levonorgestrel only emergency contraceptive use and risk of ectopic pregnancy in Eldoret Kenya: a case-control study
Author: Shurie, Sahara ; Were, Edwin ; Orang'o, Omenge ; Keter, Alfred
Subjects: Adolescent ; Adult ; Age ; Birth control ; Case-Control Studies ; Confounding Factors, Epidemiologic ; Contraceptives, Postcoital - administration & dosage ; Contraceptives, Postcoital - adverse effects ; ectopic pregnancy ; Education ; Employment ; extra-uterine pregnancy ; Family planning ; Female ; Health sciences ; Humans ; Kenya ; levonorgestrel ; Levonorgestrel - administration & dosage ; Levonorgestrel - adverse effects ; Logistic Models ; postcoital contraception ; Pregnancy ; Pregnancy complications ; Pregnancy, Ectopic - epidemiology ; Pregnancy, Ectopic - etiology ; Reproductive health ; Risk Factors ; Surveys and Questionnaires ; Variables ; Womens health ; Young Adult
Is Part Of: The Pan African medical journal, 2018, Vol.31 (214), p.214
Description: ectopic pregnancy is one of the causes of maternal morbidity and mortality in sub-Saharan Africa. Levonorgestrel (LNG) only emergency contraceptive pill is a well-established emergency contraceptive pill that is administered within 72 hours after unprotected intercourse. This study aimed at determining whether or not there is a significant association between levonorgestrel emergency contraceptive use and the occurrence of ectopic pregnancy. case-control (1:3) study among 79 women with ectopic pregnancy (cases) matched against 237 women without (controls) at Moi Teaching and Referral Hospital in Eldoret, Kenya; Sociodemographic and clinical data were collected using a questionnaire. Association between ectopic pregnancy and LNG-EC was assessed using Pearson chi-square test. The relationship between outcome and exposure (while adjusting for confounders) was assessed using logistic regression model. The mean age was 27.15 years. Both cases and controls were similar by age (p = 0.990), educational level (p = 0.850), marital status (p = 0.559), employment status (p = 0.186) and parity (p = 0.999). Seventy-eight (24.7%) participants had a history of miscarriage. A higher proportion of the cases had history of using LNG-EC compared to the controls (32.9% vs. 7.2%, p < 0.001). The use of LNG-EC portended more than nine times increased odds of ectopic pregnancy compared to other contraceptive methods {OR = 9.34 (95% CI: 3.9 - 16.0)}. levonorgestrel only emergency contraceptive use was associated with ectopic pregnancy. One of the limitations of this study is that we could not control for all confounders of ectopic pregnancy.
Publisher: Uganda: African Field Epidemiology Network
Language: English
Identifier: ISSN: 1937-8688
EISSN: 1937-8688
DOI: 10.11604/pamj.2018.31.214.17484
PMID: 31447973
Source: Open Access: African Journals Online
PubMed Central (Open access)
DOAJ Directory of Open Access Journals
Geneva Foundation Free Medical Journals at publisher websites
AUTh Library subscriptions: ProQuest Central
MEDLINE
ROAD: Directory of Open Access Scholarly Resources

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Levonorgestrel only emergency contraceptive use and risk of ectopic pregnancy in Eldoret Kenya: a case-control study

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