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Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020

Euro surveillance : bulletin européen sur les maladies transmissibles, 2021-01, Vol.26 (1), p.1 [Peer Reviewed Journal]

Copyright Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS) Jan 7, 2021 ;This article is copyright of the authors or their affiliated institutions, 2021. 2021 The authors or their affiliated institutions ;ISSN: 1560-7917 ;ISSN: 1025-496X ;EISSN: 1560-7917 ;DOI: 10.2807/1560-7917.es.2020.26.1.2002106 ;PMID: 33413740

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Title:
Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020
Author: Leung, Kathy ; Shum, Marcus Hh ; Leung, Gabriel M ; Lam, Tommy Ty ; Wu, Joseph T
Subjects: Amino acids ; COVID-19 ; COVID-19 - diagnosis ; COVID-19 - epidemiology ; COVID-19 - transmission ; COVID-19 - virology ; Disease transmission ; Genetic Markers ; Genetic Variation ; Genome, Viral ; Humans ; Mutation ; Phylogeny ; Rapid Communication ; SARS-CoV-2 - genetics ; SARS-CoV-2 - pathogenicity ; Severe acute respiratory syndrome coronavirus 2 ; Spike Glycoprotein, Coronavirus - genetics ; United Kingdom - epidemiology
Is Part Of: Euro surveillance : bulletin européen sur les maladies transmissibles, 2021-01, Vol.26 (1), p.1
Description: Two new SARS-CoV-2 lineages with the N501Y mutation in the receptor-binding domain of the spike protein spread rapidly in the United Kingdom. We estimated that the earlier 501Y lineage without amino acid deletion Δ69/Δ70, circulating mainly between early September and mid-November, was 10% (6-13%) more transmissible than the 501N lineage, and the 501Y lineage with amino acid deletion Δ69/Δ70, circulating since late September, was 75% (70-80%) more transmissible than the 501N lineage.
Publisher: Sweden: Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS)
Language: English
Identifier: ISSN: 1560-7917
ISSN: 1025-496X
EISSN: 1560-7917
DOI: 10.2807/1560-7917.es.2020.26.1.2002106
PMID: 33413740
Source: Geneva Foundation Free Medical Journals at publisher websites
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Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020

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