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Most of the Intended Management Changes After 68Ga-DOTATATE PET/CT Are Implemented

The Journal of nuclear medicine (1978), 2017-11, Vol.58 (11), p.1793-1796 [Peer Reviewed Journal]

2017 by the Society of Nuclear Medicine and Molecular Imaging. 2017 ;ISSN: 0161-5505 ;EISSN: 1535-5667 ;DOI: 10.2967/jnumed.117.192450 ;PMID: 28473600

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  • Title:
    Most of the Intended Management Changes After 68Ga-DOTATATE PET/CT Are Implemented
  • Author: Calais, Jeremie ; Czernin, Johannes ; Eiber, Matthias ; Fendler, Wolfgang P ; Gartmann, Jeannine ; Heaney, Anthony P ; Hendifar, Andrew E ; Pisegna, Joseph R ; Hecht, J Randolph ; Wolin, Edward M ; Slavik, Roger ; Gupta, Pawan ; Quon, Andrew ; Schiepers, Christiaan ; Allen-Auerbach, Martin S ; Herrmann, Ken
  • Subjects: Theranostics
  • Is Part Of: The Journal of nuclear medicine (1978), 2017-11, Vol.58 (11), p.1793-1796
  • Description: In this prospective referring-physician–based survey, we investigated the definite clinical impact of 68 Ga-DOTATATE PET/CT on managing patients with neuroendocrine tumors (NETs). Methods: We prospectively studied 130 patients with 68 Ga-DOTATATE PET/CT referred for initial or subsequent management decisions (NCT02174679). Referring physicians completed one questionnaire before the scan (Q1) to indicate the treatment plan without PET/CT information, one immediately after review of the imaging report to denote intended management changes (Q2), and one 6 mo later (Q3) to verify whether intended changes were in fact implemented. To further validate the Q3 responses, a systematic electronic chart review was conducted. Results: All 3 questionnaires were completed by referring physicians for 96 of 130 patients (74%). 68 Ga-DOTATATE PET/CT resulted in intended management changes (Q2) in 48 of 96 patients (50%). These changes were finally implemented (Q3) in 36 of 48 patients (75%). Q3 responses were confirmed in all patients with an available electronic chart (36/96; 38%). Conclusion: This prospective study confirmed a significant impact of 68 Ga-DOTATATE PET/CT on the intended management of patients with NETs (50% of changes) and notably demonstrated a high implementation rate (75%) of these intended management changes.
  • Publisher: Society of Nuclear Medicine
  • Language: English
  • Identifier: ISSN: 0161-5505
    EISSN: 1535-5667
    DOI: 10.2967/jnumed.117.192450
    PMID: 28473600
  • Source: Alma/SFX Local Collection
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