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Neutrophil migration in infection and wound repair: going forward in reverse

Nature reviews. Immunology, 2016-06, Vol.16 (6), p.378-391 [Tạp chí có phản biện]

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Jun 2016 ;Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. 2016. ;ISSN: 1474-1733 ;EISSN: 1474-1741 ;DOI: 10.1038/nri.2016.49 ;PMID: 27231052

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Nhan đề:
Neutrophil migration in infection and wound repair: going forward in reverse
Tác giả: de Oliveira, Sofia ; Rosowski, Emily E ; Huttenlocher, Anna
Chủ đề: Animals ; Apoptosis ; Care and treatment ; Chemokines ; Chemotaxis, Leukocyte - drug effects ; Chemotaxis, Leukocyte - immunology ; Health aspects ; Humans ; Immune response ; Infections ; Infections - drug therapy ; Infections - immunology ; Infections - metabolism ; Infections - pathology ; Inflammation ; Inflammation - drug therapy ; Inflammation - immunology ; Inflammation - metabolism ; Inflammation - pathology ; Influence ; Leukocyte migration ; Leukocytes (neutrophilic) ; Microfluidics ; Neutrophil Infiltration - drug effects ; Neutrophil Infiltration - immunology ; Neutrophils ; Neutrophils - drug effects ; Neutrophils - immunology ; Neutrophils - metabolism ; Risk factors ; Signal Transduction ; Wound healing ; Wound Healing - drug effects ; Wound Healing - immunology ; Wounds and injuries
Là 1 phần của: Nature reviews. Immunology, 2016-06, Vol.16 (6), p.378-391
Mô tả: Neutrophil migration and its role during inflammation has been the focus of increased interest in the past decade. Advances in live imaging and the use of new model systems have helped to uncover the behaviour of neutrophils in injured and infected tissues. Although neutrophils were considered to be short-lived effector cells that undergo apoptosis in damaged tissues, recent evidence suggests that neutrophil behaviour is more complex and, in some settings, neutrophils might leave sites of tissue injury and migrate back into the vasculature. The role of reverse migration and its contribution to resolution of inflammation remains unclear. In this Review, we discuss the different cues within tissues that mediate neutrophil forward and reverse migration in response to injury or infection and the implications of these mechanisms to human disease.
Nơi xuất bản: England: Nature Publishing Group
Ngôn ngữ: English
Số nhận dạng: ISSN: 1474-1733
EISSN: 1474-1741
DOI: 10.1038/nri.2016.49
PMID: 27231052
Nguồn: MEDLINE
ProQuest Central

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Neutrophil migration in infection and wound repair: going forward in reverse

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Jun 2016 ;Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. 2016. ;ISSN: 1474-1733 ;EISSN: 1474-1741 ;DOI: 10.1038/nri.2016.49 ;PMID: 27231052

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