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Chlamydia cell biology and pathogenesis

Nature reviews. Microbiology, 2016-06, Vol.14 (6), p.385-400 [Peer Reviewed Journal]

Copyright Nature Publishing Group Jun 2016 ;ISSN: 1740-1526 ;EISSN: 1740-1534 ;DOI: 10.1038/nrmicro.2016.30 ;PMID: 27108705

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Title:
Chlamydia cell biology and pathogenesis
Author: Elwell, Cherilyn ; Mirrashidi, Kathleen ; Engel, Joanne
Subjects: Bacterial Proteins - metabolism ; Chlamydia ; Chlamydia - genetics ; Chlamydia - immunology ; Chlamydia - pathogenicity ; Chlamydia - physiology ; Chlamydia Infections - immunology ; Chlamydia Infections - microbiology ; Chlamydia Infections - physiopathology ; Chlamydia trachomatis - pathogenicity ; Chlamydia trachomatis - physiology ; Cytoplasm - metabolism ; Cytoplasm - microbiology ; Host-Pathogen Interactions - genetics ; Humans ; Immunity, Innate ; Proteomics ; Type V Secretion Systems - metabolism
Is Part Of: Nature reviews. Microbiology, 2016-06, Vol.14 (6), p.385-400
Description: Chlamydia spp. are important causes of human disease for which no effective vaccine exists. These obligate intracellular pathogens replicate in a specialized membrane compartment and use a large arsenal of secreted effectors to survive in the hostile intracellular environment of the host. In this Review, we summarize the progress in decoding the interactions between Chlamydia spp. and their hosts that has been made possible by recent technological advances in chlamydial proteomics and genetics. The field is now poised to decipher the molecular mechanisms that underlie the intimate interactions between Chlamydia spp. and their hosts, which will open up many exciting avenues of research for these medically important pathogens.
Publisher: England: Nature Publishing Group
Language: English
Identifier: ISSN: 1740-1526
EISSN: 1740-1534
DOI: 10.1038/nrmicro.2016.30
PMID: 27108705
Source: MEDLINE
ProQuest Central

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Chlamydia cell biology and pathogenesis

Copyright Nature Publishing Group Jun 2016 ;ISSN: 1740-1526 ;EISSN: 1740-1534 ;DOI: 10.1038/nrmicro.2016.30 ;PMID: 27108705

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