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Genetics on the Fly: A Primer on the Drosophila Model System

Genetics (Austin), 2015-11, Vol.201 (3), p.815-842 [Peer Reviewed Journal]

Copyright © 2015 by the Genetics Society of America. ;Copyright Genetics Society of America Nov 2015 ;Copyright © 2015 by the Genetics Society of America 2015 ;ISSN: 1943-2631 ;ISSN: 0016-6731 ;EISSN: 1943-2631 ;DOI: 10.1534/genetics.115.183392 ;PMID: 26564900 ;CODEN: GENTAE

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  • Title:
    Genetics on the Fly: A Primer on the Drosophila Model System
  • Author: Hales, Karen G ; Korey, Christopher A ; Larracuente, Amanda M ; Roberts, David M
  • Subjects: Animals ; Comparative analysis ; Developmental biology ; Drosophila ; Drosophila - genetics ; Drosophila - physiology ; Genomics ; Insects ; Models, Biological ; Models, Genetic ; Primer
  • Is Part Of: Genetics (Austin), 2015-11, Vol.201 (3), p.815-842
  • Description: Fruit flies of the genus Drosophila have been an attractive and effective genetic model organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them a century ago. Work with Drosophila has enabled dramatic advances in cell and developmental biology, neurobiology and behavior, molecular biology, evolutionary and population genetics, and other fields. With more tissue types and observable behaviors than in other short-generation model organisms, and with vast genome data available for many species within the genus, the fly's tractable complexity will continue to enable exciting opportunities to explore mechanisms of complex developmental programs, behaviors, and broader evolutionary questions. This primer describes the organism's natural history, the features of sequenced genomes within the genus, the wide range of available genetic tools and online resources, the types of biological questions Drosophila can help address, and historical milestones.
  • Publisher: United States: Genetics Society of America
  • Language: English
  • Identifier: ISSN: 1943-2631
    ISSN: 0016-6731
    EISSN: 1943-2631
    DOI: 10.1534/genetics.115.183392
    PMID: 26564900
    CODEN: GENTAE
  • Source: MEDLINE
    Alma/SFX Local Collection
    ProQuest Central
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