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Electrical synapses and their functional interactions with chemical synapses

Nature reviews. Neuroscience, 2014-04, Vol.15 (4), p.250-263 [Peer Reviewed Journal]

COPYRIGHT 2014 Nature Publishing Group ;Copyright Nature Publishing Group Apr 2014 ;ISSN: 1471-003X ;EISSN: 1471-0048 ;DOI: 10.1038/nrn3708 ;PMID: 24619342

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  • Title:
    Electrical synapses and their functional interactions with chemical synapses
  • Author: Pereda, Alberto E
  • Subjects: Animals ; Brain ; Brain - physiology ; Electrical Synapses - physiology ; Humans ; Neural transmission ; Neurological research ; Neurons - physiology ; Physiological aspects ; Synapses ; Synaptic Transmission - physiology
  • Is Part Of: Nature reviews. Neuroscience, 2014-04, Vol.15 (4), p.250-263
  • Description: Brain function relies on the ability of neurons to communicate with each other. Interneuronal communication primarily takes place at synapses, where information from one neuron is rapidly conveyed to a second neuron. There are two main modalities of synaptic transmission: chemical and electrical. Far from functioning independently and serving unrelated functions, mounting evidence indicates that these two modalities of synaptic transmission closely interact, both during development and in the adult brain. Rather than conceiving synaptic transmission as either chemical or electrical, this article emphasizes the notion that synaptic transmission is both chemical and electrical, and that interactions between these two forms of interneuronal communication might be required for normal brain development and function.
  • Publisher: England: Nature Publishing Group
  • Language: English
  • Identifier: ISSN: 1471-003X
    EISSN: 1471-0048
    DOI: 10.1038/nrn3708
    PMID: 24619342
  • Source: ProQuest One Psychology
    MEDLINE
    ProQuest Central
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