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Convex fiber-tapered seven core fiber-convex fiber (CTC) structure-based biosensor for creatinine detection in aquaculture

Optics express, 2022-04, Vol.30 (8), p.13898-13914 [Peer Reviewed Journal]

ISSN: 1094-4087 ;EISSN: 1094-4087 ;DOI: 10.1364/OE.457958 ;PMID: 35472993

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  • Title:
    Convex fiber-tapered seven core fiber-convex fiber (CTC) structure-based biosensor for creatinine detection in aquaculture
  • Author: Li, Muyang ; Singh, Ragini ; Soares, Maria Simone ; Marques, Carlos ; Zhang, Bingyuan ; Kumar, Santosh
  • Subjects: Aquaculture ; Biosensing Techniques - methods ; Creatinine ; Gold - chemistry ; Metal Nanoparticles - chemistry ; Reproducibility of Results ; Surface Plasmon Resonance - methods
  • Is Part Of: Optics express, 2022-04, Vol.30 (8), p.13898-13914
  • Description: The purpose of this article is to propose an optical fiber sensor probe based on the localized surface plasma resonance (LSPR) technique for the detection of creatinine in aquaculture. The sensing probe is functionalized through the use of gold nanoparticles (AuNPs), niobium carbide (Nb CTx) MXene, and creatinase (CA) enzyme. The intrinsic total internal reflection (TIR) mechanism is modified to increase the evanescent field intensity using a heterogeneous core mismatch and tapering probe structure (i.e., convex fiber-tapered seven core fiber-convex fiber (CTC) structure). Strong evanescent fields can stimulate AuNPs and induce the LSPR effect, thereby increasing probe sensitivity. The specific recognition is enhanced by Nb CTx MXene adsorbing more active CA enzymes. The developed sensor probe has a sensitivity and limit of detection of 3.1 pm/µM and 86.12 µM, respectively, in the linear range of 0-2000 µM. Additionally, the sensor probe's reusability, reproducibility, stability, and selectivity were evaluated, with satisfactory results obtained with impact for areas like food protein, marine life and healthcare.
  • Publisher: United States
  • Language: English
  • Identifier: ISSN: 1094-4087
    EISSN: 1094-4087
    DOI: 10.1364/OE.457958
    PMID: 35472993
  • Source: Geneva Foundation Free Medical Journals at publisher websites
    MEDLINE
    Alma/SFX Local Collection
    ROAD: Directory of Open Access Scholarly Resources
    DOAJ Directory of Open Access Journals
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