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Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement

Redox biology, 2020-10, Vol.37, p.101674-101674, Article 101674 [Peer Reviewed Journal]

2020 The Author(s) ;Copyright © 2020 The Author(s). Published by Elsevier B.V. All rights reserved. ;2020 The Author(s) 2020 ;ISSN: 2213-2317 ;EISSN: 2213-2317 ;DOI: 10.1016/j.redox.2020.101674 ;PMID: 32811789

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  • Title:
    Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement
  • Author: Nolfi-Donegan, Deirdre ; Braganza, Andrea ; Shiva, Sruti
  • Subjects: Electron transport chain ; Mitochondria ; Mitochondrial reactive oxygen species ; Oxidative phosphorylation ; Review
  • Is Part Of: Redox biology, 2020-10, Vol.37, p.101674-101674, Article 101674
  • Description: The mitochondrial electron transport chain utilizes a series of electron transfer reactions to generate cellular ATP through oxidative phosphorylation. A consequence of electron transfer is the generation of reactive oxygen species (ROS), which contributes to both homeostatic signaling as well as oxidative stress during pathology. In this graphical review we provide an overview of oxidative phosphorylation and its inter-relationship with ROS production by the electron transport chain. We also outline traditional and novel translational methodology for assessing mitochondrial energetics in health and disease.
  • Publisher: Netherlands: Elsevier B.V
  • Language: English
  • Identifier: ISSN: 2213-2317
    EISSN: 2213-2317
    DOI: 10.1016/j.redox.2020.101674
    PMID: 32811789
  • Source: Directory of Open Access Journals
    NCBI PubMed Central（免费）
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