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An encounter with alobar holoprosencephaly: a case report

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2020-07, Vol.9 (7), p.3069

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Title:
An encounter with alobar holoprosencephaly: a case report
Author: Venugopalan, Prasanna ; Mithilag, Fathima ; Nair, Vidhu V
Subjects: Obstetrics
Is Part Of: International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2020-07, Vol.9 (7), p.3069
Description: Alobar holopresencephaly is a rare embryonic condition where there is anomalous fusion of cerebral hemispheres. The key features include neurological impairment and facial dysmorphism like cyclopia, ocular hypertelorism with divided orbits and a proboscis. Obstetric ultrasound and foetal MRI are the diagnostic modalities. Majority of cases are sporadic in origin while a genetic association is also described. A small recurrence risk is noted in cases with sporadic origin. Early diagnosis and pregnancy termination are advisable for the condition since the survival rate is very low.
Publisher: International Journal of Reproduction, Contraception, Obstetrics and Gynecology
Language: English
Identifier: ISSN: 2320-1770
EISSN: 2320-1789
DOI: 10.18203/2320-1770.ijrcog20202761
Source: ROAD: Directory of Open Access Scholarly Resources

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