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Integrated genomic and molecular characterization of cervical cancerNature (London), 2017-03, Vol.543 (7645), p.378-384 [Peer Reviewed Journal]COPYRIGHT 2017 Nature Publishing Group ;COPYRIGHT 2017 Nature Publishing Group ;Copyright Nature Publishing Group Mar 16, 2017 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature21386 ;PMID: 28112728 ;CODEN: NATUASFull text available |
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Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancersNature medicine, 2019-04, Vol.25 (4), p.620-627 [Peer Reviewed Journal]COPYRIGHT 2019 Nature Publishing Group ;COPYRIGHT 2019 Nature Publishing Group ;2019© The Author(s), under exclusive licence to Springer Nature America, Inc. 2019 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/s41591-019-0367-9 ;PMID: 30833748Full text available |
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KRAS-MEK Signaling Controls Ago2 Sorting into ExosomesCell reports (Cambridge), 2016-05, Vol.15 (5), p.978-987 [Peer Reviewed Journal]2016 The Authors ;Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved. ;ISSN: 2211-1247 ;EISSN: 2211-1247 ;DOI: 10.1016/j.celrep.2016.03.085 ;PMID: 27117408Full text available |
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Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RASNature (London), 2017-08, Vol.548 (7666), p.234-238 [Peer Reviewed Journal]COPYRIGHT 2017 Nature Publishing Group ;COPYRIGHT 2017 Nature Publishing Group ;Copyright Nature Publishing Group Aug 10, 2017 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature23291 ;PMID: 28783719Full text available |
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RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancersNature cell biology, 2018-09, Vol.20 (9), p.1064-1073 [Peer Reviewed Journal]COPYRIGHT 2018 Nature Publishing Group ;COPYRIGHT 2018 Nature Publishing Group ;Copyright Nature Publishing Group Sep 2018 ;ISSN: 1465-7392 ;EISSN: 1476-4679 ;DOI: 10.1038/s41556-018-0169-1 ;PMID: 30104724Full text available |
6 |
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Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via PyroptosisCancer discovery, 2020-02, Vol.10 (2), p.254-2692019 American Association for Cancer Research. ;ISSN: 2159-8274 ;EISSN: 2159-8290 ;DOI: 10.1158/2159-8290.cd-19-0672 ;PMID: 31796433Full text available |
7 |
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Compromised MAPK signaling in human diseases: an updateArchives of toxicology, 2015-06, Vol.89 (6), p.867-882 [Peer Reviewed Journal]Springer-Verlag Berlin Heidelberg 2015 ;ISSN: 0340-5761 ;EISSN: 1432-0738 ;DOI: 10.1007/s00204-015-1472-2 ;PMID: 25690731Full text available |
8 |
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ERECTA1 Acts Upstream of the OsMKKK10-OsMKK4-OsMPK6 Cascade to Control Spikelet Number by Regulating Cytokinin Metabolism in RiceThe Plant cell, 2020-09, Vol.32 (9), p.2763-2779 [Peer Reviewed Journal]2020 American Society of Plant Biologists. All rights reserved. 2020 ;2020 American Society of Plant Biologists. All rights reserved. ;ISSN: 1040-4651 ;EISSN: 1532-298X ;DOI: 10.1105/tpc.20.00351 ;PMID: 32616661Full text available |
9 |
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The toxicity of silica nanoparticles to the immune systemNanomedicine, 2018-08, Vol.13 (14), p.1939-1962 [Peer Reviewed Journal]2018 Longquan Shao & Liangjiao Chen ;2018. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1743-5889 ;EISSN: 1748-6963 ;DOI: 10.2217/nnm-2018-0076 ;PMID: 30152253Full text available |
10 |
Material Type: Article
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivityNature (London), 2012-03, Vol.483 (7391), p.603-607 [Peer Reviewed Journal]2015 INIST-CNRS ;COPYRIGHT 2012 Nature Publishing Group ;COPYRIGHT 2012 Nature Publishing Group ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature11003 ;PMID: 22460905 ;CODEN: NATUASFull text available |
11 |
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Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistanceNature (London), 2013-02, Vol.494 (7436), p.251-255 [Peer Reviewed Journal]COPYRIGHT 2013 Nature Publishing Group ;COPYRIGHT 2013 Nature Publishing Group ;Copyright Nature Publishing Group Feb 14, 2013 ;2013 Macmillan Publishers Limited. All rights reserved 2013 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature11814 ;PMID: 23302800 ;CODEN: NATUASFull text available |
12 |
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Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth SuppressionCancer cell, 2016-01, Vol.29 (1), p.75-89 [Peer Reviewed Journal]2016 Elsevier Inc. ;Copyright © 2016 Elsevier Inc. All rights reserved. ;ISSN: 1535-6108 ;EISSN: 1878-3686 ;DOI: 10.1016/j.ccell.2015.11.011 ;PMID: 26725216Full text available |
13 |
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MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancerNature communications, 2019-05, Vol.10 (1), p.2197-17, Article 2197 [Peer Reviewed Journal]The Author(s) 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-019-09898-0 ;PMID: 31097693Full text available |
14 |
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Structural basis for the action of the drug trametinib at KSR-bound MEKNature (London), 2020-12, Vol.588 (7838), p.509-514 [Peer Reviewed Journal]Copyright Nature Publishing Group Dec 17, 2020 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-020-2760-4 ;PMID: 32927473Full text available |
15 |
Material Type: Article
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E3 ligases and deubiquitinating enzymes regulating the MAPK signaling pathway in cancersBiochimica et biophysica acta. Reviews on cancer, 2022-05, Vol.1877 (3), p.188736 [Peer Reviewed Journal]Copyright © 2022 Elsevier B.V. All rights reserved. ;EISSN: 1879-2561 ;DOI: 10.1016/j.bbcan.2022.188736 ;PMID: 35589008Digital Resources/Online E-Resources |
16 |
Material Type: Article
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Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer TherapyCells (Basel, Switzerland), 2020-01, Vol.9 (1), p.198 [Peer Reviewed Journal]2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 by the authors. 2020 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells9010198 ;PMID: 31941155Full text available |
17 |
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Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitorsCell reports (Cambridge), 2021-11, Vol.37 (5), p.109955-109955, Article 109955 [Peer Reviewed Journal]2021 The Author(s) ;Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved. ;ISSN: 2211-1247 ;EISSN: 2211-1247 ;DOI: 10.1016/j.celrep.2021.109955 ;PMID: 34731634Full text available |
18 |
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Polystyrene nanoplastics decrease nutrient accumulation, disturb sex hormones, and inhibit reproductive development in juvenile Macrobrachium nipponenseThe Science of the total environment, 2023-09, Vol.891, p.164481 [Peer Reviewed Journal]Copyright © 2023 Elsevier B.V. All rights reserved. ;EISSN: 1879-1026 ;DOI: 10.1016/j.scitotenv.2023.164481 ;PMID: 37257611Digital Resources/Online E-Resources |
19 |
Material Type: Article
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The Activation of MAPK in Melanoma Cells Resistant to BRAF Inhibition Promotes PD-L1 Expression That Is Reversible by MEK and PI3K InhibitionClinical cancer research, 2013-02, Vol.19 (3), p.598-609 [Peer Reviewed Journal]2014 INIST-CNRS ;ISSN: 1078-0432 ;EISSN: 1557-3265 ;DOI: 10.1158/1078-0432.CCR-12-2731 ;PMID: 23095323 ;CODEN: CCREF4Full text available |
20 |
Material Type: Article
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Multilayered synergistic regulation of phytoalexin biosynthesis by ethylene, jasmonate, and MAPK signaling pathways in ArabidopsisThe Plant cell, 2022-07, Vol.34 (8), p.3066-3087 [Peer Reviewed Journal]American Society of Plant Biologists 2022. All rights reserved. For permissions, please email: journals.permissions@oup.com. ;American Society of Plant Biologists 2022. All rights reserved. For permissions, please email: journals.permissions@oup.com 2022 ;ISSN: 1040-4651 ;EISSN: 1532-298X ;DOI: 10.1093/plcell/koac139 ;PMID: 35543483Full text available |