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1 |
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Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s DiseaseNeuron (Cambridge, Mass.), 2019-08, Vol.103 (4), p.627-641.e7 [Peer Reviewed Journal]2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;2019. Elsevier Inc. ;ISSN: 0896-6273 ;EISSN: 1097-4199 ;DOI: 10.1016/j.neuron.2019.05.035 ;PMID: 31255487Full text available |
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Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primatesBrain (London, England : 1878), 2020-05, Vol.143 (5), p.1462-1475 [Peer Reviewed Journal]The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For permissions, please email: journals.permissions@oup.com. ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awaa096 ;PMID: 32380543Full text available |
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α-Synuclein strains cause distinct synucleinopathies after local and systemic administrationNature (London), 2015-06, Vol.522 (7556), p.340-344 [Peer Reviewed Journal]Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature14547 ;PMID: 26061766Full text available |
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Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in miceThe Journal of experimental medicine, 2012-05, Vol.209 (5), p.975-986 [Peer Reviewed Journal]2012 Luk et al. 2012 ;ISSN: 0022-1007 ;EISSN: 1540-9538 ;DOI: 10.1084/jem.20112457 ;PMID: 22508839Full text available |
5 |
Material Type: Article
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Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ PathologyNeuron (Cambridge, Mass.), 2020-01, Vol.105 (2), p.260-275.e6 [Peer Reviewed Journal]2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;2019. Elsevier Inc. ;ISSN: 0896-6273 ;EISSN: 1097-4199 ;DOI: 10.1016/j.neuron.2019.10.010 ;PMID: 31759806Full text available |
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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic miceProceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10732-10737 [Peer Reviewed Journal]copyright © 1993—2008 National Academy of Sciences of the United States of America ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1321785111 ;PMID: 25002524Full text available |
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Material Type: Article
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Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeysAnnals of neurology, 2014-03, Vol.75 (3), p.351-362 [Peer Reviewed Journal]2014 Child Neurology Society/American Neurological Association ;2014 Child Neurology Society/American Neurological Association. ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 0364-5134 ;EISSN: 1531-8249 ;DOI: 10.1002/ana.24066 ;PMID: 24243558Full text available |
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Material Type: Article
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Prion-like spreading of pathological α-synuclein in brainBrain (London, England : 1878), 2013-04, Vol.136 (Pt 4), p.1128-1138 [Peer Reviewed Journal]2014 INIST-CNRS ;The Author (2013). Published by Oxford University Press on behalf of the Guarantors of Brain. 2013 ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awt037 ;PMID: 23466394Full text available |
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Material Type: Article
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Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian PathologyMolecular therapy, 2019-12, Vol.27 (12), p.2111-2122 [Peer Reviewed Journal]2019 The American Society of Gene and Cell Therapy ;Copyright © 2019 The American Society of Gene and Cell Therapy. Published by Elsevier Inc. All rights reserved. ;2019. The American Society of Gene and Cell Therapy ;2019 The American Society of Gene and Cell Therapy. 2019 The American Society of Gene and Cell Therapy ;ISSN: 1525-0016 ;EISSN: 1525-0024 ;DOI: 10.1016/j.ymthe.2019.08.010 ;PMID: 31501034Full text available |
10 |
Material Type: Article
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Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alterationBrain (London, England : 1878), 2019-05, Vol.142 (5), p.1365-1385 [Peer Reviewed Journal]The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2019 ;The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awz065 ;PMID: 30927362Full text available |
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Material Type: Article
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Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changesBrain (London, England : 1878), 2019-11, Vol.142 (11), p.3565-3579 [Peer Reviewed Journal]The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For permissions, please email: journals.permissions@oup.com. ;The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For permissions, please email: journals.permissions@oup.com 2019 ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awz296 ;PMID: 31580415Full text available |
12 |
Material Type: Article
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Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degenerationJournal of neuroinflammation, 2018-05, Vol.15 (1), p.129-18, Article 129 [Peer Reviewed Journal]COPYRIGHT 2018 BioMed Central Ltd. ;The Author(s). 2018 ;ISSN: 1742-2094 ;EISSN: 1742-2094 ;DOI: 10.1186/s12974-018-1171-z ;PMID: 29716614Full text available |
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Material Type: Article
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Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long termActa neuropathologica, 2018-01, Vol.135 (1), p.65-83 [Peer Reviewed Journal]The Author(s) 2017 ;Acta Neuropathologica is a copyright of Springer, (2017). All Rights Reserved. ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 0001-6322 ;EISSN: 1432-0533 ;DOI: 10.1007/s00401-017-1792-9 ;PMID: 29209768Full text available |
14 |
Material Type: Article
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Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury markerThe Journal of neuroscience, 2014-09, Vol.34 (37), p.12368-12378 [Peer Reviewed Journal]Copyright © 2014 the authors 0270-6474/14/3412368-11$15.00/0. ;Copyright © 2014 the authors 0270-6474/14/3412368-11$15.00/0 2014 ;ISSN: 0270-6474 ;EISSN: 1529-2401 ;DOI: 10.1523/JNEUROSCI.2102-14.2014 ;PMID: 25209277Full text available |
15 |
Material Type: Article
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Initiation of Parkinson's disease from gut to brain by δ-secretaseCell research, 2020-01, Vol.30 (1), p.70-87 [Peer Reviewed Journal]2019© IBCB, SIBS, CAS 2019 ;IBCB, SIBS, CAS 2019 ;ISSN: 1001-0602 ;EISSN: 1748-7838 ;DOI: 10.1038/s41422-019-0241-9 ;PMID: 31649329Full text available |
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Material Type: Article
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Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein FibrilsJournal of virology, 2017-01, Vol.91 (2) [Peer Reviewed Journal]Copyright © 2017 American Society for Microbiology. ;Copyright © 2017 American Society for Microbiology. 2017 American Society for Microbiology ;ISSN: 0022-538X ;EISSN: 1098-5514 ;DOI: 10.1128/JVI.02095-16 ;PMID: 27852849Full text available |
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Material Type: Article
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Intrastriatal injection of preformed alpha-synuclein fibrils alters central and peripheral immune cell profiles in non-transgenic miceJournal of neuroinflammation, 2019-12, Vol.16 (1), p.250-250, Article 250 [Peer Reviewed Journal]COPYRIGHT 2019 BioMed Central Ltd. ;2019. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s). 2019 ;ISSN: 1742-2094 ;EISSN: 1742-2094 ;DOI: 10.1186/s12974-019-1636-8 ;PMID: 31796095Full text available |
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Material Type: Article
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Autonomic ganglionic injection of α-synuclein fibrils as a model of pure autonomic failure α-synucleinopathyNature communications, 2020-02, Vol.11 (1), p.934-934, Article 934 [Peer Reviewed Journal]This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2020 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-019-14189-9 ;PMID: 32071315Full text available |
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Material Type: Article
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Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusionsNeurobiology of disease, 2020-02, Vol.134, p.104708-104708, Article 104708 [Peer Reviewed Journal]2019 ;Copyright © 2019. Published by Elsevier Inc. ;ISSN: 0969-9961 ;EISSN: 1095-953X ;DOI: 10.1016/j.nbd.2019.104708 ;PMID: 31837424Full text available |
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Material Type: Article
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Characterization of novel conformation-selective α-synuclein antibodies as potential immunotherapeutic agents for Parkinson's diseaseNeurobiology of disease, 2020-03, Vol.136, p.104712-104712, Article 104712 [Peer Reviewed Journal]2019 ;Copyright © 2019. Published by Elsevier Inc. ;ISSN: 0969-9961 ;EISSN: 1095-953X ;DOI: 10.1016/j.nbd.2019.104712 ;PMID: 31837422Full text available |