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CHOLANE DERIVATIVES FOR USE IN THE TREATMENT AND/OR PREVENTION OF FXR AND TGR5/GPBAR1 MEDIATED DISEASES
CHOLANE DERIVATIVES FOR USE IN THE TREATMENT AND/OR PREVENTION OF FXR AND TGR5/GPBAR1 MEDIATED DISEASES
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CHOLANE DERIVATIVES FOR USE IN THE TREATMENT AND/OR PREVENTION OF FXR AND TGR5/GPBAR1 MEDIATED DISEASES

Digital Resources/Online E-Resources

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2
Stereochemical Studies on Sphinxolide: Advances in the J-Based NMR Determination of the Relative Configuration of Flexible Systems
Stereochemical Studies on Sphinxolide: Advances in the J-Based NMR Determination of the Relative Configuration of Flexible Systems
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Stereochemical Studies on Sphinxolide: Advances in the J-Based NMR Determination of the Relative Configuration of Flexible Systems

European journal of organic chemistry, 2001-01, Vol.2001 (1), p.39-44 [Peer Reviewed Journal]

2001 WILEY‐VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany ;ISSN: 1434-193X ;EISSN: 1099-0690 ;DOI: 10.1002/1099-0690(200101)2001:1<39::AID-EJOC39>3.0.CO;2-9

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3
Stereochemical Studies on Sphinxolide: Advances in theJ-Based NMR Determination of the Relative Configuration of Flexible Systems
Stereochemical Studies on Sphinxolide: Advances in theJ-Based NMR Determination of the Relative Configuration of Flexible Systems
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Stereochemical Studies on Sphinxolide: Advances in theJ-Based NMR Determination of the Relative Configuration of Flexible Systems

European journal of organic chemistry, 2001-01, Vol.2001 (1), p.39-44 [Peer Reviewed Journal]

ISSN: 1434-193X ;EISSN: 1099-0690 ;DOI: 10.1002/1099-0690(200101)2001:1<39::AID-EJOC39>3.0.CO;2-9

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4
Quantum Mechanical Calculation of Coupling Constants in the Configurational Analysis of Flexible Systems: Determination of the Configuration of Callipeltin A
Quantum Mechanical Calculation of Coupling Constants in the Configurational Analysis of Flexible Systems: Determination of the Configuration of Callipeltin A
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Quantum Mechanical Calculation of Coupling Constants in the Configurational Analysis of Flexible Systems: Determination of the Configuration of Callipeltin A

European Journal of Organic Chemistry, 2006-02, Vol.2006 (3), p.604-609 [Peer Reviewed Journal]

Copyright © 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim ;ISSN: 1434-193X ;EISSN: 1099-0690 ;DOI: 10.1002/ejoc.200500740

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5
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis
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The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

The Journal of immunology (1950), 2017-07, Vol.199 (2), p.718-733 [Peer Reviewed Journal]

Copyright © 2017 by The American Association of Immunologists, Inc. ;Copyright American Association of Immunologists Jul 15, 2017 ;ISSN: 0022-1767 ;EISSN: 1550-6606 ;DOI: 10.4049/jimmunol.1700183 ;PMID: 28607110

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6
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity
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The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity

The Journal of immunology (1950), 2020-05, Vol.204 (9), p.2535-2551 [Peer Reviewed Journal]

Copyright © 2020 by The American Association of Immunologists, Inc. ;ISSN: 0022-1767 ;EISSN: 1550-6606 ;DOI: 10.4049/jimmunol.1901427 ;PMID: 32213564

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7
GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis
GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis
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GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis

Cellular and molecular gastroenterology and hepatology, 2019-01, Vol.8 (3), p.447-473 [Peer Reviewed Journal]

The Authors ;2019 The Authors ;Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved. ;2019 The Authors 2019 ;ISSN: 2352-345X ;EISSN: 2352-345X ;DOI: 10.1016/j.jcmgh.2019.06.003 ;PMID: 31226434

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8
Discovery of a AhR flavonoid agonist that counter-regulates ACE2 expression in rodent models of inflammation and attenuates ACE2-SARS-CoV2 interaction in vitro
Discovery of a AhR flavonoid agonist that counter-regulates ACE2 expression in rodent models of inflammation and attenuates ACE2-SARS-CoV2 interaction in vitro
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Discovery of a AhR flavonoid agonist that counter-regulates ACE2 expression in rodent models of inflammation and attenuates ACE2-SARS-CoV2 interaction in vitro

bioRxiv, 2021-02

2021. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (“the License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;DOI: 10.1101/2021.02.24.432203

Digital Resources/Online E-Resources

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9
GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
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GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation

Cells (Basel, Switzerland), 2022-04, Vol.11 (7), p.1187 [Peer Reviewed Journal]

2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells11071187 ;PMID: 35406751

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10
Perthamide C inhibits eNOS and iNOS expression and has immunomodulating activity in vivo
Perthamide C inhibits eNOS and iNOS expression and has immunomodulating activity in vivo
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Article 		Add to My Research

Perthamide C inhibits eNOS and iNOS expression and has immunomodulating activity in vivo

PloS one, 2013-03, Vol.8 (3), p.e57801 [Peer Reviewed Journal]

COPYRIGHT 2013 Public Library of Science ;COPYRIGHT 2013 Public Library of Science ;2013 Bucci et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2013 Bucci et al 2013 Bucci et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0057801 ;PMID: 23554869

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11
Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo. e57801
Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo. e57801
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Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo. e57801

PloS one, 2013-03, Vol.8 (3) [Peer Reviewed Journal]

EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0057801

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12
Sphinxolides E-G and reidispongiolide C: four new cytotoxic macrolides from the new caledonian lithistida sponges N. superstes and R. coeruleaXXX
Sphinxolides E-G and reidispongiolide C: four new cytotoxic macrolides from the new caledonian lithistida sponges N. superstes and R. coeruleaXXX
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Sphinxolides E-G and reidispongiolide C: four new cytotoxic macrolides from the new caledonian lithistida sponges N. superstes and R. coeruleaXXX

Tetrahedron, 1999-12, Vol.55 (51), p.14665-14674 [Peer Reviewed Journal]

1999 ;ISSN: 0040-4020 ;EISSN: 1464-5416 ;DOI: 10.1016/S0040-4020(99)00912-6

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13
ChemInform Abstract: Sphinxolides E-G and Reidispongiolide C: Four New Cytotoxic Macrolides from the New Caledonian Lithistida Sponges N. superstes and R. coerulea
ChemInform Abstract: Sphinxolides E-G and Reidispongiolide C: Four New Cytotoxic Macrolides from the New Caledonian Lithistida Sponges N. superstes and R. coerulea
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ChemInform Abstract: Sphinxolides E-G and Reidispongiolide C: Four New Cytotoxic Macrolides from the New Caledonian Lithistida Sponges N. superstes and R. coerulea

ChemInform, 2000-03, Vol.31 (10), p.no-no

Copyright © 2000 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim ;ISSN: 0931-7597 ;EISSN: 1522-2667 ;DOI: 10.1002/chin.200010230

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14
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis
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BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis

Scientific reports, 2017-02, Vol.7 (1), p.42801-42801, Article 42801 [Peer Reviewed Journal]

Copyright Nature Publishing Group Feb 2017 ;Copyright © 2017, The Author(s) 2017 The Author(s) ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep42801 ;PMID: 28202906

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15
Gpbar1 agonism promotes a Pgc-1&#945;-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
Gpbar1 agonism promotes a Pgc-1&#945;-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
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Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice

Scientific reports, 2017-10, Vol.7 (1), p.13689-13, Article 13689 [Peer Reviewed Journal]

2017. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2017 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-017-13102-y ;PMID: 29057935

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16
The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines
The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines
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The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines

Oncotarget, 2016-09, Vol.7 (38), p.61021-61035

Copyright: © 2016 Carino et al. 2016 ;ISSN: 1949-2553 ;EISSN: 1949-2553 ;DOI: 10.18632/oncotarget.10477 ;PMID: 27409173

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17
Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential
Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential
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Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential

Frontiers in oncology, 2021-05, Vol.11, p.663771-663771 [Peer Reviewed Journal]

Copyright © 2021 Carino, Graziosi, Marchianò, Biagioli, Marino, Sepe, Zampella, Distrutti, Donini and Fiorucci. ;Copyright © 2021 Carino, Graziosi, Marchianò, Biagioli, Marino, Sepe, Zampella, Distrutti, Donini and Fiorucci 2021 Carino, Graziosi, Marchianò, Biagioli, Marino, Sepe, Zampella, Distrutti, Donini and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2021.663771 ;PMID: 34012923

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18
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis
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Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis

The FASEB journal, 2019-02, Vol.33 (2), p.2809-2822 [Peer Reviewed Journal]

FASEB ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.201801373RR ;PMID: 30303744

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19
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
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Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

Nutrients, 2019-05, Vol.11 (5), p.1132 [Peer Reviewed Journal]

2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu11051132 ;PMID: 31117231

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20
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy
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The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy

The FASEB journal, 2021-01, Vol.35 (1), p.e21271-n/a [Peer Reviewed Journal]

2020 Federation of American Societies for Experimental Biology ;2020 Federation of American Societies for Experimental Biology. ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.202001386R ;PMID: 33368684

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