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Black mamba venom peptides target acid-sensing ion channels to abolish painNature (London), 2012-10, Vol.490 (7421), p.552-555 [Peer Reviewed Journal]2015 INIST-CNRS ;COPYRIGHT 2012 Nature Publishing Group ;COPYRIGHT 2012 Nature Publishing Group ;Copyright Nature Publishing Group Oct 25, 2012 ;Attribution ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature11494 ;PMID: 23034652 ;CODEN: NATUASFull text available |
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The mechanism of resistance to favipiravir in influenzaProceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (45), p.11613-11618 [Peer Reviewed Journal]Volumes 1–89 and 106–115, copyright as a collective work only; author(s) retains copyright to individual articles ;Copyright © 2018 the Author(s). Published by PNAS. ;Copyright National Academy of Sciences Nov 6, 2018 ;Copyright © 2018 the Author(s). Published by PNAS. 2018 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1811345115 ;PMID: 30352857Full text available |
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Multiple mechanisms for CRISPR-Cas inhibition by anti-CRISPR proteinsNature (London), 2015-10, Vol.526 (7571), p.136-139 [Peer Reviewed Journal]COPYRIGHT 2015 Nature Publishing Group ;COPYRIGHT 2015 Nature Publishing Group ;Copyright Nature Publishing Group Oct 1, 2015 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature15254 ;PMID: 26416740 ;CODEN: NATUASFull text available |
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Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alterationBrain (London, England : 1878), 2019-05, Vol.142 (5), p.1365-1385 [Peer Reviewed Journal]The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2019 ;The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awz065 ;PMID: 30927362Full text available |
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Material Type: Article
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Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15BCell, 2018-08, Vol.174 (5), p.1216-1228.e19 [Peer Reviewed Journal]2018 MRC Laboratory of Molecular Biology ;Copyright © 2018 MRC Laboratory of Molecular Biology. Published by Elsevier Inc. All rights reserved. ;2018 MRC Laboratory of Molecular Biology 2018 ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2018.06.030 ;PMID: 30057111Full text available |
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Clinical improvement in psoriasis with specific targeting of interleukin-23Nature (London), 2015-05, Vol.521 (7551), p.222-226 [Peer Reviewed Journal]COPYRIGHT 2015 Nature Publishing Group ;COPYRIGHT 2015 Nature Publishing Group ;Copyright Nature Publishing Group May 14, 2015 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature14175 ;PMID: 25754330 ;CODEN: NATUASFull text available |
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Structure- and function-based design of Plasmodium-selective proteasome inhibitorsNature (London), 2016-02, Vol.530 (7589), p.233-236 [Peer Reviewed Journal]COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Feb 11, 2016 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature16936 ;PMID: 26863983 ;CODEN: NATUASFull text available |
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Structural Basis of Functional Transitions in Mammalian NMDA ReceptorsCell, 2020-07, Vol.182 (2), p.357-371.e13 [Peer Reviewed Journal]2020 Elsevier Inc. ;Copyright © 2020 Elsevier Inc. All rights reserved. ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2020.05.052 ;PMID: 32610085Full text available |
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Material Type: Article
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A Bacterial Virulence Protein Promotes Pathogenicity by Inhibiting the Bacterium’s Own F1Fo ATP SynthaseCell, 2013-07, Vol.154 (1), p.146-156 [Peer Reviewed Journal]2013 Elsevier Inc. ;Copyright © 2013 Elsevier Inc. All rights reserved. ;2013 Elsevier Inc. All rights reserved 2013 ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2013.06.004 ;PMID: 23827679Full text available |
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10 |
Material Type: Article
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Co‐inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunityEMBO reports, 2018-12, Vol.19 (12), p.n/a [Peer Reviewed Journal]2018 The Authors ;2018 The Authors. ;2018 EMBO ;ISSN: 1469-221X ;EISSN: 1469-3178 ;DOI: 10.15252/embr.201846512 ;PMID: 30279279Full text available |
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Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress responseeLife, 2015-04, Vol.4, p.e07314-e07314 [Peer Reviewed Journal]2015, Sidrauski et al. This work is licensed under the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/3.0/ ) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2015, Sidrauski et al 2015 Sidrauski et al ;ISSN: 2050-084X ;EISSN: 2050-084X ;DOI: 10.7554/elife.07314 ;PMID: 25875391Full text available |
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Inhibitors of BRAF dimers using an allosteric siteNature communications, 2020-09, Vol.11 (1), p.4370-4370, Article 4370 [Peer Reviewed Journal]The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2020 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-020-18123-2 ;PMID: 32873792Full text available |
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Material Type: Article
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STAT3 associates with vacuolar H + -ATPase and regulates cytosolic and lysosomal pHCell research, 2018-10, Vol.28 (10), p.996-1012 [Peer Reviewed Journal]2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;IBCB, SIBS, CAS 2018 ;ISSN: 1001-0602 ;EISSN: 1748-7838 ;DOI: 10.1038/s41422-018-0080-0 ;PMID: 30127373Full text available |
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Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging studyLancet neurology, 2008-09, Vol.7 (9), p.796-804 [Peer Reviewed Journal]Elsevier Ltd ;2008 Elsevier Ltd ;Copyright Elsevier Limited Sep 2008 ;ISSN: 1474-4422 ;EISSN: 1474-4465 ;DOI: 10.1016/S1474-4422(08)70173-X ;PMID: 18703004 ;CODEN: LANCAOFull text available |
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NMDA Receptor Subunits Have Differential Roles in Mediating Excitotoxic Neuronal Death Both In Vitro and In VivoThe Journal of neuroscience, 2007-03, Vol.27 (11), p.2846-2857 [Peer Reviewed Journal]Copyright © 2007 Society for Neuroscience 0270-6474/07/272846-12$15.00/0 2007 ;ISSN: 0270-6474 ;EISSN: 1529-2401 ;DOI: 10.1523/JNEUROSCI.0116-07.2007 ;PMID: 17360906Full text available |
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Crystal Structure of the Human Ecto-5′-Nucleotidase (CD73): Insights into the Regulation of Purinergic SignalingStructure (London), 2012-12, Vol.20 (12), p.2161-2173 [Peer Reviewed Journal]2012 Elsevier Ltd ;Copyright © 2012 Elsevier Ltd. All rights reserved. ;ISSN: 0969-2126 ;EISSN: 1878-4186 ;DOI: 10.1016/j.str.2012.10.001 ;PMID: 23142347Full text available |
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Inhibitors for the Immuno- and Constitutive Proteasome: Current and Future Trends in Drug DevelopmentAngewandte Chemie (International ed.), 2012-08, Vol.51 (35), p.8708-8720 [Peer Reviewed Journal]Copyright © 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim ;Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. ;ISSN: 1433-7851 ;EISSN: 1521-3773 ;DOI: 10.1002/anie.201201616 ;PMID: 22711561 ;CODEN: ACIEAYFull text available |
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Acetylcholine receptor (AChR) α5 subunit variant associated with risk for nicotine dependence and lung cancer reduces (α4β2)₂α5 AChR functionMolecular pharmacology, 2011-01, Vol.79 (1), p.119-125 [Peer Reviewed Journal]Copyright © 2011 The American Society for Pharmacology and Experimental Therapeutics ;ISSN: 0026-895X ;EISSN: 1521-0111 ;DOI: 10.1124/mol.110.066357 ;PMID: 20881005Full text available |
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Material Type: Article
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Nicotinic Receptors in the Habenulo-Interpeduncular System Are Necessary for Nicotine Withdrawal in MiceThe Journal of neuroscience, 2009-03, Vol.29 (10), p.3014-3018 [Peer Reviewed Journal]Copyright © 2009 Society for Neuroscience 0270-6474/09/293014-05$15.00/0 2009 ;ISSN: 0270-6474 ;EISSN: 1529-2401 ;DOI: 10.1523/JNEUROSCI.4934-08.2009 ;PMID: 19279237Full text available |
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Material Type: Article
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GluN2D N-Methyl-d-Aspartate Receptor Subunit Contribution to the Stimulation of Brain Activity and Gamma Oscillations by Ketamine: Implications for SchizophreniaThe Journal of pharmacology and experimental therapeutics, 2016-03, Vol.356 (3), p.702-711 [Peer Reviewed Journal]Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics. ;Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics 2016 ;ISSN: 1521-0103 ;ISSN: 0022-3565 ;EISSN: 1521-0103 ;DOI: 10.1124/jpet.115.230391 ;PMID: 26675679Full text available |