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1
The catalytic mechanism of cyclic GMP‐AMP synthase (cGAS) and implications for innate immunity and inhibition
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The catalytic mechanism of cyclic GMP‐AMP synthase (cGAS) and implications for innate immunity and inhibition

Protein science, 2017-12, Vol.26 (12), p.2367-2380 [Peer Reviewed Journal]

2017 The Authors Protein Science published by Wiley Periodicals, Inc. on behalf of The Protein Society ;2017 The Authors Protein Science published by Wiley Periodicals, Inc. on behalf of The Protein Society. ;2017 The Protein Society ;ISSN: 0961-8368 ;EISSN: 1469-896X ;DOI: 10.1002/pro.3304 ;PMID: 28940468

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2
cGAS is essential for the antitumor effect of immune checkpoint blockade
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cGAS is essential for the antitumor effect of immune checkpoint blockade

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.1637-1642 [Peer Reviewed Journal]

Volumes 1–89 and 106–114, copyright as a collective work only; author(s) retains copyright to individual articles ;Copyright National Academy of Sciences Feb 14, 2017 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1621363114 ;PMID: 28137885

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3
Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response
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Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response

Immunity (Cambridge, Mass.), 2018-10, Vol.49 (4), p.754-763.e4 [Peer Reviewed Journal]

2018 Elsevier Inc. ;Copyright © 2018 Elsevier Inc. All rights reserved. ;Copyright Elsevier Limited Oct 16, 2018 ;ISSN: 1074-7613 ;EISSN: 1097-4180 ;DOI: 10.1016/j.immuni.2018.09.016 ;PMID: 30332631

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4
Direct activation of a phospholipase by cyclic GMP-AMP in El Tor Vibrio cholerae
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Direct activation of a phospholipase by cyclic GMP-AMP in El Tor Vibrio cholerae

Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (26), p.E6048-E6055 [Peer Reviewed Journal]

Volumes 1–89 and 106–114, copyright as a collective work only; author(s) retains copyright to individual articles ;Copyright © 2018 the Author(s). Published by PNAS. ;Copyright National Academy of Sciences Jun 26, 2018 ;Copyright © 2018 the Author(s). Published by PNAS. 2018 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1801233115 ;PMID: 29891656

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5
Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-β Induction
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Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-β Induction

Frontiers in microbiology, 2017-09, Vol.8, p.1854-1854 [Peer Reviewed Journal]

Copyright © 2017 Kim, Kim, Stinski, Ahn and Song. 2017 Kim, Kim, Stinski, Ahn and Song ;ISSN: 1664-302X ;EISSN: 1664-302X ;DOI: 10.3389/fmicb.2017.01854 ;PMID: 29018427

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6
Corrigendum: Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-β Induction
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Corrigendum: Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-β Induction

Frontiers in microbiology, 2018-02, Vol.9, p.350-350 [Peer Reviewed Journal]

Copyright © 2018 Kim, Kim, Stinski, Ahn and Song. 2018 Kim, Kim, Stinski, Ahn and Song ;ISSN: 1664-302X ;EISSN: 1664-302X ;DOI: 10.3389/fmicb.2018.00350 ;PMID: 29517049

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7
Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-β levels
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Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-β levels

Future medicinal chemistry, 2018-06, Vol.10 (11), p.1301-1317 [Peer Reviewed Journal]

2018 Herman Sintim ;ISSN: 1756-8919 ;EISSN: 1756-8927 ;DOI: 10.4155/fmc-2017-0322 ;PMID: 29558821

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8
Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site
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Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site

Cancer Immunology, Immunotherapy, 2017-06, Vol.66 (6), p.705-716 [Peer Reviewed Journal]

Springer-Verlag Berlin Heidelberg 2017 ;Cancer Immunology, Immunotherapy is a copyright of Springer, 2017. ;ISSN: 0340-7004 ;EISSN: 1432-0851 ;DOI: 10.1007/s00262-017-1975-1 ;PMID: 28243692

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9
Protein synthesis inhibition and GADD34 control IFN‐β heterogeneous expression in response to dsRNA
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Protein synthesis inhibition and GADD34 control IFN‐β heterogeneous expression in response to dsRNA

The EMBO journal, 2017-03, Vol.36 (6), p.761-782 [Peer Reviewed Journal]

2017 The Authors ;2017 The Authors. ;Attribution ;ISSN: 0261-4189 ;EISSN: 1460-2075 ;DOI: 10.15252/embj.201695000 ;PMID: 28100675

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10
Structural Studies of the 3',3'-cGAMP Riboswitch Induced by Cognate and Noncognate Ligands Using Molecular Dynamics Simulation
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Structural Studies of the 3',3'-cGAMP Riboswitch Induced by Cognate and Noncognate Ligands Using Molecular Dynamics Simulation

International journal of molecular sciences, 2018-11, Vol.19 (11), p.3527 [Peer Reviewed Journal]

2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2018 by the authors. 2018 ;ISSN: 1422-0067 ;ISSN: 1661-6596 ;EISSN: 1422-0067 ;DOI: 10.3390/ijms19113527 ;PMID: 30423927

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11
Investigation of phosphorylated adjuvants co-encapsulated with a model cancer peptide antigen for the treatment of colorectal cancer and liver metastasis
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Investigation of phosphorylated adjuvants co-encapsulated with a model cancer peptide antigen for the treatment of colorectal cancer and liver metastasis

Vaccine, 2017-05, Vol.35 (19), p.2550-2557 [Peer Reviewed Journal]

Elsevier Ltd ;2017 Elsevier Ltd ;Copyright © 2017 Elsevier Ltd. All rights reserved. ;Copyright Elsevier Limited May 2, 2017 ;ISSN: 0264-410X ;EISSN: 1873-2518 ;DOI: 10.1016/j.vaccine.2017.03.067 ;PMID: 28385609

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12
cGAS/STING Pathway in Cancer: Jekyll and Hyde Story of Cancer Immune Response
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cGAS/STING Pathway in Cancer: Jekyll and Hyde Story of Cancer Immune Response

International journal of molecular sciences, 2017-11, Vol.18 (11), p.2456 [Peer Reviewed Journal]

Copyright MDPI AG 2017 ;2017 by the author. 2017 ;ISSN: 1422-0067 ;ISSN: 1661-6596 ;EISSN: 1422-0067 ;DOI: 10.3390/ijms18112456 ;PMID: 29156566

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13
Effects of STING stimulation on macrophages: STING agonists polarize into "classically" or "alternatively" activated macrophages?
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Effects of STING stimulation on macrophages: STING agonists polarize into "classically" or "alternatively" activated macrophages?

Human vaccines & immunotherapeutics, 2018-02, Vol.14 (2), p.285-287 [Peer Reviewed Journal]

2018 The Author(s). Published with license by Taylor & Francis © Takayuki Ohkuri, Akemi Kosaka, Toshihiro Nagato, and Hiroya Kobayashi 2018 ;2018 The Author(s). Published with license by Taylor & Francis 2018 The Author(s) ;ISSN: 2164-5515 ;EISSN: 2164-554X ;DOI: 10.1080/21645515.2017.1395995 ;PMID: 29064738

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14
cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue
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cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue

Medical sciences (Basel), 2017-12, Vol.5 (4), p.35 [Peer Reviewed Journal]

Copyright MDPI AG 2017 ;2017 by the authors. 2017 ;ISSN: 2076-3271 ;EISSN: 2076-3271 ;DOI: 10.3390/medsci5040035 ;PMID: 29258267

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15
Nucleotide Second Messenger Signaling as a Target for the Control of Bacterial Biofilm Formation
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Nucleotide Second Messenger Signaling as a Target for the Control of Bacterial Biofilm Formation

Current topics in medicinal chemistry, 2017-01, Vol.17 (17), p.1928-1944 [Peer Reviewed Journal]

Copyright Bentham Science Jul 2017 ;ISSN: 1568-0266 ;EISSN: 1873-4294 ;DOI: 10.2174/1568026617666170105144424

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16
Intranasal immunization of pigs with porcine reproductive and respiratory syndrome virus-like particles plus 2', 3'-cGAMP VacciGrade™ adjuvant exacerbates viremia after virus challenge
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Intranasal immunization of pigs with porcine reproductive and respiratory syndrome virus-like particles plus 2', 3'-cGAMP VacciGrade™ adjuvant exacerbates viremia after virus challenge

Virology journal, 2017-04, Vol.14 (1), p.76-76, Article 76 [Peer Reviewed Journal]

COPYRIGHT 2017 BioMed Central Ltd. ;Copyright BioMed Central 2017 ;The Author(s). 2017 ;ISSN: 1743-422X ;EISSN: 1743-422X ;DOI: 10.1186/s12985-017-0746-0 ;PMID: 28403874

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17
cGAS/STING Pathway in Cancer
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cGAS/STING Pathway in Cancer

DOI: 10.17169/refubium-24180 ;DOI: 10.3390/ijms18112456

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