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1
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency
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Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Nature (London), 2020-12, Vol.588 (7838), p.459-465 [Peer Reviewed Journal]

COPYRIGHT 2020 Nature Publishing Group ;Copyright Nature Publishing Group Dec 17, 2020 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-020-2709-7 ;PMID: 32866962

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2
RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy
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RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy

Brain (London, England : 1878), 2019-12, Vol.142 (12), p.3753-3770 [Peer Reviewed Journal]

The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. ;The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. 2019 ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awz313 ;PMID: 31605140

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3
Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease
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Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease

Brain (London, England : 1878), 2017-12, Vol.140 (12), p.3081-3104 [Peer Reviewed Journal]

The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/awx198 ;PMID: 29053785

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4
Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy
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Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Molecular neurodegeneration, 2019-02, Vol.14 (1), p.9-15, Article 9 [Peer Reviewed Journal]

COPYRIGHT 2019 BioMed Central Ltd. ;Copyright © 2019. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s). 2019 ;ISSN: 1750-1326 ;EISSN: 1750-1326 ;DOI: 10.1186/s13024-019-0310-z ;PMID: 30767771

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5
Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy
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Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy

RNA biology, 2021-11, Vol.18 (11), p.1546-1554 [Peer Reviewed Journal]

2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2020 ;2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2020 The Author(s) ;ISSN: 1547-6286 ;EISSN: 1555-8584 ;DOI: 10.1080/15476286.2020.1860580 ;PMID: 33427561

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6
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response
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TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

PLoS genetics, 2019-05, Vol.15 (5), p.e1007947-e1007947 [Peer Reviewed Journal]

COPYRIGHT 2019 Public Library of Science ;COPYRIGHT 2019 Public Library of Science ;2019 Wang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 Wang et al 2019 Wang et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1007947 ;PMID: 31100073

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7
Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD
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Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD

Neurotherapeutics, 2022-07, Vol.19 (4), p.1061-1084 [Peer Reviewed Journal]

The American Society for Experimental NeuroTherapeutics, Inc. 2022 ;2022. The American Society for Experimental NeuroTherapeutics, Inc. ;The American Society for Experimental NeuroTherapeutics, Inc. 2022. ;ISSN: 1933-7213 ;ISSN: 1878-7479 ;EISSN: 1878-7479 ;DOI: 10.1007/s13311-022-01260-5 ;PMID: 35790708

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8
Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study
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Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study

Lancet neurology, 2018-09, Vol.17 (9), p.773-781 [Peer Reviewed Journal]

2018 Elsevier Ltd ;Copyright © 2018 Elsevier Ltd. All rights reserved. ;Copyright Elsevier Limited Sep 2018 ;ISSN: 1474-4422 ;EISSN: 1474-4465 ;DOI: 10.1016/S1474-4422(18)30251-5 ;PMID: 30093249

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9
CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration
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CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration

Annals of neurology, 2013-07, Vol.74 (1), p.39-52 [Peer Reviewed Journal]

Copyright © 2013 American Neurological Association ;Copyright © 2013 American Neurological Association. ;ISSN: 0364-5134 ;EISSN: 1531-8249 ;DOI: 10.1002/ana.23870 ;PMID: 23424178

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10
Abstract 1635 The role of Spermidine/spermine N1-acetyltransferase 1 and the polyamine stress response in TDP-43 proteinopathies
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Abstract 1635 The role of Spermidine/spermine N1-acetyltransferase 1 and the polyamine stress response in TDP-43 proteinopathies

The Journal of biological chemistry, 2024-03, Vol.300 (3) [Peer Reviewed Journal]

2024 The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1016/j.jbc.2024.106942

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11
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology
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Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

eLife, 2021-06, Vol.10 [Peer Reviewed Journal]

2021, Anderson et al. ;2021, Anderson et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021, Anderson et al 2021 Anderson et al ;ISSN: 2050-084X ;EISSN: 2050-084X ;DOI: 10.7554/eLife.67587 ;PMID: 34060470

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12
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43
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RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

Neuron (Cambridge, Mass.), 2019-04, Vol.102 (2), p.321-338.e8 [Peer Reviewed Journal]

2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;2019. Elsevier Inc. ;ISSN: 0896-6273 ;EISSN: 1097-4199 ;DOI: 10.1016/j.neuron.2019.01.048 ;PMID: 30826182

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13
Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death
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Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death

Neuron (Cambridge, Mass.), 2019-04, Vol.102 (2), p.339-357.e7 [Peer Reviewed Journal]

2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;2019. Elsevier Inc. ;ISSN: 0896-6273 ;EISSN: 1097-4199 ;DOI: 10.1016/j.neuron.2019.02.038 ;PMID: 30853299

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14
Targeting TDP-43 Pathology Alleviates Cognitive and Motor Deficits Caused by Chronic Cerebral Hypoperfusion
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Targeting TDP-43 Pathology Alleviates Cognitive and Motor Deficits Caused by Chronic Cerebral Hypoperfusion

Neurotherapeutics, 2021-04, Vol.18 (2), p.1095-1112 [Peer Reviewed Journal]

The American Society for Experimental NeuroTherapeutics, Inc. 2021 ;2021. The American Society for Experimental NeuroTherapeutics, Inc. ;The American Society for Experimental NeuroTherapeutics, Inc. 2021. ;ISSN: 1933-7213 ;ISSN: 1878-7479 ;EISSN: 1878-7479 ;DOI: 10.1007/s13311-021-01015-8 ;PMID: 33786804

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15
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy
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Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy

Nature neuroscience, 2018-03, Vol.21 (3), p.329-340 [Peer Reviewed Journal]

COPYRIGHT 2018 Nature Publishing Group ;COPYRIGHT 2018 Nature Publishing Group ;Copyright Nature Publishing Group Mar 2018 ;ISSN: 1097-6256 ;EISSN: 1546-1726 ;DOI: 10.1038/s41593-018-0083-7 ;PMID: 29463850

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16
Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis
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Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis

Neurobiology of disease, 2021-07, Vol.154, p.105360-105360, Article 105360 [Peer Reviewed Journal]

2021 The Authors ;Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved. ;ISSN: 0969-9961 ;EISSN: 1095-953X ;DOI: 10.1016/j.nbd.2021.105360 ;PMID: 33812000

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17
TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy
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TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy

Acta neuropathologica, 2021-10, Vol.142 (4), p.629-642 [Peer Reviewed Journal]

The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021 ;2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. ;COPYRIGHT 2021 Springer ;The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021. ;ISSN: 0001-6322 ;EISSN: 1432-0533 ;DOI: 10.1007/s00401-021-02330-2 ;PMID: 34152475

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18
Cryptic exon incorporation occurs in Alzheimer’s brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43
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Cryptic exon incorporation occurs in Alzheimer’s brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43

Acta neuropathologica, 2017-06, Vol.133 (6), p.923-931 [Peer Reviewed Journal]

Springer-Verlag Berlin Heidelberg 2017 ;COPYRIGHT 2017 Springer ;Acta Neuropathologica is a copyright of Springer, 2017. ;ISSN: 0001-6322 ;EISSN: 1432-0533 ;DOI: 10.1007/s00401-017-1701-2 ;PMID: 28332094

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19
Tau tubulin kinases in proteinopathy
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Tau tubulin kinases in proteinopathy

The FEBS journal, 2019-07, Vol.286 (13), p.2434-2446 [Peer Reviewed Journal]

Published 2019. This article is a U.S. Government work and is in the public domain in the USA. ;Copyright © 2019 Federation of European Biochemical Societies ;ISSN: 1742-464X ;EISSN: 1742-4658 ;DOI: 10.1111/febs.14866 ;PMID: 31034749

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20
Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans
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Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans

Acta neuropathologica, 2011-12, Vol.122 (6), p.715-726 [Peer Reviewed Journal]

Springer-Verlag 2011 ;Springer-Verlag 2011 2011 ;ISSN: 0001-6322 ;EISSN: 1432-0533 ;DOI: 10.1007/s00401-011-0909-9 ;PMID: 22101322

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