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1
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency
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Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Nature (London), 2020-12, Vol.588 (7838), p.459-465 [Peer Reviewed Journal]

COPYRIGHT 2020 Nature Publishing Group ;Copyright Nature Publishing Group Dec 17, 2020 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-020-2709-7 ;PMID: 32866962

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2
Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion
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Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion

The Journal of biological chemistry, 2013-07, Vol.288 (27), p.19614-19624 [Peer Reviewed Journal]

2013 © 2013 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2013 by The American Society for Biochemistry and Molecular Biology, Inc. 2013 ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M113.463828 ;PMID: 23689371

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3
TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy
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TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy

Journal of neuropathology and experimental neurology, 2010-09, Vol.69 (9), p.918-929 [Peer Reviewed Journal]

2010 American Association of Neuropathologists, Inc ;ISSN: 0022-3069 ;EISSN: 1554-6578 ;DOI: 10.1097/NEN.0b013e3181ee7d85 ;PMID: 20720505 ;CODEN: JNENAD

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4
Exosome secretion is a key pathway for clearance of pathological TDP-43
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Exosome secretion is a key pathway for clearance of pathological TDP-43

Brain (London, England : 1878), 2016-12, Vol.139 (Pt 12), p.3187-3201 [Peer Reviewed Journal]

The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ;The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2016 ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/aww237 ;PMID: 27679482

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5
Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy
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Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Molecular neurodegeneration, 2019-02, Vol.14 (1), p.9-15, Article 9 [Peer Reviewed Journal]

COPYRIGHT 2019 BioMed Central Ltd. ;Copyright © 2019. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s). 2019 ;ISSN: 1750-1326 ;EISSN: 1750-1326 ;DOI: 10.1186/s13024-019-0310-z ;PMID: 30767771

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6
Cortical influences drive amyotrophic lateral sclerosis
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Cortical influences drive amyotrophic lateral sclerosis

Journal of neurology, neurosurgery and psychiatry, 2017-11, Vol.88 (11), p.917-924 [Peer Reviewed Journal]

Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. ;Copyright: 2017 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. ;ISSN: 0022-3050 ;EISSN: 1468-330X ;DOI: 10.1136/jnnp-2017-315573 ;PMID: 28710326

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7
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response
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TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

PLoS genetics, 2019-05, Vol.15 (5), p.e1007947-e1007947 [Peer Reviewed Journal]

COPYRIGHT 2019 Public Library of Science ;COPYRIGHT 2019 Public Library of Science ;2019 Wang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 Wang et al 2019 Wang et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1007947 ;PMID: 31100073

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8
Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD
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Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD

Neurotherapeutics, 2022-07, Vol.19 (4), p.1061-1084 [Peer Reviewed Journal]

The American Society for Experimental NeuroTherapeutics, Inc. 2022 ;2022. The American Society for Experimental NeuroTherapeutics, Inc. ;The American Society for Experimental NeuroTherapeutics, Inc. 2022. ;ISSN: 1933-7213 ;ISSN: 1878-7479 ;EISSN: 1878-7479 ;DOI: 10.1007/s13311-022-01260-5 ;PMID: 35790708

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9
CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration
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CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration

Annals of neurology, 2013-07, Vol.74 (1), p.39-52 [Peer Reviewed Journal]

Copyright © 2013 American Neurological Association ;Copyright © 2013 American Neurological Association. ;ISSN: 0364-5134 ;EISSN: 1531-8249 ;DOI: 10.1002/ana.23870 ;PMID: 23424178

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10
Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy
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Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy

The Journal of neuroscience, 2016-07, Vol.36 (29), p.7707-7717 [Peer Reviewed Journal]

Copyright © 2016 the authors 0270-6474/16/367707-11$15.00/0. ;Copyright © 2016 the authors 0270-6474/16/367707-11$15.00/0 2016 ;ISSN: 0270-6474 ;EISSN: 1529-2401 ;DOI: 10.1523/JNEUROSCI.1457-16.2016 ;PMID: 27445147

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11
Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43
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Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (37), p.15024-15029 [Peer Reviewed Journal]

copyright © 1993-2008 National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences Sep 11, 2012 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1206362109 ;PMID: 22932872

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12
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology
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Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

eLife, 2021-06, Vol.10 [Peer Reviewed Journal]

2021, Anderson et al. ;2021, Anderson et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021, Anderson et al 2021 Anderson et al ;ISSN: 2050-084X ;EISSN: 2050-084X ;DOI: 10.7554/eLife.67587 ;PMID: 34060470

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13
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43
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RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

Neuron (Cambridge, Mass.), 2019-04, Vol.102 (2), p.321-338.e8 [Peer Reviewed Journal]

2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;2019. Elsevier Inc. ;ISSN: 0896-6273 ;EISSN: 1097-4199 ;DOI: 10.1016/j.neuron.2019.01.048 ;PMID: 30826182

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14
Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death
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Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death

Neuron (Cambridge, Mass.), 2019-04, Vol.102 (2), p.339-357.e7 [Peer Reviewed Journal]

2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;2019. Elsevier Inc. ;ISSN: 0896-6273 ;EISSN: 1097-4199 ;DOI: 10.1016/j.neuron.2019.02.038 ;PMID: 30853299

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15
Effective Inhibition of TDP‐43 Aggregation by Native State Stabilization
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Effective Inhibition of TDP‐43 Aggregation by Native State Stabilization

Angewandte Chemie International Edition, 2024-01 [Peer Reviewed Journal]

Attribution - NonCommercial ;ISSN: 1433-7851 ;EISSN: 1521-3773 ;DOI: 10.1002/anie.202314587 ;PMID: 37949836

Digital Resources/Online E-Resources

16
Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy
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Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy

Acta neuropathologica, 2024-05, Vol.147 (1) [Peer Reviewed Journal]

The Author(s) 2024 ;ISSN: 0001-6322 ;EISSN: 1432-0533 ;DOI: 10.1007/s00401-024-02732-y

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17
Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins
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Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins

Nature communications, 2023-10, Vol.14 (1), p.6492-6492, Article 6492 [Peer Reviewed Journal]

2023. Springer Nature Limited. ;The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Springer Nature Limited 2023 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-023-42147-z ;PMID: 37838698

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18
Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders
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Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders

Human molecular genetics, 2013-10, Vol.22 (R1), p.R77-R87 [Peer Reviewed Journal]

The Author 2013. Published by Oxford University Press. 2013 ;ISSN: 0964-6906 ;EISSN: 1460-2083 ;DOI: 10.1093/hmg/ddt349 ;PMID: 23900071

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19
TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expression
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TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expression

Nature communications, 2024-05, Vol.15 (1), p.4163-4163 [Peer Reviewed Journal]

2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply. ;This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-024-48488-7 ;PMID: 38755145

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20
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy
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Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy

Nature neuroscience, 2018-03, Vol.21 (3), p.329-340 [Peer Reviewed Journal]

COPYRIGHT 2018 Nature Publishing Group ;COPYRIGHT 2018 Nature Publishing Group ;Copyright Nature Publishing Group Mar 2018 ;ISSN: 1097-6256 ;EISSN: 1546-1726 ;DOI: 10.1038/s41593-018-0083-7 ;PMID: 29463850

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