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1 |
Material Type: Article
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Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic InclusionThe Journal of biological chemistry, 2013-07, Vol.288 (27), p.19614-19624 [Peer Reviewed Journal]2013 © 2013 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2013 by The American Society for Biochemistry and Molecular Biology, Inc. 2013 ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M113.463828 ;PMID: 23689371Full text available |
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Material Type: Article
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Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathyMolecular neurodegeneration, 2019-02, Vol.14 (1), p.9-15, Article 9 [Peer Reviewed Journal]COPYRIGHT 2019 BioMed Central Ltd. ;Copyright © 2019. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s). 2019 ;ISSN: 1750-1326 ;EISSN: 1750-1326 ;DOI: 10.1186/s13024-019-0310-z ;PMID: 30767771Full text available |
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Material Type: Article
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Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathyRNA biology, 2021-11, Vol.18 (11), p.1546-1554 [Peer Reviewed Journal]2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2020 ;2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 2020 The Author(s) ;ISSN: 1547-6286 ;EISSN: 1555-8584 ;DOI: 10.1080/15476286.2020.1860580 ;PMID: 33427561Full text available |
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Material Type: Article
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TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43Neurobiology of disease, 2024-04, Vol.193, p.106437-106437, Article 106437 [Peer Reviewed Journal]2024 The Authors ;Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved. ;2024 The Authors 2024 ;ISSN: 0969-9961 ;EISSN: 1095-953X ;DOI: 10.1016/j.nbd.2024.106437 ;PMID: 38367882Full text available |
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Material Type: Article
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TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein responsePLoS genetics, 2019-05, Vol.15 (5), p.e1007947-e1007947 [Peer Reviewed Journal]COPYRIGHT 2019 Public Library of Science ;COPYRIGHT 2019 Public Library of Science ;2019 Wang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 Wang et al 2019 Wang et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1007947 ;PMID: 31100073Full text available |
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Material Type: Article
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TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic TargetsNeurotherapeutics, 2015-04, Vol.12 (2), p.352-363 [Peer Reviewed Journal]The Author(s) 2015 ;The American Society for Experimental NeuroTherapeutics, Inc. 2015 ;ISSN: 1933-7213 ;ISSN: 1878-7479 ;EISSN: 1878-7479 ;DOI: 10.1007/s13311-015-0338-x ;PMID: 25652699Full text available |
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Material Type: Article
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Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTDNeurotherapeutics, 2022-07, Vol.19 (4), p.1061-1084 [Peer Reviewed Journal]The American Society for Experimental NeuroTherapeutics, Inc. 2022 ;2022. The American Society for Experimental NeuroTherapeutics, Inc. ;The American Society for Experimental NeuroTherapeutics, Inc. 2022. ;ISSN: 1933-7213 ;ISSN: 1878-7479 ;EISSN: 1878-7479 ;DOI: 10.1007/s13311-022-01260-5 ;PMID: 35790708Full text available |
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8 |
Material Type: Article
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Abstract 1635 The role of Spermidine/spermine N1-acetyltransferase 1 and the polyamine stress response in TDP-43 proteinopathiesThe Journal of biological chemistry, 2024-03, Vol.300 (3) [Peer Reviewed Journal]2024 The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1016/j.jbc.2024.106942Full text available |
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9 |
Material Type: Article
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Abstract 2222 Aggregation of TDP-43 in cellular overexpression model of ALSThe Journal of biological chemistry, 2024-03, Vol.300 (3) [Peer Reviewed Journal]2024 The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1016/j.jbc.2024.107066Full text available |
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Material Type: Article
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Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathologyeLife, 2021-06, Vol.10 [Peer Reviewed Journal]2021, Anderson et al. ;2021, Anderson et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021, Anderson et al 2021 Anderson et al ;ISSN: 2050-084X ;EISSN: 2050-084X ;DOI: 10.7554/eLife.67587 ;PMID: 34060470Full text available |
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11 |
Material Type: Article
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High glycine content in TDP-43: a potential culprit in limbic-predominant age-related TDP-43 encephalopathyJournal of international medical research, 2020-06, Vol.48 (6), p.300060520929853-300060520929853 [Peer Reviewed Journal]The Author(s) 2020 ;The Author(s) 2020. This work is licensed under the Creative Commons Attribution – Non-Commercial License https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2020 2020 SAGE Publications ;ISSN: 0300-0605 ;EISSN: 1473-2300 ;DOI: 10.1177/0300060520929853 ;PMID: 32529876Full text available |
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Material Type: Article
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Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide FibrilsThe Journal of biological chemistry, 2016-04, Vol.291 (17), p.8896-8907 [Peer Reviewed Journal]2016 © 2016 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2016 by The American Society for Biochemistry and Molecular Biology, Inc. ;2016 by The American Society for Biochemistry and Molecular Biology, Inc. 2016 The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M115.713552 ;PMID: 26887947Full text available |
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Material Type: Article
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Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteinsNature communications, 2023-10, Vol.14 (1), p.6492-6492, Article 6492 [Peer Reviewed Journal]2023. Springer Nature Limited. ;The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Springer Nature Limited 2023 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-023-42147-z ;PMID: 37838698Full text available |
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Material Type: Article
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Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patientsNature communications, 2014-09, Vol.5 (1), p.4824, Article 4824 [Peer Reviewed Journal]Copyright Nature Publishing Group Sep 2014 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/ncomms5824 ;PMID: 25215604Full text available |
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15 |
Material Type: Article
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Different 8-Hydroxyquinolines Protect Models of TDP-43 Protein, α-Synuclein, and Polyglutamine Proteotoxicity through Distinct MechanismsThe Journal of biological chemistry, 2012-02, Vol.287 (6), p.4107-4120 [Peer Reviewed Journal]2012 © 2012 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2012 by The American Society for Biochemistry and Molecular Biology, Inc. 2012 ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M111.308668 ;PMID: 22147697Full text available |
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Material Type: Article
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TDP-43 proteinopathy in ALS is triggered by loss of ASRGL1 and associated with HML-2 expressionNature communications, 2024-05, Vol.15 (1), p.4163-4163 [Peer Reviewed Journal]2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply. ;This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-024-48488-7 ;PMID: 38755145Full text available |
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17 |
Material Type: Article
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Limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change and microvascular pathologies in community‐dwelling older personsBrain pathology (Zurich, Switzerland), 2021-05, Vol.31 (3), p.e12939-n/a [Peer Reviewed Journal]2021 The Authors. Brain Pathology published by John Wiley & Sons Ltd on behalf of International Society of Neuropathology. ;2021. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1015-6305 ;EISSN: 1750-3639 ;DOI: 10.1111/bpa.12939 ;PMID: 33624322Full text available |
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18 |
Material Type: Article
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Targeting TDP-43 Pathology Alleviates Cognitive and Motor Deficits Caused by Chronic Cerebral HypoperfusionNeurotherapeutics, 2021-04, Vol.18 (2), p.1095-1112 [Peer Reviewed Journal]The American Society for Experimental NeuroTherapeutics, Inc. 2021 ;2021. The American Society for Experimental NeuroTherapeutics, Inc. ;The American Society for Experimental NeuroTherapeutics, Inc. 2021. ;ISSN: 1933-7213 ;ISSN: 1878-7479 ;EISSN: 1878-7479 ;DOI: 10.1007/s13311-021-01015-8 ;PMID: 33786804Full text available |
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Material Type: Article
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The role of TDP-43 mislocalization in amyotrophic lateral sclerosisMolecular neurodegeneration, 2020-08, Vol.15 (1), p.45-45, Article 45 [Peer Reviewed Journal]COPYRIGHT 2020 BioMed Central Ltd. ;2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2020 ;ISSN: 1750-1326 ;EISSN: 1750-1326 ;DOI: 10.1186/s13024-020-00397-1 ;PMID: 32799899Full text available |
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Material Type: Article
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Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in ratsThe Journal of clinical investigation, 2012-01, Vol.122 (1), p.107-118 [Peer Reviewed Journal]COPYRIGHT 2012 American Society for Clinical Investigation ;COPYRIGHT 2012 American Society for Clinical Investigation ;Copyright American Society for Clinical Investigation Jan 2012 ;Copyright © 2012, American Society for Clinical Investigation 2012 ;ISSN: 0021-9738 ;EISSN: 1558-8238 ;DOI: 10.1172/jci59130 ;PMID: 22156203Full text available |