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21
TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets
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TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

Neurotherapeutics, 2015-04, Vol.12 (2), p.352-363 [Peer Reviewed Journal]

The Author(s) 2015 ;The American Society for Experimental NeuroTherapeutics, Inc. 2015 ;ISSN: 1933-7213 ;ISSN: 1878-7479 ;EISSN: 1878-7479 ;DOI: 10.1007/s13311-015-0338-x ;PMID: 25652699

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22
Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD
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Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD

Neurotherapeutics, 2022-07, Vol.19 (4), p.1061-1084 [Peer Reviewed Journal]

The American Society for Experimental NeuroTherapeutics, Inc. 2022 ;2022. The American Society for Experimental NeuroTherapeutics, Inc. ;The American Society for Experimental NeuroTherapeutics, Inc. 2022. ;ISSN: 1933-7213 ;ISSN: 1878-7479 ;EISSN: 1878-7479 ;DOI: 10.1007/s13311-022-01260-5 ;PMID: 35790708

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23
CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration
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CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration

Annals of neurology, 2013-07, Vol.74 (1), p.39-52 [Peer Reviewed Journal]

Copyright © 2013 American Neurological Association ;Copyright © 2013 American Neurological Association. ;ISSN: 0364-5134 ;EISSN: 1531-8249 ;DOI: 10.1002/ana.23870 ;PMID: 23424178

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24
Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy
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Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy

The Journal of neuroscience, 2016-07, Vol.36 (29), p.7707-7717 [Peer Reviewed Journal]

Copyright © 2016 the authors 0270-6474/16/367707-11$15.00/0. ;Copyright © 2016 the authors 0270-6474/16/367707-11$15.00/0 2016 ;ISSN: 0270-6474 ;EISSN: 1529-2401 ;DOI: 10.1523/JNEUROSCI.1457-16.2016 ;PMID: 27445147

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25
Abstract 1635 The role of Spermidine/spermine N1-acetyltransferase 1 and the polyamine stress response in TDP-43 proteinopathies
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Abstract 1635 The role of Spermidine/spermine N1-acetyltransferase 1 and the polyamine stress response in TDP-43 proteinopathies

The Journal of biological chemistry, 2024-03, Vol.300 (3) [Peer Reviewed Journal]

2024 The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1016/j.jbc.2024.106942

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26
Abstract 2222 Aggregation of TDP-43 in cellular overexpression model of ALS
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Abstract 2222 Aggregation of TDP-43 in cellular overexpression model of ALS

The Journal of biological chemistry, 2024-03, Vol.300 (3) [Peer Reviewed Journal]

2024 The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1016/j.jbc.2024.107066

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27
Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43
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Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (37), p.15024-15029 [Peer Reviewed Journal]

copyright © 1993-2008 National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences Sep 11, 2012 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1206362109 ;PMID: 22932872

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28
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology
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Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

eLife, 2021-06, Vol.10 [Peer Reviewed Journal]

2021, Anderson et al. ;2021, Anderson et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021, Anderson et al 2021 Anderson et al ;ISSN: 2050-084X ;EISSN: 2050-084X ;DOI: 10.7554/eLife.67587 ;PMID: 34060470

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29
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43
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RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

Neuron (Cambridge, Mass.), 2019-04, Vol.102 (2), p.321-338.e8 [Peer Reviewed Journal]

2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;2019. Elsevier Inc. ;ISSN: 0896-6273 ;EISSN: 1097-4199 ;DOI: 10.1016/j.neuron.2019.01.048 ;PMID: 30826182

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30
Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death
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Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death

Neuron (Cambridge, Mass.), 2019-04, Vol.102 (2), p.339-357.e7 [Peer Reviewed Journal]

2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;2019. Elsevier Inc. ;ISSN: 0896-6273 ;EISSN: 1097-4199 ;DOI: 10.1016/j.neuron.2019.02.038 ;PMID: 30853299

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31
High glycine content in TDP-43: a potential culprit in limbic-predominant age-related TDP-43 encephalopathy
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High glycine content in TDP-43: a potential culprit in limbic-predominant age-related TDP-43 encephalopathy

Journal of international medical research, 2020-06, Vol.48 (6), p.300060520929853-300060520929853 [Peer Reviewed Journal]

The Author(s) 2020 ;The Author(s) 2020. This work is licensed under the Creative Commons Attribution – Non-Commercial License https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2020 2020 SAGE Publications ;ISSN: 0300-0605 ;EISSN: 1473-2300 ;DOI: 10.1177/0300060520929853 ;PMID: 32529876

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32
Effective Inhibition of TDP‐43 Aggregation by Native State Stabilization
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Effective Inhibition of TDP‐43 Aggregation by Native State Stabilization

Angewandte Chemie International Edition, 2024-01 [Peer Reviewed Journal]

Attribution - NonCommercial ;ISSN: 1433-7851 ;EISSN: 1521-3773 ;DOI: 10.1002/anie.202314587 ;PMID: 37949836

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33
Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species
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Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

Journal of cell science, 2014-03, Vol.127 (Pt 6), p.1263-1278 [Peer Reviewed Journal]

2014. Published by The Company of Biologists Ltd 2014 ;ISSN: 0021-9533 ;EISSN: 1477-9137 ;DOI: 10.1242/jcs.140087 ;PMID: 24424030

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34
Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils
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Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils

The Journal of biological chemistry, 2016-04, Vol.291 (17), p.8896-8907 [Peer Reviewed Journal]

2016 © 2016 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2016 by The American Society for Biochemistry and Molecular Biology, Inc. ;2016 by The American Society for Biochemistry and Molecular Biology, Inc. 2016 The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M115.713552 ;PMID: 26887947

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35
Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy
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Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy

Acta neuropathologica, 2024-05, Vol.147 (1) [Peer Reviewed Journal]

The Author(s) 2024 ;ISSN: 0001-6322 ;EISSN: 1432-0533 ;DOI: 10.1007/s00401-024-02732-y

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36
Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins
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Mitigating a TDP-43 proteinopathy by targeting ataxin-2 using RNA-targeting CRISPR effector proteins

Nature communications, 2023-10, Vol.14 (1), p.6492-6492, Article 6492 [Peer Reviewed Journal]

2023. Springer Nature Limited. ;The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Springer Nature Limited 2023 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-023-42147-z ;PMID: 37838698

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37
TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia
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TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia

Brain (London, England : 1878), 2016-11, Vol.139 (11), p.2983-2993 [Peer Reviewed Journal]

The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ;The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2016 ;ISSN: 0006-8950 ;EISSN: 1460-2156 ;DOI: 10.1093/brain/aww224 ;PMID: 27694152

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38
Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients
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Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

Nature communications, 2014-09, Vol.5 (1), p.4824, Article 4824 [Peer Reviewed Journal]

Copyright Nature Publishing Group Sep 2014 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/ncomms5824 ;PMID: 25215604

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39
Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders
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Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders

Human molecular genetics, 2013-10, Vol.22 (R1), p.R77-R87 [Peer Reviewed Journal]

The Author 2013. Published by Oxford University Press. 2013 ;ISSN: 0964-6906 ;EISSN: 1460-2083 ;DOI: 10.1093/hmg/ddt349 ;PMID: 23900071

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40
Different 8-Hydroxyquinolines Protect Models of TDP-43 Protein, α-Synuclein, and Polyglutamine Proteotoxicity through Distinct Mechanisms
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Different 8-Hydroxyquinolines Protect Models of TDP-43 Protein, α-Synuclein, and Polyglutamine Proteotoxicity through Distinct Mechanisms

The Journal of biological chemistry, 2012-02, Vol.287 (6), p.4107-4120 [Peer Reviewed Journal]

2012 © 2012 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2012 by The American Society for Biochemistry and Molecular Biology, Inc. 2012 ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M111.308668 ;PMID: 22147697

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