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Results 1 - 20 of 3,893  for All Library Resources

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1
The Role of PGC1α in Cancer Metabolism and its Therapeutic Implications
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The Role of PGC1α in Cancer Metabolism and its Therapeutic Implications

Molecular cancer therapeutics, 2016-05, Vol.15 (5), p.774-782 [Peer Reviewed Journal]

2016 American Association for Cancer Research. ;ISSN: 1535-7163 ;EISSN: 1538-8514 ;DOI: 10.1158/1535-7163.MCT-15-0621 ;PMID: 27197257

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2
Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma
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Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma

Journal of hepatology, 2021-06, Vol.74 (6), p.1373 [Peer Reviewed Journal]

Copyright © 2021 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved. ;EISSN: 1600-0641 ;DOI: 10.1016/j.jhep.2020.12.031 ;PMID: 33484774

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3
Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion
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Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Nature immunology, 2021-02, Vol.22 (2), p.205-215 [Peer Reviewed Journal]

COPYRIGHT 2021 Nature Publishing Group ;The Author(s), under exclusive licence to Springer Nature America, Inc. 2021. ;ISSN: 1529-2908 ;EISSN: 1529-2916 ;DOI: 10.1038/s41590-020-00834-9 ;PMID: 33398183

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4
PGC-1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI
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PGC-1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI

The Journal of pathology, 2019-09, Vol.249 (1), p.65 [Peer Reviewed Journal]

2019 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. ;EISSN: 1096-9896 ;DOI: 10.1002/path.5282 ;PMID: 30982966

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5
Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8+ T Cell Exhaustion
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Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8+ T Cell Exhaustion

Immunity (Cambridge, Mass.), 2016-08, Vol.45 (2), p.358-373 [Peer Reviewed Journal]

2016 Elsevier Inc. ;Copyright © 2016 Elsevier Inc. All rights reserved. ;Copyright Elsevier Limited Aug 16, 2016 ;ISSN: 1074-7613 ;EISSN: 1097-4180 ;DOI: 10.1016/j.immuni.2016.07.008 ;PMID: 27496729

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6
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction
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The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

Immunity (Cambridge, Mass.), 2016-08, Vol.45 (2), p.374-388 [Peer Reviewed Journal]

2016 Elsevier Inc. ;Copyright © 2016 Elsevier Inc. All rights reserved. ;Copyright Elsevier Limited Aug 16, 2016 ;ISSN: 1074-7613 ;EISSN: 1097-4180 ;DOI: 10.1016/j.immuni.2016.07.009 ;PMID: 27496732

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7
MiR-485-3p and miR-485-5p suppress breast cancer cell metastasis by inhibiting PGC-1α expression
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MiR-485-3p and miR-485-5p suppress breast cancer cell metastasis by inhibiting PGC-1α expression

Cell death & disease, 2016-03, Vol.7 (3), p.e2159-e2159 [Peer Reviewed Journal]

Copyright © 2016 Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2041-4889 ;EISSN: 2041-4889 ;DOI: 10.1038/cddis.2016.27 ;PMID: 27010860

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8
Melatonin prevents Drp1-mediated mitochondrial fission in diabetic hearts through SIRT1-PGC1α pathway
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Article
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Melatonin prevents Drp1-mediated mitochondrial fission in diabetic hearts through SIRT1-PGC1α pathway

Journal of pineal research, 2018-09, Vol.65 (2), p.e12491 [Peer Reviewed Journal]

2018 The Authors. Journal of Pineal Research Published by John Wiley & Sons Ltd. ;EISSN: 1600-079X ;DOI: 10.1111/jpi.12491 ;PMID: 29575122

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9
PGC‐1α, a potential therapeutic target against kidney aging
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PGC‐1α, a potential therapeutic target against kidney aging

Aging cell, 2019-10, Vol.18 (5), p.e12994-n/a [Peer Reviewed Journal]

2019 The Authors. published by the Anatomical Society and John Wiley & Sons Ltd. ;2019 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd. ;COPYRIGHT 2019 John Wiley & Sons, Inc. ;2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1474-9718 ;EISSN: 1474-9726 ;DOI: 10.1111/acel.12994 ;PMID: 31313501

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10
PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs
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PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs

Cell metabolism, 2017-11, Vol.26 (5), p.778-787.e5 [Peer Reviewed Journal]

2017 Elsevier Inc. ;Copyright © 2017 Elsevier Inc. All rights reserved. ;ISSN: 1550-4131 ;EISSN: 1932-7420 ;DOI: 10.1016/j.cmet.2017.09.006 ;PMID: 28988825

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11
NT-PGC-1α deficiency decreases mitochondrial FA oxidation in brown adipose tissue and alters substrate utilization in vivo
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Article
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NT-PGC-1α deficiency decreases mitochondrial FA oxidation in brown adipose tissue and alters substrate utilization in vivo

Journal of lipid research, 2018-09, Vol.59 (9), p.1660-1670 [Peer Reviewed Journal]

2018 © 2018 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;Copyright © 2018 Kim et al. ;Copyright © 2018 Kim et al. 2018 Kim et al. ;ISSN: 0022-2275 ;EISSN: 1539-7262 ;DOI: 10.1194/jlr.M085647 ;PMID: 30026188

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12
Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes
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Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes

The Journal of biological chemistry, 2016-07, Vol.291 (29), p.15169-15184 [Peer Reviewed Journal]

2016 © 2016 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2016 by The American Society for Biochemistry and Molecular Biology, Inc. ;2016 by The American Society for Biochemistry and Molecular Biology, Inc. 2016 The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;ISSN: 1083-351X ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M115.705822 ;PMID: 27231350

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13
Obesity causes PGC-1α deficiency in the pancreas leading to marked IL-6 upregulation via NF-κB in acute pancreatitis
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Article
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Obesity causes PGC-1α deficiency in the pancreas leading to marked IL-6 upregulation via NF-κB in acute pancreatitis

The Journal of pathology, 2019-01, Vol.247 (1), p.48 [Peer Reviewed Journal]

Copyright © 2018 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. ;EISSN: 1096-9896 ;DOI: 10.1002/path.5166 ;PMID: 30221360

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14
AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species
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Article
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AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

Cell reports (Cambridge), 2017-10, Vol.21 (1), p.1-9 [Peer Reviewed Journal]

2017 The Author(s) ;Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved. ;ISSN: 2211-1247 ;EISSN: 2211-1247 ;DOI: 10.1016/j.celrep.2017.09.026 ;PMID: 28978464

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15
Mitophagy receptor FUNDC1 is regulated by PGC‐1α/NRF1 to fine tune mitochondrial homeostasis
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Article
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Mitophagy receptor FUNDC1 is regulated by PGC‐1α/NRF1 to fine tune mitochondrial homeostasis

EMBO reports, 2021-03, Vol.22 (3), p.e50629-n/a [Peer Reviewed Journal]

2021 The Authors ;2021 The Authors. ;2021 EMBO ;ISSN: 1469-221X ;EISSN: 1469-3178 ;DOI: 10.15252/embr.202050629 ;PMID: 33554448

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16
Treatment with celastrol protects against obesity through suppression of galanin-induced fat intake and activation of PGC-1α/GLUT4 axis-mediated glucose consumption
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Article
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Treatment with celastrol protects against obesity through suppression of galanin-induced fat intake and activation of PGC-1α/GLUT4 axis-mediated glucose consumption

Biochimica et biophysica acta. Molecular basis of disease, 2019-06, Vol.1865 (6), p.1341 [Peer Reviewed Journal]

Copyright © 2019 Elsevier B.V. All rights reserved. ;EISSN: 1879-260X ;DOI: 10.1016/j.bbadis.2019.02.002 ;PMID: 30742994

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17
Metformin improves cardiac function in mice with heart failure after myocardial infarction by regulating mitochondrial energy metabolism
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Article
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Metformin improves cardiac function in mice with heart failure after myocardial infarction by regulating mitochondrial energy metabolism

Biochemical and biophysical research communications, 2017-04, Vol.486 (2), p.329 [Peer Reviewed Journal]

Copyright © 2017. Published by Elsevier Inc. ;EISSN: 1090-2104 ;DOI: 10.1016/j.bbrc.2017.03.036 ;PMID: 28302481

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18
KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial Biogenesis
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Article
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KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial Biogenesis

Molecular cell, 2019-12, Vol.76 (6), p.885-895.e7 [Peer Reviewed Journal]

2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;ISSN: 1097-2765 ;EISSN: 1097-4164 ;DOI: 10.1016/j.molcel.2019.09.019 ;PMID: 31629659

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19
Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis
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Article
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Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis

Mechanisms of ageing and development, 2016-04, Vol.155, p.10 [Peer Reviewed Journal]

Copyright © 2016 Elsevier Ireland Ltd. All rights reserved. ;EISSN: 1872-6216 ;DOI: 10.1016/j.mad.2016.02.003 ;PMID: 26923269

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20
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
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A PGC1α-mediated transcriptional axis suppresses melanoma metastasis

Nature (London), 2016-09, Vol.537 (7620), p.422-426 [Peer Reviewed Journal]

ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature19347 ;PMID: 27580028

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