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1 |
Material Type: Article
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Addressing dyslipidemic risk beyond LDL-cholesterolThe Journal of clinical investigation, 2022-01, Vol.132 (1), p.1-10 [Peer Reviewed Journal]COPYRIGHT 2022 American Society for Clinical Investigation ;Copyright American Society for Clinical Investigation Jan 2022 ;2022 Tall et al. 2022 Tall et al. ;ISSN: 1558-8238 ;ISSN: 0021-9738 ;EISSN: 1558-8238 ;DOI: 10.1172/JCI148559 ;PMID: 34981790Full text available |
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Material Type: Article
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In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levelsNature biotechnology, 2021-08, Vol.39 (8), p.949-957 [Peer Reviewed Journal]2021. The Author(s). ;COPYRIGHT 2021 Nature Publishing Group ;The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2021 ;ISSN: 1087-0156 ;EISSN: 1546-1696 ;DOI: 10.1038/s41587-021-00933-4 ;PMID: 34012094Full text available |
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Material Type: Article
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A robust and efficient method for Mendelian randomization with hundreds of genetic variantsNature communications, 2020-01, Vol.11 (1), p.376-376, Article 376 [Peer Reviewed Journal]This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2020 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-019-14156-4 ;PMID: 31953392Full text available |
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Material Type: Article
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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysisPLoS medicine, 2020-03, Vol.17 (3), p.e1003062-e1003062 [Peer Reviewed Journal]2020 Richardson et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 Richardson et al 2020 Richardson et al ;ISSN: 1549-1676 ;ISSN: 1549-1277 ;EISSN: 1549-1676 ;DOI: 10.1371/JOURNAL.PMED.1003062 ;PMID: 32203549Full text available |
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Material Type: Article
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Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trialThe Lancet (British edition), 2017-10, Vol.390 (10106), p.1962-1971 [Peer Reviewed Journal]2017 Elsevier Ltd ;Copyright © 2017 Elsevier Ltd. All rights reserved. ;Copyright Elsevier Limited Oct 28, 2017 ;ISSN: 0140-6736 ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(17)32290-0 ;PMID: 28859947Full text available |
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Material Type: Article
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2016 ACC Expert Consensus Decision Pathway on the Role of Non-Statin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Task Force on Clinical Expert Consensus DocumentsJournal of the American College of Cardiology, 2016-07, Vol.68 (1), p.92-125 [Peer Reviewed Journal]Copyright Elsevier Limited Jul 5, 2016 ;ISSN: 0735-1097 ;EISSN: 1558-3597 ;DOI: 10.1016/j.jacc.2016.03.519 ;PMID: 27046161Full text available |
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7 |
Material Type: Article
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Safety and Efficacy of Bempedoic Acid to Reduce LDL CholesterolThe New England journal of medicine, 2019-03, Vol.380 (11), p.1022-1032 [Peer Reviewed Journal]Copyright © 2019 Massachusetts Medical Society. All rights reserved. ;Copyright © 2019 Massachusetts Medical Society. ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa1803917 ;PMID: 30865796Full text available |
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8 |
Material Type: Article
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Triglyceride-Rich Lipoproteins and Atherosclerotic Cardiovascular Disease: New Insights From Epidemiology, Genetics, and BiologyCirculation research, 2016-02, Vol.118 (4), p.547-563 [Peer Reviewed Journal]2016 American Heart Association, Inc. ;ISSN: 0009-7330 ;EISSN: 1524-4571 ;DOI: 10.1161/CIRCRESAHA.115.306249 ;PMID: 26892957Full text available |
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9 |
Material Type: Article
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Discovery and refinement of loci associated with lipid levelsNature genetics, 2013-11, Vol.45 (11), p.1274-1283 [Peer Reviewed Journal]COPYRIGHT 2013 Nature Publishing Group ;COPYRIGHT 2013 Nature Publishing Group ;Copyright Nature Publishing Group Nov 2013 ;ISSN: 1061-4036 ;ISSN: 1546-1718 ;EISSN: 1546-1718 ;DOI: 10.1038/ng.2797 ;PMID: 24097068Full text available |
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10 |
Material Type: Article
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Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular EventsThe New England journal of medicine, 2015-04, Vol.372 (16), p.1489-1499 [Peer Reviewed Journal]Copyright © 2015 Massachusetts Medical Society. All rights reserved. ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa1501031 ;PMID: 25773378Full text available |
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11 |
Material Type: Article
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Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular EventsThe New England journal of medicine, 2015-04, Vol.372 (16), p.1500-1509 [Peer Reviewed Journal]Copyright © 2015 Massachusetts Medical Society. All rights reserved. ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa1500858 ;PMID: 25773607Full text available |
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12 |
Material Type: Article
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Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)The Lancet (British edition), 2021-11, Vol.398 (10312), p.1713-1725 [Peer Reviewed Journal]2021 Elsevier Ltd ;Copyright © 2021 Elsevier Ltd. All rights reserved. ;2021. Elsevier Ltd ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 0140-6736 ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(21)01122-3 ;PMID: 34506743Full text available |
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13 |
Material Type: Article
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PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trialThe Lancet (British edition), 2015-01, Vol.385 (9965), p.331-340 [Peer Reviewed Journal]Elsevier Ltd ;2015 Elsevier Ltd ;Copyright © 2015 Elsevier Ltd. All rights reserved. ;Copyright Elsevier Limited Jan 24, 2015 ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 0140-6736 ;ISSN: 1474-547X ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(14)61399-4 ;PMID: 25282519 ;CODEN: LANCAOFull text available |
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14 |
Material Type: Article
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Common variants associated with plasma triglycerides and risk for coronary artery diseaseNature genetics, 2013-11, Vol.45 (11), p.1345-1352 [Peer Reviewed Journal]COPYRIGHT 2013 Nature Publishing Group ;COPYRIGHT 2013 Nature Publishing Group ;Copyright Nature Publishing Group Nov 2013 ;ISSN: 1061-4036 ;ISSN: 1546-1718 ;EISSN: 1546-1718 ;DOI: 10.1038/ng.2795 ;PMID: 24097064Full text available |
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15 |
Material Type: Article
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Mendelian Randomization Study of ACLY and Cardiovascular DiseaseThe New England journal of medicine, 2019-03, Vol.380 (11), p.1033-1042 [Peer Reviewed Journal]Copyright © 2019 Massachusetts Medical Society. All rights reserved. ;Copyright © 2019 Massachusetts Medical Society. ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa1806747 ;PMID: 30865797Full text available |
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16 |
Material Type: Article
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Residual Cardiovascular Risk at Low LDL: Remnants, Lipoprotein(a), and InflammationClinical chemistry (Baltimore, Md.), 2021-01, Vol.67 (1), p.143-153 [Peer Reviewed Journal]American Association for Clinical Chemistry 2020. All rights reserved. For permissions, please email: journals.permissions@oup.com. 2020 ;American Association for Clinical Chemistry 2020. All rights reserved. For permissions, please email: journals.permissions@oup.com. ;COPYRIGHT 2021 American Association for Clinical Chemistry, Inc. ;ISSN: 0009-9147 ;EISSN: 1530-8561 ;DOI: 10.1093/clinchem/hvaa252 ;PMID: 33257928Full text available |
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17 |
Material Type: Article
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Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trialThe Lancet (British edition), 2014-01, Vol.383 (9911), p.60-68 [Peer Reviewed Journal]Elsevier Ltd ;2014 Elsevier Ltd ;2015 INIST-CNRS ;Copyright © 2014 Elsevier Ltd. All rights reserved. ;Copyright Elsevier Limited Jan 4, 2014 ;ISSN: 0140-6736 ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(13)61914-5 ;PMID: 24094767 ;CODEN: LANCAOFull text available |
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18 |
Material Type: Article
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Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control studyThe Lancet (British edition), 2013-04, Vol.381 (9874), p.1293-1301 [Peer Reviewed Journal]Elsevier Ltd ;2013 Elsevier Ltd ;2014 INIST-CNRS ;Copyright © 2013 Elsevier Ltd. All rights reserved. ;Copyright Elsevier Limited Apr 13, 2013 ;ISSN: 0140-6736 ;EISSN: 1474-547X ;DOI: 10.1016/S0140-6736(12)62127-8 ;PMID: 23433573 ;CODEN: LANCAOFull text available |
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19 |
Material Type: Article
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Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction riskNature genetics, 2014-04, Vol.46 (4), p.345-351 [Peer Reviewed Journal]COPYRIGHT 2014 Nature Publishing Group ;COPYRIGHT 2014 Nature Publishing Group ;Copyright Nature Publishing Group Apr 2014 ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/ng.2926 ;PMID: 24633158Full text available |
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20 |
Material Type: Article
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Low-Density Lipoprotein Cholesterol Lowering for the Primary Prevention of Cardiovascular Disease Among Men With Primary Elevations of Low-Density Lipoprotein Cholesterol Levels of 190 mg/dL or Above: Analyses From the WOSCOPS (West of Scotland Coronary Prevention Study) 5-Year Randomized Trial and 20-Year Observational Follow-UpCirculation (New York, N.Y.), 2017-11, Vol.136 (20), p.1878-1891 [Peer Reviewed Journal]2017 by the American College of Cardiology Foundation and the American Heart Association, Inc. ;2017 American Heart Association, Inc. ;ISSN: 0009-7322 ;EISSN: 1524-4539 ;DOI: 10.1161/CIRCULATIONAHA.117.027966 ;PMID: 28877913Full text available |