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Results 1 - 20 of 31  for All Library Resources

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1
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
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Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

Frontiers in chemistry, 2020-10, Vol.8, p.572885-572885 [Peer Reviewed Journal]

Copyright © 2020 Carino, Moraca, Fiorillo, Marchianò, Sepe, Biagioli, Finamore, Bozza, Francisci, Distrutti, Catalanotti, Zampella and Fiorucci. ;Copyright © 2020 Carino, Moraca, Fiorillo, Marchianò, Sepe, Biagioli, Finamore, Bozza, Francisci, Distrutti, Catalanotti, Zampella and Fiorucci. 2020 Carino, Moraca, Fiorillo, Marchianò, Sepe, Biagioli, Finamore, Bozza, Francisci, Distrutti, Catalanotti, Zampella and Fiorucci ;ISSN: 2296-2646 ;EISSN: 2296-2646 ;DOI: 10.3389/fchem.2020.572885 ;PMID: 33195060

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2
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists
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Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists

Molecules (Basel, Switzerland), 2023-03, Vol.28 (6), p.2840 [Peer Reviewed Journal]

2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2023 by the authors. 2023 ;ISSN: 1420-3049 ;EISSN: 1420-3049 ;DOI: 10.3390/molecules28062840 ;PMID: 36985811

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3
Phytochemical and Biological Studies of Nepeta asterotricha Rech. f. (Lamiaceae): Isolation of Nepetamoside
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Phytochemical and Biological Studies of Nepeta asterotricha Rech. f. (Lamiaceae): Isolation of Nepetamoside

Molecules (Basel, Switzerland), 2019-04, Vol.24 (9), p.1684 [Peer Reviewed Journal]

2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 1420-3049 ;EISSN: 1420-3049 ;DOI: 10.3390/molecules24091684 ;PMID: 31052163

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4
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists
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Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists

Scientific reports, 2016-01, Vol.6 (1), p.19008-19008, Article 19008 [Peer Reviewed Journal]

Copyright Nature Publishing Group Jan 2016 ;Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep19008 ;PMID: 26740187

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5
Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists
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Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists

ACS medicinal chemistry letters, 2019-04, Vol.10 (4), p.504-510 [Peer Reviewed Journal]

Copyright © 2019 American Chemical Society 2019 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/acsmedchemlett.8b00534 ;PMID: 30996787

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6
Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties
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Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties

Molecules (Basel, Switzerland), 2019-03, Vol.24 (6), p.1043 [Peer Reviewed Journal]

2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 1420-3049 ;EISSN: 1420-3049 ;DOI: 10.3390/molecules24061043 ;PMID: 30884797

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7
Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches
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Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches

Plants (Basel), 2022-06, Vol.11 (13), p.1671 [Peer Reviewed Journal]

2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2223-7747 ;EISSN: 2223-7747 ;DOI: 10.3390/plants11131671 ;PMID: 35807623

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8
Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”
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Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”

ACS omega, 2023-11, Vol.8 (47), p.45163-45163 [Peer Reviewed Journal]

2023 The Authors. Published by American Chemical Society 2023 The Authors ;ISSN: 2470-1343 ;EISSN: 2470-1343 ;DOI: 10.1021/acsomega.3c08464

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9
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands
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Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands

Scientific reports, 2016-07, Vol.6 (1), p.29320-29320, Article 29320 [Peer Reviewed Journal]

Copyright Nature Publishing Group Jul 2016 ;Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep29320 ;PMID: 27381677

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10
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests
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Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests

Biomolecules (Basel, Switzerland), 2021-10, Vol.11 (10), p.1490 [Peer Reviewed Journal]

2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 by the authors. 2021 ;ISSN: 2218-273X ;EISSN: 2218-273X ;DOI: 10.3390/biom11101490 ;PMID: 34680124

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11
Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands
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Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands

Journal of medicinal chemistry, 2014-10, Vol.57 (20), p.8477 [Peer Reviewed Journal]

EISSN: 1520-4804 ;DOI: 10.1021/jm501273r ;PMID: 25247751

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12
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor Agonists
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Article
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Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor Agonists

Molecules (Basel, Switzerland), 2023-03, Vol.28 (6) [Peer Reviewed Journal]

COPYRIGHT 2023 MDPI AG ;ISSN: 1420-3049 ;EISSN: 1420-3049 ;DOI: 10.3390/molecules28062840

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13
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis
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Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis

Biochemical pharmacology, 2024-05, Vol.223, p.116134 [Peer Reviewed Journal]

Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved. ;EISSN: 1873-2968 ;DOI: 10.1016/j.bcp.2024.116134 ;PMID: 38494064

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14
Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists
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Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists

Scientific reports, 2017-02, Vol.7 (1), p.43290-43290, Article 43290 [Peer Reviewed Journal]

Copyright © 2017, The Author(s) 2017 The Author(s) ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep43290 ;PMID: 28233865

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15
Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116
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Article
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Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116

Phytochemical analysis, 2019-09, Vol.30 (5), p.524 [Peer Reviewed Journal]

2019 John Wiley & Sons, Ltd. ;EISSN: 1099-1565 ;DOI: 10.1002/pca.2844 ;PMID: 31168900

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16
Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity
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Article
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Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity

Steroids, 2016-01, Vol.105, p.59 [Peer Reviewed Journal]

Copyright © 2015 Elsevier Inc. All rights reserved. ;EISSN: 1878-5867 ;DOI: 10.1016/j.steroids.2015.11.003 ;PMID: 26607331

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17
Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1
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Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1

Scientific reports, 2019-02, Vol.9 (1), p.2504-2504, Article 2504 [Peer Reviewed Journal]

This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-019-38840-z ;PMID: 30792450

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18
Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury
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Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury

ACS medicinal chemistry letters, 2019-04, Vol.10 (4), p.407-412 [Peer Reviewed Journal]

Copyright © 2018 American Chemical Society 2018 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/acsmedchemlett.8b00423 ;PMID: 30996771

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19
Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders
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Article
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Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders

ACS omega, 2023-02, Vol.8 (6), p.5983-5994 [Peer Reviewed Journal]

2023 The Authors. Published by American Chemical Society ;2023 The Authors. Published by American Chemical Society. ;2023 The Authors. Published by American Chemical Society 2023 The Authors ;ISSN: 2470-1343 ;EISSN: 2470-1343 ;DOI: 10.1021/acsomega.2c07907 ;PMID: 36816679

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20
Epoxide functionalization on cholane side chains in the identification of G-protein coupled bile acid receptor (GPBAR1) selective agonists
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Epoxide functionalization on cholane side chains in the identification of G-protein coupled bile acid receptor (GPBAR1) selective agonists

RSC advances, 2017-01, Vol.7 (52), p.32877-32885 [Peer Reviewed Journal]

ISSN: 2046-2069 ;EISSN: 2046-2069 ;DOI: 10.1039/C7RA04922F

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