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1 |
Material Type: Article
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Cerebral Cavernous Malformation: From Mechanism to TherapyCirculation research, 2021-06, Vol.129 (1), p.195-215 [Peer Reviewed Journal]ISSN: 0009-7330 ;EISSN: 1524-4571 ;DOI: 10.1161/circresaha.121.318174 ;PMID: 34166073Full text available |
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2 |
Material Type: Article
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PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanismNature (London), 2021-06, Vol.594 (7862), p.271-276 [Peer Reviewed Journal]COPYRIGHT 2021 Nature Publishing Group ;Copyright Nature Publishing Group Jun 10, 2021 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-021-03562-8 ;PMID: 33910229Full text available |
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3 |
Material Type: Article
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Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signallingNature (London), 2016-04, Vol.532 (7597), p.122-126 [Peer Reviewed Journal]COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Apr 7, 2016 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature17178 ;PMID: 27027284 ;CODEN: NATUASFull text available |
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4 |
Material Type: Article
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β1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformationsThe FASEB journal, 2022-12, Vol.36 (12), p.e22629-n/a [Peer Reviewed Journal]2022 Federation of American Societies for Experimental Biology. ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.202200907RR ;PMID: 36349990Full text available |
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5 |
Material Type: Article
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Immunothrombosis and vascular heterogeneity in cerebral cavernous malformationBlood, 2022-11, Vol.140 (20), p.2154-2169 [Peer Reviewed Journal]2022 The American Society of Hematology ;2022 by The American Society of Hematology. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved. ;ISSN: 0006-4971 ;ISSN: 1528-0020 ;EISSN: 1528-0020 ;DOI: 10.1182/blood.2021015350 ;PMID: 35981497Full text available |
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6 |
Material Type: Article
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Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytesNature communications, 2019-06, Vol.10 (1), p.2817-19, Article 2817 [Peer Reviewed Journal]2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-019-10643-w ;PMID: 31249304Full text available |
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7 |
Material Type: Article
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Cerebral cavernous malformations form an anticoagulant vascular domain in humans and miceBlood, 2019-01, Vol.133 (3), p.193-204 [Peer Reviewed Journal]2019 American Society of Hematology ;2019 by The American Society of Hematology. ;2019 by The American Society of Hematology 2019 ;ISSN: 0006-4971 ;EISSN: 1528-0020 ;DOI: 10.1182/blood-2018-06-856062 ;PMID: 30442679Full text available |
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8 |
Material Type: Article
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Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versicanThe Journal of experimental medicine, 2020-10, Vol.217 (10) [Peer Reviewed Journal]2020 Hong et al. ;2020 Hong et al. 2020 ;ISSN: 0022-1007 ;EISSN: 1540-9538 ;DOI: 10.1084/jem.20200140 ;PMID: 32648916Full text available |
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9 |
Material Type: Article
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Deregulated TGF-β/BMP Signaling in Vascular MalformationsCirculation research, 2017-09, Vol.121 (8), p.981-999 [Peer Reviewed Journal]2017 American Heart Association, Inc. ;Copyright Lippincott Williams & Wilkins Ovid Technologies Sep 29, 2017 ;ISSN: 0009-7330 ;ISSN: 1524-4571 ;EISSN: 1524-4571 ;DOI: 10.1161/CIRCRESAHA.117.309930 ;PMID: 28963191Full text available |
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10 |
Material Type: Article
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Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformationNature medicine, 2016-09, Vol.22 (9), p.1033-1042 [Peer Reviewed Journal]COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Sep 2016 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.4169 ;PMID: 27548575Full text available |
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11 |
Material Type: Article
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Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM ProteinsDevelopmental cell, 2015-01, Vol.32 (2), p.181-190 [Peer Reviewed Journal]2015 Elsevier Inc. ;Copyright © 2015 Elsevier Inc. All rights reserved. ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 1534-5807 ;EISSN: 1878-1551 ;DOI: 10.1016/j.devcel.2014.12.016 ;PMID: 25625207Full text available |
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12 |
Material Type: Article
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Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformationsThe Journal of experimental medicine, 2017-11, Vol.214 (11), p.3331-3346 [Peer Reviewed Journal]2017 Lopez-Ramirez et al. ;Copyright Rockefeller University Press Nov 6, 2017 ;2017 Lopez-Ramirez et al. 2017 ;ISSN: 0022-1007 ;EISSN: 1540-9538 ;DOI: 10.1084/jem.20171178 ;PMID: 28970240Full text available |
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13 |
Material Type: Article
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Connexin 43 gap junctions contribute to brain endothelial barrier hyperpermeability in familial cerebral cavernous malformations type III by modulating tight junction structureThe FASEB journal, 2018-05, Vol.32 (5), p.2615-2629 [Peer Reviewed Journal]FASEB ;FASEB 2018 FASEB ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.201700699R ;PMID: 29295866Full text available |
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14 |
Material Type: Article
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Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal modelsThe Journal of clinical investigation, 2021-02, Vol.131 (3) [Peer Reviewed Journal]2021 American Society for Clinical Investigation 2021 American Society for Clinical Investigation ;ISSN: 0021-9738 ;EISSN: 1558-8238 ;DOI: 10.1172/JCI144893 ;PMID: 33301422Full text available |
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15 |
Material Type: Article
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Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse modelNature communications, 2021-01, Vol.12 (1), p.504-504, Article 504 [Peer Reviewed Journal]The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2021 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-020-20774-0 ;PMID: 33495460Full text available |
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16 |
Material Type: Article
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Deciphering impact of single nucleotide polymorphisms on cotranscriptional modification in CCM gene mRNAsAmerican Journal of Physiology: Cell Physiology, 2022-10, Vol.323 (4), p.C1274-C1284 [Peer Reviewed Journal]ISSN: 0363-6143 ;EISSN: 1522-1563 ;DOI: 10.1152/ajpcell.00279.2022 ;PMID: 36094437Full text available |
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17 |
Material Type: Article
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Inflammation and neutrophil extracellular traps in cerebral cavernous malformationCellular and molecular life sciences : CMLS, 2022-04, Vol.79 (4), p.206-206, Article 206 [Peer Reviewed Journal]The Author(s) 2022. corrected publication 2022 ;2022. The Author(s). ;The Author(s) 2022. corrected publication 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2022, corrected publication 2022 ;ISSN: 1420-682X ;ISSN: 1420-9071 ;EISSN: 1420-9071 ;DOI: 10.1007/s00018-022-04224-2 ;PMID: 35333979Full text available |
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18 |
Material Type: Article
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KLF4 is a key determinant in the development and progression of cerebral cavernous malformationsEMBO molecular medicine, 2016-01, Vol.8 (1), p.6-24 [Peer Reviewed Journal]2015 The Authors. Published under the terms of the CC BY 4.0 license ;2015 The Authors. Published under the terms of the CC BY 4.0 license. ;ISSN: 1757-4676 ;ISSN: 1757-4684 ;EISSN: 1757-4684 ;DOI: 10.15252/emmm.201505433 ;PMID: 26612856Full text available |
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19 |
Material Type: Article
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KRIT1: A Traffic Warden at the Busy Crossroads Between Redox Signaling and the Pathogenesis of Cerebral Cavernous Malformation DiseaseAntioxidants & redox signaling, 2023-03, Vol.38 (7-9), p.496-528 [Peer Reviewed Journal]2023, Mary Ann Liebert, Inc., publishers ;Copyright Mary Ann Liebert, Inc. Mar 1, 2023 ;Copyright 2023, Mary Ann Liebert, Inc., publishers 2023 Mary Ann Liebert, Inc., publishers ;ISSN: 1523-0864 ;EISSN: 1557-7716 ;DOI: 10.1089/ars.2021.0263 ;PMID: 36047808Full text available |
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20 |
Material Type: Article
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Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout miceProceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.8421-8426 [Peer Reviewed Journal]Copyright National Academy of Sciences Jul 7, 2015 ;ISSN: 0027-8424 ;ISSN: 1091-6490 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1501352112 ;PMID: 26109568Full text available |