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1
Cerebral Cavernous Malformation: From Mechanism to Therapy
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Cerebral Cavernous Malformation: From Mechanism to Therapy

Circulation research, 2021-06, Vol.129 (1), p.195-215 [Peer Reviewed Journal]

ISSN: 0009-7330 ;EISSN: 1524-4571 ;DOI: 10.1161/circresaha.121.318174 ;PMID: 34166073

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2
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism
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PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism

Nature (London), 2021-06, Vol.594 (7862), p.271-276 [Peer Reviewed Journal]

COPYRIGHT 2021 Nature Publishing Group ;Copyright Nature Publishing Group Jun 10, 2021 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-021-03562-8 ;PMID: 33910229

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3
Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations
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Article
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Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations

The Journal of experimental medicine, 2017-11, Vol.214 (11), p.3331-3346 [Peer Reviewed Journal]

2017 Lopez-Ramirez et al. ;Copyright Rockefeller University Press Nov 6, 2017 ;2017 Lopez-Ramirez et al. 2017 ;ISSN: 0022-1007 ;EISSN: 1540-9538 ;DOI: 10.1084/jem.20171178 ;PMID: 28970240

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4
Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model
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Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model

Nature communications, 2021-01, Vol.12 (1), p.504-504, Article 504 [Peer Reviewed Journal]

The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2021 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-020-20774-0 ;PMID: 33495460

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5
Inflammation and neutrophil extracellular traps in cerebral cavernous malformation
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Inflammation and neutrophil extracellular traps in cerebral cavernous malformation

Cellular and molecular life sciences : CMLS, 2022-04, Vol.79 (4), p.206-206, Article 206 [Peer Reviewed Journal]

The Author(s) 2022. corrected publication 2022 ;2022. The Author(s). ;The Author(s) 2022. corrected publication 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2022, corrected publication 2022 ;ISSN: 1420-682X ;ISSN: 1420-9071 ;EISSN: 1420-9071 ;DOI: 10.1007/s00018-022-04224-2 ;PMID: 35333979

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6
KLF4 is a key determinant in the development and progression of cerebral cavernous malformations
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Article
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KLF4 is a key determinant in the development and progression of cerebral cavernous malformations

EMBO molecular medicine, 2016-01, Vol.8 (1), p.6-24 [Peer Reviewed Journal]

2015 The Authors. Published under the terms of the CC BY 4.0 license ;2015 The Authors. Published under the terms of the CC BY 4.0 license. ;ISSN: 1757-4676 ;ISSN: 1757-4684 ;EISSN: 1757-4684 ;DOI: 10.15252/emmm.201505433 ;PMID: 26612856

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7
KRIT1: A Traffic Warden at the Busy Crossroads Between Redox Signaling and the Pathogenesis of Cerebral Cavernous Malformation Disease
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KRIT1: A Traffic Warden at the Busy Crossroads Between Redox Signaling and the Pathogenesis of Cerebral Cavernous Malformation Disease

Antioxidants & redox signaling, 2023-03, Vol.38 (7-9), p.496-528 [Peer Reviewed Journal]

2023, Mary Ann Liebert, Inc., publishers ;Copyright Mary Ann Liebert, Inc. Mar 1, 2023 ;Copyright 2023, Mary Ann Liebert, Inc., publishers 2023 Mary Ann Liebert, Inc., publishers ;ISSN: 1523-0864 ;EISSN: 1557-7716 ;DOI: 10.1089/ars.2021.0263 ;PMID: 36047808

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8
Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice
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Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.8421-8426 [Peer Reviewed Journal]

Copyright National Academy of Sciences Jul 7, 2015 ;ISSN: 0027-8424 ;ISSN: 1091-6490 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1501352112 ;PMID: 26109568

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9
GCKIII (Germinal Center Kinase III) Kinases STK24 and STK25 (Serine/Threonine Kinase 24 and 25) Inhibit Cavernoma Development
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GCKIII (Germinal Center Kinase III) Kinases STK24 and STK25 (Serine/Threonine Kinase 24 and 25) Inhibit Cavernoma Development

Stroke (1970), 2022-03, Vol.53 (3), p.976-986 [Peer Reviewed Journal]

ISSN: 0039-2499 ;EISSN: 1524-4628 ;DOI: 10.1161/STROKEAHA.121.036940 ;PMID: 35130716

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10
Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling
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Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (28), p.12640-12645 [Peer Reviewed Journal]

copyright © 1993-2008 National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences Jul 13, 2010 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1000132107 ;PMID: 20616044

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11
Phenotypic characterization of murine models of cerebral cavernous malformations
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Article
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Phenotypic characterization of murine models of cerebral cavernous malformations

Laboratory investigation, 2019-03, Vol.99 (3), p.319-330 [Peer Reviewed Journal]

2018 United States & Canadian Academy of Pathology ;Copyright Nature Publishing Group Mar 2019 ;ISSN: 0023-6837 ;EISSN: 1530-0307 ;DOI: 10.1038/s41374-018-0030-y ;PMID: 29946133

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12
VEGF signalling enhances lesion burden in KRIT1 deficient mice
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Article
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VEGF signalling enhances lesion burden in KRIT1 deficient mice

Journal of cellular and molecular medicine, 2020-01, Vol.24 (1), p.632-639 [Peer Reviewed Journal]

2019 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for cellular and Molecular Medicine and John Wiley & Sons Ltd ;2019 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for cellular and Molecular Medicine and John Wiley & Sons Ltd. ;2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1582-1838 ;EISSN: 1582-4934 ;DOI: 10.1111/jcmm.14773 ;PMID: 31746130

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13
Loss of cerebral cavernous malformation 3 (Ccm3) in neuroglia leads to CCM and vascular pathology
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Loss of cerebral cavernous malformation 3 (Ccm3) in neuroglia leads to CCM and vascular pathology

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (9), p.3737-3742 [Peer Reviewed Journal]

Copyright National Academy of Sciences Mar 1, 2011 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1012617108 ;PMID: 21321212

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14
Building Blood Vessels-One Rho GTPase at a Time
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Article
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Building Blood Vessels-One Rho GTPase at a Time

Cells (Basel, Switzerland), 2019-06, Vol.8 (6), p.545 [Peer Reviewed Journal]

2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells8060545 ;PMID: 31174284

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15
Concepts and hypothesis: integrin cytoplasmic domain-associated protein-1 (ICAP-1) as a potential player in cerebral cavernous malformation
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Article
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Concepts and hypothesis: integrin cytoplasmic domain-associated protein-1 (ICAP-1) as a potential player in cerebral cavernous malformation

Journal of neurology, 2013, Vol.260 (1), p.10-19 [Peer Reviewed Journal]

Springer-Verlag 2012 ;Springer-Verlag 2012. ;ISSN: 0340-5354 ;EISSN: 1432-1459 ;DOI: 10.1007/s00415-012-6567-6 ;PMID: 22711159

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