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1
Cerebral Cavernous Malformation: From Mechanism to Therapy
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Cerebral Cavernous Malformation: From Mechanism to Therapy

Circulation research, 2021-06, Vol.129 (1), p.195-215 [Peer Reviewed Journal]

ISSN: 0009-7330 ;EISSN: 1524-4571 ;DOI: 10.1161/circresaha.121.318174 ;PMID: 34166073

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2
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism
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PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism

Nature (London), 2021-06, Vol.594 (7862), p.271-276 [Peer Reviewed Journal]

COPYRIGHT 2021 Nature Publishing Group ;Copyright Nature Publishing Group Jun 10, 2021 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-021-03562-8 ;PMID: 33910229

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3
Endothelial TLR4 and the microbiome drive cerebral cavernous malformations
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Endothelial TLR4 and the microbiome drive cerebral cavernous malformations

Nature (London), 2017-05, Vol.545 (7654), p.305-310 [Peer Reviewed Journal]

COPYRIGHT 2017 Nature Publishing Group ;COPYRIGHT 2017 Nature Publishing Group ;Copyright Nature Publishing Group May 18, 2017 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature22075 ;PMID: 28489816

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4
EndMT contributes to the onset and progression of cerebral cavernous malformations
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EndMT contributes to the onset and progression of cerebral cavernous malformations

Nature (London), 2013-06, Vol.498 (7455), p.492-496 [Peer Reviewed Journal]

COPYRIGHT 2013 Nature Publishing Group ;COPYRIGHT 2013 Nature Publishing Group ;Copyright Nature Publishing Group Jun 27, 2013 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature12207 ;PMID: 23748444 ;CODEN: NATUAS

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5
Endothelial cell clonal expansion in the development of cerebral cavernous malformations
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Endothelial cell clonal expansion in the development of cerebral cavernous malformations

Nature communications, 2019-06, Vol.10 (1), p.2761-16, Article 2761 [Peer Reviewed Journal]

2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-019-10707-x ;PMID: 31235698

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6
Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes
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Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes

Nature communications, 2019-06, Vol.10 (1), p.2817-19, Article 2817 [Peer Reviewed Journal]

2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-019-10643-w ;PMID: 31249304

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7
Cerebral Cavernous Malformation: What a Practicing Clinician Should Know
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Cerebral Cavernous Malformation: What a Practicing Clinician Should Know

Mayo Clinic proceedings, 2020-09, Vol.95 (9), p.2005-2020 [Peer Reviewed Journal]

2019 Mayo Foundation for Medical Education and Research ;Copyright © 2019 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved. ;COPYRIGHT 2020 Elsevier, Inc. ;Copyright Mayo Foundation for Medical Education and Research Sep 2020 ;ISSN: 0025-6196 ;EISSN: 1942-5546 ;DOI: 10.1016/j.mayocp.2019.11.005 ;PMID: 32605781

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8
Clinical presentation, natural history and outcomes of intramedullary spinal cord cavernous malformations
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Clinical presentation, natural history and outcomes of intramedullary spinal cord cavernous malformations

Journal of neurology, neurosurgery and psychiatry, 2019-06, Vol.90 (6), p.695-703 [Peer Reviewed Journal]

Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ. ;2019 Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ. ;ISSN: 0022-3050 ;EISSN: 1468-330X ;DOI: 10.1136/jnnp-2018-319553 ;PMID: 30760644

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9
The natural history of intracranial cavernous malformations
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The natural history of intracranial cavernous malformations

Neurosurgical focus, 2011-06, Vol.30 (6), p.E24-E24 [Peer Reviewed Journal]

ISSN: 1092-0684 ;EISSN: 1092-0684 ;DOI: 10.3171/2011.3.focus1165 ;PMID: 21631226

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10
Molecular Biomarkers and Drug Targets in Brain Arteriovenous and Cavernous Malformations: Where Are We?
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Molecular Biomarkers and Drug Targets in Brain Arteriovenous and Cavernous Malformations: Where Are We?

Stroke (1970), 2022-01, Vol.53 (1), p.279-289 [Peer Reviewed Journal]

ISSN: 0039-2499 ;EISSN: 1524-4628 ;DOI: 10.1161/strokeaha.121.035654 ;PMID: 34784742

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11
Connexin 43 gap junctions contribute to brain endothelial barrier hyperpermeability in familial cerebral cavernous malformations type III by modulating tight junction structure
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Connexin 43 gap junctions contribute to brain endothelial barrier hyperpermeability in familial cerebral cavernous malformations type III by modulating tight junction structure

The FASEB journal, 2018-05, Vol.32 (5), p.2615-2629 [Peer Reviewed Journal]

FASEB ;FASEB 2018 FASEB ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.201700699R ;PMID: 29295866

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12
KLF4 is a key determinant in the development and progression of cerebral cavernous malformations
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KLF4 is a key determinant in the development and progression of cerebral cavernous malformations

EMBO molecular medicine, 2016-01, Vol.8 (1), p.6-24 [Peer Reviewed Journal]

2015 The Authors. Published under the terms of the CC BY 4.0 license ;2015 The Authors. Published under the terms of the CC BY 4.0 license. ;ISSN: 1757-4676 ;ISSN: 1757-4684 ;EISSN: 1757-4684 ;DOI: 10.15252/emmm.201505433 ;PMID: 26612856

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13
Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity
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Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

The Journal of experimental medicine, 2010-04, Vol.207 (4), p.881-896 [Peer Reviewed Journal]

2010 Stockton et al. 2010 ;ISSN: 0022-1007 ;EISSN: 1540-9538 ;DOI: 10.1084/jem.20091258 ;PMID: 20308363

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14
Endothelial Cells Lining Sporadic Cerebral Cavernous Malformation Cavernomas Undergo Endothelial-to-Mesenchymal Transition
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Article
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Endothelial Cells Lining Sporadic Cerebral Cavernous Malformation Cavernomas Undergo Endothelial-to-Mesenchymal Transition

Stroke (1970), 2016-03, Vol.47 (3), p.886-890 [Peer Reviewed Journal]

2016 American Heart Association, Inc. ;ISSN: 0039-2499 ;ISSN: 1524-4628 ;EISSN: 1524-4628 ;DOI: 10.1161/strokeaha.115.011867 ;PMID: 26839352

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15
The trajectory of the medial longitudinal fasciculus in the human brain: A diffusion imaging‐based tractography study
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The trajectory of the medial longitudinal fasciculus in the human brain: A diffusion imaging‐based tractography study

Human brain mapping, 2021-12, Vol.42 (18), p.6070-6086 [Peer Reviewed Journal]

2021 The Authors. published by Wiley Periodicals LLC. ;2021 The Authors. Human Brain Mapping published by Wiley Periodicals LLC. ;2021. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1065-9471 ;EISSN: 1097-0193 ;DOI: 10.1002/hbm.25670 ;PMID: 34597450

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16
CCM1 regulates vascular-lumen organization by inducing endothelial polarity
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Article
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CCM1 regulates vascular-lumen organization by inducing endothelial polarity

Journal of cell science, 2010-04, Vol.123 (7), p.1073-1080 [Peer Reviewed Journal]

ISSN: 0021-9533 ;EISSN: 1477-9137 ;DOI: 10.1242/jcs.059329 ;PMID: 20332120

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17
Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling
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Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (28), p.12640-12645 [Peer Reviewed Journal]

copyright © 1993-2008 National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences Jul 13, 2010 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1000132107 ;PMID: 20616044

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18
Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology
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Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology

Cellular and molecular life sciences : CMLS, 2014-05, Vol.71 (10), p.1881-1892 [Peer Reviewed Journal]

Springer Basel 2013 ;Springer Basel 2014 ;Springer Basel 2013 2013 ;ISSN: 1420-682X ;EISSN: 1420-9071 ;DOI: 10.1007/s00018-013-1532-9 ;PMID: 24287896

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19
Genotype-phenotype correlations in cerebral cavernous malformations patients
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Genotype-phenotype correlations in cerebral cavernous malformations patients

Annals of neurology, 2006-11, Vol.60 (5), p.550-556 [Peer Reviewed Journal]

Copyright © 2006 American Neurological Association ;2007 INIST-CNRS ;ISSN: 0364-5134 ;EISSN: 1531-8249 ;DOI: 10.1002/ana.20947 ;PMID: 17041941 ;CODEN: ANNED3

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20
Rho Kinase Inhibition Rescues the Endothelial Cell Cerebral Cavernous Malformation Phenotype
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Rho Kinase Inhibition Rescues the Endothelial Cell Cerebral Cavernous Malformation Phenotype

The Journal of biological chemistry, 2010-04, Vol.285 (16), p.11760-11764 [Peer Reviewed Journal]

2010 © 2010 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2010 by The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.C109.097220 ;PMID: 20181950

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