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1
Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis
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Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis

PLoS genetics, 2015-11, Vol.11 (11), p.e1005553-e1005553 [Peer Reviewed Journal]

COPYRIGHT 2015 Public Library of Science ;COPYRIGHT 2015 Public Library of Science ;2015 Kraus et al 2015 Kraus et al ;2015 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Kraus WE, Muoio DM, Stevens R, Craig D, Bain JR, Grass E, et al. (2015) Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis. PLoS Genet 11(11): e1005553. doi:10.1371/journal.pgen.1005553 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1005553 ;PMID: 26540294

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2
The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets
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The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets

PLoS genetics, 2016-12, Vol.12 (12), p.e1006466-e1006466 [Peer Reviewed Journal]

2016 Keller et al 2016 Keller et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1006466 ;PMID: 27935966

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3
Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes
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Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes

PLoS genetics, 2012-02, Vol.8 (2), p.e1002505-e1002505 [Peer Reviewed Journal]

2012 Min et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Min JL, Nicholson G, Halgrimsdottir I, Almstrup K, Petri A, et al. (2012) Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes. PLoS Genet 8(2): e1002505. doi:10.1371/journal.pgen.1002505 ;Min et al. 2012 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1002505 ;PMID: 22383892

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4
Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis
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Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

Cell, 2015-12, Vol.163 (7), p.1585-1595 [Peer Reviewed Journal]

2015 Elsevier Inc. ;Copyright © 2015 Elsevier Inc. All rights reserved. ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2015.11.055 ;PMID: 26687352

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5
Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort
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Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort

Genome Biology, 2017-04, Vol.18 (1), p.70-14, Article 70 [Peer Reviewed Journal]

2017. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s). 2017 ;ISSN: 1474-760X ;ISSN: 1474-7596 ;EISSN: 1474-760X ;DOI: 10.1186/s13059-017-1194-2 ;PMID: 28407784

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6
The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases
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The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases

Journal of lipid research, 2017-03, Vol.58 (3), p.481-493 [Peer Reviewed Journal]

2017 © 2017 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;Copyright Journal of Lipid Research Mar 2017 ;ISSN: 0022-2275 ;EISSN: 1539-7262 ;DOI: 10.1194/jlr.O072629 ;PMID: 28119442

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7
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk
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Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

Cell, 2016-03, Vol.165 (1), p.111-124 [Peer Reviewed Journal]

2016 Elsevier Inc. ;Copyright © 2016 Elsevier Inc. All rights reserved. ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2016.02.011 ;PMID: 26972052

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8
Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice
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Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice

Scientific reports, 2021-01, Vol.11 (1), p.518-11, Article 518 [Peer Reviewed Journal]

The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2021 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-020-80063-0 ;PMID: 33436815

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9
Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB
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Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB

Journal of the American Heart Association, 2016-02, Vol.5 (2), p.n/a [Peer Reviewed Journal]

2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. ;ISSN: 2047-9980 ;EISSN: 2047-9980 ;DOI: 10.1161/JAHA.115.002767 ;PMID: 26903003

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10
Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance
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Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance

Diabetes (New York, N.Y.), 2019-09, Vol.68 (9), p.1730-1746 [Peer Reviewed Journal]

2019 by the American Diabetes Association. ;Copyright American Diabetes Association Sep 1, 2019 ;2019 by the American Diabetes Association. 2019 ;ISSN: 0012-1797 ;EISSN: 1939-327X ;DOI: 10.2337/db18-0927 ;PMID: 31167878

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11
Sex differences and hormonal effects on gut microbiota composition in mice
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Sex differences and hormonal effects on gut microbiota composition in mice

Gut microbes, 2016-07, Vol.7 (4), p.313-322 [Peer Reviewed Journal]

2016 The Author(s). Published with license by Taylor & Francis Group, LLC © Elin Org, Margarete Mehrabian, Brian W. Parks, Petia Shipkova, Xiaoqin Liu, Thomas A. Drake, and Aldons J. Lusis 2016 ;2016 The Author(s). Published with license by Taylor & Francis Group, LLC 2016 The Author(s) ;ISSN: 1949-0976 ;EISSN: 1949-0984 ;DOI: 10.1080/19490976.2016.1203502 ;PMID: 27355107

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12
Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice
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Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

Cell metabolism, 2013-01, Vol.17 (1), p.141-152 [Peer Reviewed Journal]

2013 Elsevier Inc. ;Copyright © 2013 Elsevier Inc. All rights reserved. ;2013 Elsevier Inc. All rights reserved. 2013 ;ISSN: 1550-4131 ;EISSN: 1932-7420 ;DOI: 10.1016/j.cmet.2012.12.007 ;PMID: 23312289

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13
Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies: A Scientific Statement From the American Heart Association
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Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies: A Scientific Statement From the American Heart Association

Arteriosclerosis, thrombosis, and vascular biology, 2017-09, Vol.37 (9), p.e131-e157 [Peer Reviewed Journal]

2017 American Heart Association, Inc. ;ISSN: 1079-5642 ;EISSN: 1524-4636 ;DOI: 10.1161/ATV.0000000000000062 ;PMID: 28729366

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14
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration
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Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration

Nature genetics, 2017-09, Vol.49 (9), p.1346-1353 [Peer Reviewed Journal]

COPYRIGHT 2017 Nature Publishing Group ;COPYRIGHT 2017 Nature Publishing Group ;Copyright Nature Publishing Group Sep 2017 ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/ng.3929 ;PMID: 28783163

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15
Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential
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Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential

Nature medicine, 2018-09, Vol.24 (9), p.1407-1417 [Peer Reviewed Journal]

COPYRIGHT 2018 Nature Publishing Group ;COPYRIGHT 2018 Nature Publishing Group ;Copyright Nature Publishing Group Sep 2018 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/s41591-018-0128-1 ;PMID: 30082863

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16
Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA
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Article
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Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA

Nature medicine, 2018-03, Vol.24 (3), p.304-312 [Peer Reviewed Journal]

COPYRIGHT 2018 Nature Publishing Group ;COPYRIGHT 2018 Nature Publishing Group ;Copyright Nature Publishing Group Mar 2018 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.4479 ;PMID: 29431742

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17
γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L-Carnitine to TMAO
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γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L-Carnitine to TMAO

Cell metabolism, 2014-11, Vol.20 (5), p.799-812 [Peer Reviewed Journal]

2014 Elsevier Inc. ;Copyright © 2014 Elsevier Inc. All rights reserved. ;ISSN: 1550-4131 ;EISSN: 1932-7420 ;DOI: 10.1016/j.cmet.2014.10.006 ;PMID: 25440057

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18
Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation
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Article
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Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

Cell metabolism, 2013-01, Vol.17 (1), p.49-60 [Peer Reviewed Journal]

2013 Elsevier Inc. ;Copyright © 2013 Elsevier Inc. All rights reserved. ;2012 Elsevier Inc. All rights reserved. 2012 ;ISSN: 1550-4131 ;EISSN: 1932-7420 ;DOI: 10.1016/j.cmet.2012.12.011 ;PMID: 23312283

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19
Genetic Architecture of Insulin Resistance in the Mouse
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Article
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Genetic Architecture of Insulin Resistance in the Mouse

Cell metabolism, 2015-02, Vol.21 (2), p.334-347 [Peer Reviewed Journal]

2015 Elsevier Inc. ;Copyright © 2015 Elsevier Inc. All rights reserved. ;2015 Elsevier Inc. All rights reserved. 2015 ;ISSN: 1550-4131 ;EISSN: 1932-7420 ;DOI: 10.1016/j.cmet.2015.01.002 ;PMID: 25651185

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20
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis
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Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

Nature medicine, 2013-05, Vol.19 (5), p.576-585 [Peer Reviewed Journal]

COPYRIGHT 2013 Nature Publishing Group ;COPYRIGHT 2013 Nature Publishing Group ;Copyright Nature Publishing Group May 2013 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.3145 ;PMID: 23563705

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