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1
The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions
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The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions

Nutrients, 2019-08, Vol.11 (8), p.1820 [Peer Reviewed Journal]

2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu11081820 ;PMID: 31394746

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2
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy
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The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy

The FASEB journal, 2021-01, Vol.35 (1), p.e21271-n/a [Peer Reviewed Journal]

2020 Federation of American Societies for Experimental Biology ;2020 Federation of American Societies for Experimental Biology. ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.202001386R ;PMID: 33368684

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3
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
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Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH

Scientific reports, 2023-01, Vol.13 (1), p.1602-1602, Article 1602 [Peer Reviewed Journal]

2023. The Author(s). ;The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2023 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-023-28647-4 ;PMID: 36709356

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4
Bile Acids Activated Receptors in Inflammatory Bowel Disease
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Bile Acids Activated Receptors in Inflammatory Bowel Disease

Cells (Basel, Switzerland), 2021-05, Vol.10 (6), p.1281 [Peer Reviewed Journal]

2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 by the authors. 2021 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells10061281 ;PMID: 34064187

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5
Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation
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Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation

Nutrients, 2020-06, Vol.12 (7), p.1945 [Peer Reviewed Journal]

2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 by the authors. 2020 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu12071945 ;PMID: 32629887

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6
Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
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Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis

Frontiers in oncology, 2022-06, Vol.12, p.939969-939969 [Peer Reviewed Journal]

Copyright © 2022 Di Giorgio, Marchianò, Marino, Biagioli, Roselli, Bordoni, Bellini, Urbani, Zampella, Distrutti, Donini, Graziosi and Fiorucci 2022 Di Giorgio, Marchianò, Marino, Biagioli, Roselli, Bordoni, Bellini, Urbani, Zampella, Distrutti, Donini, Graziosi and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2022.939969 ;PMID: 35847866

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7
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
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Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

Nutrients, 2019-05, Vol.11 (5), p.1132 [Peer Reviewed Journal]

2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu11051132 ;PMID: 31117231

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8
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
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Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma

Frontiers in oncology, 2023-03, Vol.13, p.1140730-1140730 [Peer Reviewed Journal]

Copyright © 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci. ;Copyright © 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2023.1140730 ;PMID: 36998446

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9
Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease
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Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease

Journal of the American Heart Association, 2023-12, Vol.12 (23), p.e031241-e031241 [Peer Reviewed Journal]

2023 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. ;ISSN: 2047-9980 ;EISSN: 2047-9980 ;DOI: 10.1161/JAHA.123.031241 ;PMID: 37996988

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10
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease
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Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease

Frontiers in pharmacology, 2022-04, Vol.13, p.858137-858137 [Peer Reviewed Journal]

Copyright © 2022 Fiorucci, Rapacciuolo, Fiorillo, Roselli, Marchianò, Di Giorgio, Bordoni, Bellini, Cassiano, Conflitti, Catalanotti, Limongelli, Sepe, Biagioli and Zampella. 2022 Fiorucci, Rapacciuolo, Fiorillo, Roselli, Marchianò, Di Giorgio, Bordoni, Bellini, Cassiano, Conflitti, Catalanotti, Limongelli, Sepe, Biagioli and Zampella ;ISSN: 1663-9812 ;EISSN: 1663-9812 ;DOI: 10.3389/fphar.2022.858137 ;PMID: 35559268

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11
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer
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The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer

Cellular oncology (Dordrecht), 2024-04, Vol.47 (2), p.695-710

The Author(s) 2023 ;ISSN: 2211-3428 ;EISSN: 2211-3436 ;DOI: 10.1007/s13402-023-00893-8

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12
GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against Colitis
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GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against Colitis

ACS medicinal chemistry letters, 2020-05, Vol.11 (5), p.818-824 [Peer Reviewed Journal]

Copyright © 2020 American Chemical Society. ;Copyright © 2020 American Chemical Society 2020 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/acsmedchemlett.9b00636 ;PMID: 32435390

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13
Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”
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Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”

ACS omega, 2023-11, Vol.8 (47), p.45163-45163 [Peer Reviewed Journal]

2023 The Authors. Published by American Chemical Society 2023 The Authors ;ISSN: 2470-1343 ;EISSN: 2470-1343 ;DOI: 10.1021/acsomega.3c08464

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14
GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
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GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation

Cells (Basel, Switzerland), 2022-04, Vol.11 (7), p.1187 [Peer Reviewed Journal]

2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells11071187 ;PMID: 35406751

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15
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
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Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma

Cells (Basel, Switzerland), 2022-11, Vol.11 (21), p.3482 [Peer Reviewed Journal]

COPYRIGHT 2022 MDPI AG ;2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells11213482 ;PMID: 36359879

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16
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity
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The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity

The Journal of immunology (1950), 2020-05, Vol.204 (9), p.2535-2551 [Peer Reviewed Journal]

Copyright © 2020 by The American Association of Immunologists, Inc. ;ISSN: 0022-1767 ;EISSN: 1550-6606 ;DOI: 10.4049/jimmunol.1901427 ;PMID: 32213564

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17
Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling
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Article
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Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling

The FASEB journal, 2022-01, Vol.36 (1), p.e22060-n/a [Peer Reviewed Journal]

2021 The Authors. published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology. ;2021 The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology. ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.202101397R ;PMID: 34862975

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18
GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis
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GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis

Cellular and molecular gastroenterology and hepatology, 2019-01, Vol.8 (3), p.447-473 [Peer Reviewed Journal]

The Authors ;2019 The Authors ;Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved. ;2019 The Authors 2019 ;ISSN: 2352-345X ;EISSN: 2352-345X ;DOI: 10.1016/j.jcmgh.2019.06.003 ;PMID: 31226434

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19
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT 1 R Modulator for the Treatment of Metabolic Fatty Liver Disease
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Article
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Discovery of a Potent and Orally Active Dual GPBAR1/CysLT 1 R Modulator for the Treatment of Metabolic Fatty Liver Disease

Frontiers in pharmacology, 2022, Vol.13, p.858137 [Peer Reviewed Journal]

Copyright © 2022 Fiorucci, Rapacciuolo, Fiorillo, Roselli, Marchianò, Di Giorgio, Bordoni, Bellini, Cassiano, Conflitti, Catalanotti, Limongelli, Sepe, Biagioli and Zampella. ;ISSN: 1663-9812 ;EISSN: 1663-9812 ;PMID: 35559268

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20
Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders
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Article
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Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders

ACS omega, 2023-02, Vol.8 (6), p.5983-5994 [Peer Reviewed Journal]

2023 The Authors. Published by American Chemical Society ;2023 The Authors. Published by American Chemical Society. ;2023 The Authors. Published by American Chemical Society 2023 The Authors ;ISSN: 2470-1343 ;EISSN: 2470-1343 ;DOI: 10.1021/acsomega.2c07907 ;PMID: 36816679

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