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The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic DysfunctionsNutrients, 2019-08, Vol.11 (8), p.1820 [Peer Reviewed Journal]2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu11081820 ;PMID: 31394746Full text available |
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The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagyThe FASEB journal, 2021-01, Vol.35 (1), p.e21271-n/a [Peer Reviewed Journal]2020 Federation of American Societies for Experimental Biology ;2020 Federation of American Societies for Experimental Biology. ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.202001386R ;PMID: 33368684Full text available |
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Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASHScientific reports, 2023-01, Vol.13 (1), p.1602-1602, Article 1602 [Peer Reviewed Journal]2023. The Author(s). ;The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2023 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-023-28647-4 ;PMID: 36709356Full text available |
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Bile Acids Activated Receptors in Inflammatory Bowel DiseaseCells (Basel, Switzerland), 2021-05, Vol.10 (6), p.1281 [Peer Reviewed Journal]2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 by the authors. 2021 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells10061281 ;PMID: 34064187Full text available |
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Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal InflammationNutrients, 2020-06, Vol.12 (7), p.1945 [Peer Reviewed Journal]2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 by the authors. 2020 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu12071945 ;PMID: 32629887Full text available |
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Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor PrognosisFrontiers in oncology, 2022-06, Vol.12, p.939969-939969 [Peer Reviewed Journal]Copyright © 2022 Di Giorgio, Marchianò, Marino, Biagioli, Roselli, Bordoni, Bellini, Urbani, Zampella, Distrutti, Donini, Graziosi and Fiorucci 2022 Di Giorgio, Marchianò, Marino, Biagioli, Roselli, Bordoni, Bellini, Urbani, Zampella, Distrutti, Donini, Graziosi and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2022.939969 ;PMID: 35847866Full text available |
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Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets FormationNutrients, 2019-05, Vol.11 (5), p.1132 [Peer Reviewed Journal]2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu11051132 ;PMID: 31117231Full text available |
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Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinomaFrontiers in oncology, 2023-03, Vol.13, p.1140730-1140730 [Peer Reviewed Journal]Copyright © 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci. ;Copyright © 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2023.1140730 ;PMID: 36998446Full text available |
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Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver DiseaseJournal of the American Heart Association, 2023-12, Vol.12 (23), p.e031241-e031241 [Peer Reviewed Journal]2023 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. ;ISSN: 2047-9980 ;EISSN: 2047-9980 ;DOI: 10.1161/JAHA.123.031241 ;PMID: 37996988Full text available |
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Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver DiseaseFrontiers in pharmacology, 2022-04, Vol.13, p.858137-858137 [Peer Reviewed Journal]Copyright © 2022 Fiorucci, Rapacciuolo, Fiorillo, Roselli, Marchianò, Di Giorgio, Bordoni, Bellini, Cassiano, Conflitti, Catalanotti, Limongelli, Sepe, Biagioli and Zampella. 2022 Fiorucci, Rapacciuolo, Fiorillo, Roselli, Marchianò, Di Giorgio, Bordoni, Bellini, Cassiano, Conflitti, Catalanotti, Limongelli, Sepe, Biagioli and Zampella ;ISSN: 1663-9812 ;EISSN: 1663-9812 ;DOI: 10.3389/fphar.2022.858137 ;PMID: 35559268Full text available |
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The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancerCellular oncology (Dordrecht), 2024-04, Vol.47 (2), p.695-710The Author(s) 2023 ;ISSN: 2211-3428 ;EISSN: 2211-3436 ;DOI: 10.1007/s13402-023-00893-8Digital Resources/Online E-Resources |
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GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against ColitisACS medicinal chemistry letters, 2020-05, Vol.11 (5), p.818-824 [Peer Reviewed Journal]Copyright © 2020 American Chemical Society. ;Copyright © 2020 American Chemical Society 2020 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/acsmedchemlett.9b00636 ;PMID: 32435390Full text available |
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Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”ACS omega, 2023-11, Vol.8 (47), p.45163-45163 [Peer Reviewed Journal]2023 The Authors. Published by American Chemical Society 2023 The Authors ;ISSN: 2470-1343 ;EISSN: 2470-1343 ;DOI: 10.1021/acsomega.3c08464Full text available |
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Material Type: Article
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GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in InflammationCells (Basel, Switzerland), 2022-04, Vol.11 (7), p.1187 [Peer Reviewed Journal]2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells11071187 ;PMID: 35406751Full text available |
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Material Type: Article
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Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic AdenocarcinomaCells (Basel, Switzerland), 2022-11, Vol.11 (21), p.3482 [Peer Reviewed Journal]COPYRIGHT 2022 MDPI AG ;2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells11213482 ;PMID: 36359879Full text available |
16 |
Material Type: Article
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The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver ToxicityThe Journal of immunology (1950), 2020-05, Vol.204 (9), p.2535-2551 [Peer Reviewed Journal]Copyright © 2020 by The American Association of Immunologists, Inc. ;ISSN: 0022-1767 ;EISSN: 1550-6606 ;DOI: 10.4049/jimmunol.1901427 ;PMID: 32213564Full text available |
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Material Type: Article
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Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signalingThe FASEB journal, 2022-01, Vol.36 (1), p.e22060-n/a [Peer Reviewed Journal]2021 The Authors. published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology. ;2021 The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology. ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.202101397R ;PMID: 34862975Full text available |
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Material Type: Article
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GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated HepatitisCellular and molecular gastroenterology and hepatology, 2019-01, Vol.8 (3), p.447-473 [Peer Reviewed Journal]The Authors ;2019 The Authors ;Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved. ;2019 The Authors 2019 ;ISSN: 2352-345X ;EISSN: 2352-345X ;DOI: 10.1016/j.jcmgh.2019.06.003 ;PMID: 31226434Full text available |
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Material Type: Article
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Discovery of a Potent and Orally Active Dual GPBAR1/CysLT 1 R Modulator for the Treatment of Metabolic Fatty Liver DiseaseFrontiers in pharmacology, 2022, Vol.13, p.858137 [Peer Reviewed Journal]Copyright © 2022 Fiorucci, Rapacciuolo, Fiorillo, Roselli, Marchianò, Di Giorgio, Bordoni, Bellini, Cassiano, Conflitti, Catalanotti, Limongelli, Sepe, Biagioli and Zampella. ;ISSN: 1663-9812 ;EISSN: 1663-9812 ;PMID: 35559268Full text available |
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Material Type: Article
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Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated DisordersACS omega, 2023-02, Vol.8 (6), p.5983-5994 [Peer Reviewed Journal]2023 The Authors. Published by American Chemical Society ;2023 The Authors. Published by American Chemical Society. ;2023 The Authors. Published by American Chemical Society 2023 The Authors ;ISSN: 2470-1343 ;EISSN: 2470-1343 ;DOI: 10.1021/acsomega.2c07907 ;PMID: 36816679Full text available |