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1
Targeting epigenetic modifications in cancer therapy: erasing the roadmap to cancer
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Article
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Targeting epigenetic modifications in cancer therapy: erasing the roadmap to cancer

Nature medicine, 2019-03, Vol.25 (3), p.403-418 [Peer Reviewed Journal]

COPYRIGHT 2019 Nature Publishing Group ;COPYRIGHT 2019 Nature Publishing Group ;2019© Springer Nature America, Inc. 2019 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/s41591-019-0376-8 ;PMID: 30842676

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2
Genomic landscape of lung adenocarcinoma in East Asians
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Article
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Genomic landscape of lung adenocarcinoma in East Asians

Nature genetics, 2020-02, Vol.52 (2), p.177-186 [Peer Reviewed Journal]

COPYRIGHT 2020 Nature Publishing Group ;COPYRIGHT 2020 Nature Publishing Group ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/s41588-019-0569-6 ;PMID: 32015526

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3
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
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Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.2989-2994 [Peer Reviewed Journal]

copyright © 1993-2008 National Acadamy of Sciences of the United States of America ;Copyright National Academy of Sciences Feb 21, 2012 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1116418109 ;PMID: 22323599

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4
Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer
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Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer

Oncotarget, 2013-12, Vol.4 (12), p.2419-2429

Copyright: © 2013 Wyce et al. 2013 ;ISSN: 1949-2553 ;EISSN: 1949-2553 ;DOI: 10.18632/oncotarget.1572 ;PMID: 24293458

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5
Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2
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Article
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Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2

ACS medicinal chemistry letters, 2012-12, Vol.3 (12), p.1091-1096 [Peer Reviewed Journal]

Copyright © 2012 American Chemical Society ;Copyright © 2012 American Chemical Society 2012 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/ml3003346 ;PMID: 24900432

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6
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML
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Article
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Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML

Cancer discovery, 2019-07, Vol.9 (7), p.872-889

2019 American Association for Cancer Research. ;ISSN: 2159-8274 ;EISSN: 2159-8290 ;DOI: 10.1158/2159-8290.cd-19-0106 ;PMID: 31076479

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7
Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice
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Article
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Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice

Molecular and Cellular Biology, 2004-11, Vol.24 (22), p.9848-9862 [Peer Reviewed Journal]

Copyright © 2004, American Society for Microbiology 2004 ;ISSN: 0270-7306 ;ISSN: 1098-5549 ;EISSN: 1098-5549 ;DOI: 10.1128/MCB.24.22.9848-9862.2004 ;PMID: 15509788

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8
A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation
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Article
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A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation

Molecular cancer therapeutics, 2014-12, Vol.13 (12), p.3062-3073 [Peer Reviewed Journal]

2014 American Association for Cancer Research. ;ISSN: 1535-7163 ;EISSN: 1538-8514 ;DOI: 10.1158/1535-7163.mct-13-0876 ;PMID: 25253781

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9
Long Residence Time Inhibition of EZH2 in Activated Polycomb Repressive Complex 2
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Article
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Long Residence Time Inhibition of EZH2 in Activated Polycomb Repressive Complex 2

ACS chemical biology, 2014-03, Vol.9 (3), p.622-629 [Peer Reviewed Journal]

Copyright © 2013 American Chemical Society ;ISSN: 1554-8929 ;EISSN: 1554-8937 ;DOI: 10.1021/cb4008748 ;PMID: 24304166

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10
The Serine Protease Omi/HtrA2 Regulates Apoptosis by Binding XIAP through a Reaper-like Motif
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Article
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The Serine Protease Omi/HtrA2 Regulates Apoptosis by Binding XIAP through a Reaper-like Motif

The Journal of biological chemistry, 2002-01, Vol.277 (1), p.439-444 [Peer Reviewed Journal]

2002 © 2002 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M109784200 ;PMID: 11602612

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11
DYRK3 Dual-specificity Kinase Attenuates Erythropoiesis during Anemia
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Article
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DYRK3 Dual-specificity Kinase Attenuates Erythropoiesis during Anemia

The Journal of biological chemistry, 2008-12, Vol.283 (52), p.36665-36675 [Peer Reviewed Journal]

2008 © 2008 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;Copyright © 2008, The American Society for Biochemistry and Molecular Biology, Inc. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M807844200 ;PMID: 18854306

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12
mDYRK3 kinase is expressed selectively in late erythroid progenitor cells and attenuates colony-forming unit-erythroid development
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Article
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mDYRK3 kinase is expressed selectively in late erythroid progenitor cells and attenuates colony-forming unit-erythroid development

Blood, 2001-02, Vol.97 (4), p.901-910 [Peer Reviewed Journal]

2001 INIST-CNRS ;ISSN: 0006-4971 ;EISSN: 1528-0020 ;DOI: 10.1182/blood.v97.4.901 ;PMID: 11159515

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13
Cloning and characterization of a member of the MST subfamily of Ste20-like kinases
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Article
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Cloning and characterization of a member of the MST subfamily of Ste20-like kinases

Gene, 1995-12, Vol.167 (1), p.303-306 [Peer Reviewed Journal]

1995 ;ISSN: 0378-1119 ;EISSN: 1879-0038 ;DOI: 10.1016/0378-1119(95)00653-2 ;PMID: 8566796

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14
Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response
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Article
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Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

European journal of biochemistry, 2000-09, Vol.267 (18), p.5699-5710 [Peer Reviewed Journal]

ISSN: 0014-2956 ;EISSN: 1432-1033 ;DOI: 10.1046/j.1432-1327.2000.01589.x ;PMID: 10971580

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15
Saccharomyces cerevisiae Yak1p protein kinase autophosphorylates on tyrosine residues and phosphorylates myelin basic protein on a C-terminal serine residue
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Saccharomyces cerevisiae Yak1p protein kinase autophosphorylates on tyrosine residues and phosphorylates myelin basic protein on a C-terminal serine residue

Biochemical journal, 2000-06, Vol.348 Pt 2 (2), p.263-272 [Peer Reviewed Journal]

ISSN: 0264-6021 ;EISSN: 1470-8728 ;DOI: 10.1042/0264-6021:3480263 ;PMID: 10816418

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16
REDK, a novel human regulatory erythroid kinase
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REDK, a novel human regulatory erythroid kinase

Blood, 2000-05, Vol.95 (9), p.2838-2846 [Peer Reviewed Journal]

2000 American Society of Hematology ;2000 INIST-CNRS ;ISSN: 0006-4971 ;EISSN: 1528-0020 ;DOI: 10.1182/blood.V95.9.2838.009k29_2838_2846 ;PMID: 10779429

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17
Structure-function relationships of the yeast cyclin-dependent kinase Pho85
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Article
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Structure-function relationships of the yeast cyclin-dependent kinase Pho85

Molecular and Cellular Biology, 1995-10, Vol.15 (10), p.5482-5491 [Peer Reviewed Journal]

Copyright © 1995, American Society for Microbiology 1995 ;ISSN: 0270-7306 ;ISSN: 1098-5549 ;EISSN: 1098-5549 ;DOI: 10.1128/MCB.15.10.5482 ;PMID: 7565699

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18
Identification of a Mouse p21Cdc42/Rac Activated Kinase
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Article
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Identification of a Mouse p21Cdc42/Rac Activated Kinase

The Journal of biological chemistry, 1995-09, Vol.270 (39), p.22731-22737 [Peer Reviewed Journal]

ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.270.39.22731 ;PMID: 7559398

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