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1 |
Material Type: Article
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Precisely Ordered Phosphorylation Reactions in the p38 Mitogen-activated Protein (MAP) Kinase CascadeThe Journal of biological chemistry, 2013-08, Vol.288 (32), p.23322-23330 [Peer Reviewed Journal]2013 © 2013 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2013 by The American Society for Biochemistry and Molecular Biology, Inc. 2013 ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M113.462101 ;PMID: 23744074Full text available |
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Material Type: Article
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The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cellsThe Journal of biological chemistry, 2020-06, Vol.295 (25), p.8470-8479 [Peer Reviewed Journal]2020 ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.RA119.012365 ;PMID: 32358059Full text available |
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3 |
Material Type: Article
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Structure, Function and Regulation of the Hsp90 MachineryBiomedical Journal, 2013-05, Vol.36 (3), p.106-117 [Peer Reviewed Journal]COPYRIGHT 2013 Medknow Publications and Media Pvt. Ltd. ;Copyright Medknow Publications & Media Pvt Ltd May-Jun 2013 ;ISSN: 2319-4170 ;EISSN: 2320-2890 ;DOI: 10.4103/2319-4170.113230 ;PMID: 23806880Full text available |
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Material Type: Article
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The Global Phosphorylation Landscape of SARS-CoV-2 InfectionCell, 2020-08, Vol.182 (3), p.685-712.e19 [Peer Reviewed Journal]2020 Elsevier Inc. ;Copyright © 2020 Elsevier Inc. All rights reserved. ;2020. Not withstanding the ProQuest Terms and Conditions, you may use this content in accordance with the associated terms available at https://www.elsevier.com/legal/elsevier-website-terms-and-conditions ;Attribution - NonCommercial ;2020 Elsevier Inc. 2020 Elsevier Inc. ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2020.06.034 ;PMID: 32645325Digital Resources/Online E-Resources |
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5 |
Material Type: Article
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Structural Insights Support Targeting ASK1 Kinase for Therapeutic InterventionsInternational journal of molecular sciences, 2021-12, Vol.22 (24), p.13395 [Peer Reviewed Journal]2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 by the authors. 2021 ;ISSN: 1422-0067 ;ISSN: 1661-6596 ;EISSN: 1422-0067 ;DOI: 10.3390/ijms222413395 ;PMID: 34948191Full text available |
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6 |
Material Type: Article
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RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction-pointNature communications, 2019-04, Vol.10 (1), p.1897-17, Article 1897 [Peer Reviewed Journal]The Author(s) 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-019-09810-w ;PMID: 31015486Full text available |
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7 |
Material Type: Article
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PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomasNature (London), 2017-10, Vol.550 (7674), p.133-136 [Peer Reviewed Journal]COPYRIGHT 2017 Nature Publishing Group ;COPYRIGHT 2017 Nature Publishing Group ;Copyright Nature Publishing Group Oct 5, 2017 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature24040 ;PMID: 28953887Full text available |
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Material Type: Article
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Structural basis for the action of the drug trametinib at KSR-bound MEKNature (London), 2020-12, Vol.588 (7838), p.509-514 [Peer Reviewed Journal]Copyright Nature Publishing Group Dec 17, 2020 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-020-2760-4 ;PMID: 32927473Full text available |
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Material Type: Article
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MEKK1/MEKK4 are responsible for TRAIL-induced JNK/p38 phosphorylationOncology reports, 2011-02, Vol.25 (2), p.537-5442015 INIST-CNRS ;ISSN: 1021-335X ;EISSN: 1791-2431 ;DOI: 10.3892/or.2010.1079 ;PMID: 21152872Full text available |
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10 |
Material Type: Article
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Phosphorylation of microtubule‐associated protein tau by isoforms of c‐Jun N‐terminal kinase (JNK)Journal of neurochemistry, 2004-07, Vol.90 (2), p.352-358 [Peer Reviewed Journal]2005 INIST-CNRS ;ISSN: 0022-3042 ;EISSN: 1471-4159 ;DOI: 10.1111/j.1471-4159.2004.02479.x ;PMID: 15228592 ;CODEN: JONRA9Full text available |
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Material Type: Article
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Integrative Genomic and Proteomic Analyses Identify Targets for Lkb1-Deficient Metastatic Lung TumorsCancer cell, 2010-06, Vol.17 (6), p.547-559 [Peer Reviewed Journal]2010 Elsevier Inc. ;Copyright 2010 Elsevier Inc. All rights reserved. ;2010 Elsevier Inc. All rights reserved. 2010 ;ISSN: 1535-6108 ;EISSN: 1878-3686 ;DOI: 10.1016/j.ccr.2010.04.026 ;PMID: 20541700Full text available |
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Material Type: Article
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Dysregulation of Wnt/β‐catenin signaling by protein kinases in hepatocellular carcinoma and its therapeutic applicationCancer science, 2021-05, Vol.112 (5), p.1695-1706 [Peer Reviewed Journal]2021 The Authors. published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association. ;2021 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association. ;2021. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1347-9032 ;EISSN: 1349-7006 ;DOI: 10.1111/cas.14861 ;PMID: 33605517Full text available |
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13 |
Material Type: Article
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Droplet-based screening of phosphate transfer catalysis reveals how epistasis shapes MAP kinase interactions with substratesNature communications, 2022-02, Vol.13 (1), p.844-844, Article 844 [Peer Reviewed Journal]2022. The Author(s). ;The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2022 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-022-28396-4 ;PMID: 35149678Full text available |
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Material Type: Article
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The redox‐active site of thioredoxin is directly involved in apoptosis signal‐regulating kinase 1 binding that is modulated by oxidative stressThe FEBS journal, 2020-04, Vol.287 (8), p.1626-1644 [Peer Reviewed Journal]2019 Federation of European Biochemical Societies ;2019 Federation of European Biochemical Societies. ;Copyright © 2020 Federation of European Biochemical Societies ;ISSN: 1742-464X ;EISSN: 1742-4658 ;DOI: 10.1111/febs.15101 ;PMID: 31623019Full text available |
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Material Type: Article
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The Aspergillus nidulans MAPK module AnSte11-Ste50-Ste7-Fus3 controls development and secondary metabolismPLoS genetics, 2012-07, Vol.8 (7), p.e1002816-e1002816 [Peer Reviewed Journal]COPYRIGHT 2012 Public Library of Science ;COPYRIGHT 2012 Public Library of Science ;2012 Bayram et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Bayram Ö, Bayram ÖS, Ahmed YL, Maruyama J-i, Valerius O, et al. (2012) The Aspergillus nidulans MAPK Module AnSte11-Ste50-Ste7-Fus3 Controls Development and Secondary Metabolism. PLoS Genet 8(7): e1002816. doi:10.1371/journal.pgen.1002816 ;Bayram et al. 2012 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1002816 ;PMID: 22829779Full text available |
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Material Type: Article
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Kir2.1 Interaction with Stk38 Promotes Invasion and Metastasis of Human Gastric Cancer by Enhancing MEKK2-MEK1/2-ERK1/2 SignalingCancer research (Chicago, Ill.), 2018-06, Vol.78 (11), p.3041-3053 [Peer Reviewed Journal]2018 American Association for Cancer Research. ;Copyright American Association for Cancer Research, Inc. Jun 1, 2018 ;ISSN: 0008-5472 ;EISSN: 1538-7445 ;DOI: 10.1158/0008-5472.CAN-17-3776 ;PMID: 29549164Full text available |
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Material Type: Article
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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesisCancer research (Chicago, Ill.), 2004-10, Vol.64 (19), p.7099-7109 [Peer Reviewed Journal]2004 INIST-CNRS ;ISSN: 0008-5472 ;EISSN: 1538-7445 ;DOI: 10.1158/0008-5472.CAN-04-1443 ;PMID: 15466206 ;CODEN: CNREA8Full text available |
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Material Type: Article
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Inhibition of p70 S6 kinase activity by A77 1726 induces autophagy and enhances the degradation of superoxide dismutase 1 (SOD1) protein aggregatesCell death & disease, 2018-03, Vol.9 (3), p.407-16, Article 407 [Peer Reviewed Journal]2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2018 ;ISSN: 2041-4889 ;EISSN: 2041-4889 ;DOI: 10.1038/s41419-018-0441-0 ;PMID: 29540819Full text available |
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19 |
Material Type: Article
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TGFβ-activated Kinase 1 (TAK1) Inhibition by 5Z-7-Oxozeaenol Attenuates Early Brain Injury after Experimental Subarachnoid HemorrhageThe Journal of biological chemistry, 2015-08, Vol.290 (32), p.19900-19909 [Peer Reviewed Journal]2015 © 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2015 by The American Society for Biochemistry and Molecular Biology, Inc. ;2015 by The American Society for Biochemistry and Molecular Biology, Inc. 2015 ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M115.636795 ;PMID: 26100626Full text available |
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Material Type: Article
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MEK drives BRAF activation through allosteric control of KSR proteinsNature (London), 2018-02, Vol.554 (7693), p.549-553 [Peer Reviewed Journal]COPYRIGHT 2018 Nature Publishing Group ;COPYRIGHT 2018 Nature Publishing Group ;Copyright Nature Publishing Group Feb 22, 2018 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature25478 ;PMID: 29433126Full text available |