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1
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis
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The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

The Journal of immunology (1950), 2017-07, Vol.199 (2), p.718-733 [Peer Reviewed Journal]

Copyright © 2017 by The American Association of Immunologists, Inc. ;Copyright American Association of Immunologists Jul 15, 2017 ;ISSN: 0022-1767 ;EISSN: 1550-6606 ;DOI: 10.4049/jimmunol.1700183 ;PMID: 28607110

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2
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
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Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

Frontiers in chemistry, 2020-10, Vol.8, p.572885-572885 [Peer Reviewed Journal]

Copyright © 2020 Carino, Moraca, Fiorillo, Marchianò, Sepe, Biagioli, Finamore, Bozza, Francisci, Distrutti, Catalanotti, Zampella and Fiorucci. ;Copyright © 2020 Carino, Moraca, Fiorillo, Marchianò, Sepe, Biagioli, Finamore, Bozza, Francisci, Distrutti, Catalanotti, Zampella and Fiorucci. 2020 Carino, Moraca, Fiorillo, Marchianò, Sepe, Biagioli, Finamore, Bozza, Francisci, Distrutti, Catalanotti, Zampella and Fiorucci ;ISSN: 2296-2646 ;EISSN: 2296-2646 ;DOI: 10.3389/fchem.2020.572885 ;PMID: 33195060

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3
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy
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The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy

The FASEB journal, 2021-01, Vol.35 (1), p.e21271-n/a [Peer Reviewed Journal]

2020 Federation of American Societies for Experimental Biology ;2020 Federation of American Societies for Experimental Biology. ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.202001386R ;PMID: 33368684

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4
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
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Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH

Scientific reports, 2023-01, Vol.13 (1), p.1602-1602, Article 1602 [Peer Reviewed Journal]

2023. The Author(s). ;The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2023 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-023-28647-4 ;PMID: 36709356

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5
Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists
Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists
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Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists

ACS medicinal chemistry letters, 2019-04, Vol.10 (4), p.504-510 [Peer Reviewed Journal]

Copyright © 2019 American Chemical Society 2019 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/acsmedchemlett.8b00534 ;PMID: 30996787

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6
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists
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Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists

Molecules (Basel, Switzerland), 2023-03, Vol.28 (6), p.2840 [Peer Reviewed Journal]

2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2023 by the authors. 2023 ;ISSN: 1420-3049 ;EISSN: 1420-3049 ;DOI: 10.3390/molecules28062840 ;PMID: 36985811

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7
Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes
Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes
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Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes

Stem cell reports, 2021-10, Vol.16 (10), p.2473-2487 [Peer Reviewed Journal]

2021 The Authors ;Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved. ;2021 The Authors 2021 ;ISSN: 2213-6711 ;EISSN: 2213-6711 ;DOI: 10.1016/j.stemcr.2021.08.005 ;PMID: 34506727

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8
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1
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Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1

Journal of medicinal chemistry, 2021-11, Vol.64 (22), p.16512 [Peer Reviewed Journal]

EISSN: 1520-4804 ;DOI: 10.1021/acs.jmedchem.1c01078 ;PMID: 34767347

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9
Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
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Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis

Frontiers in oncology, 2022-06, Vol.12, p.939969-939969 [Peer Reviewed Journal]

Copyright © 2022 Di Giorgio, Marchianò, Marino, Biagioli, Roselli, Bordoni, Bellini, Urbani, Zampella, Distrutti, Donini, Graziosi and Fiorucci 2022 Di Giorgio, Marchianò, Marino, Biagioli, Roselli, Bordoni, Bellini, Urbani, Zampella, Distrutti, Donini, Graziosi and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2022.939969 ;PMID: 35847866

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10
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
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Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

Nutrients, 2019-05, Vol.11 (5), p.1132 [Peer Reviewed Journal]

2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu11051132 ;PMID: 31117231

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11
The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions
The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions
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The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions

Nutrients, 2019-08, Vol.11 (8), p.1820 [Peer Reviewed Journal]

2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu11081820 ;PMID: 31394746

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12
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
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Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma

Frontiers in oncology, 2023-03, Vol.13, p.1140730-1140730 [Peer Reviewed Journal]

Copyright © 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci. ;Copyright © 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2023.1140730 ;PMID: 36998446

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13
Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease
Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease
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Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease

Journal of the American Heart Association, 2023-12, Vol.12 (23), p.e031241-e031241 [Peer Reviewed Journal]

2023 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. ;ISSN: 2047-9980 ;EISSN: 2047-9980 ;DOI: 10.1161/JAHA.123.031241 ;PMID: 37996988

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14
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands
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Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands

Scientific reports, 2016-07, Vol.6 (1), p.29320-29320, Article 29320 [Peer Reviewed Journal]

Copyright Nature Publishing Group Jul 2016 ;Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep29320 ;PMID: 27381677

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15
GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
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GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation

Cells (Basel, Switzerland), 2022-04, Vol.11 (7), p.1187 [Peer Reviewed Journal]

2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells11071187 ;PMID: 35406751

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16
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
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Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma

Cells (Basel, Switzerland), 2022-11, Vol.11 (21), p.3482 [Peer Reviewed Journal]

COPYRIGHT 2022 MDPI AG ;2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells11213482 ;PMID: 36359879

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17
Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases
Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases
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Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases

Frontiers in pharmacology, 2017-03, Vol.8, p.162-162 [Peer Reviewed Journal]

COPYRIGHT 2017 Frontiers Research Foundation ;Copyright © 2017 Festa, De Marino, Carino, Sepe, Marchianò, Cipriani, Di Leva, Limongelli, Monti, Capolupo, Distrutti, Fiorucci and Zampella. 2017 Festa, De Marino, Carino, Sepe, Marchianò, Cipriani, Di Leva, Limongelli, Monti, Capolupo, Distrutti, Fiorucci and Zampella ;ISSN: 1663-9812 ;EISSN: 1663-9812 ;DOI: 10.3389/fphar.2017.00162 ;PMID: 28424617

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18
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease
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Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease

Frontiers in pharmacology, 2022-04, Vol.13, p.858137-858137 [Peer Reviewed Journal]

Copyright © 2022 Fiorucci, Rapacciuolo, Fiorillo, Roselli, Marchianò, Di Giorgio, Bordoni, Bellini, Cassiano, Conflitti, Catalanotti, Limongelli, Sepe, Biagioli and Zampella. 2022 Fiorucci, Rapacciuolo, Fiorillo, Roselli, Marchianò, Di Giorgio, Bordoni, Bellini, Cassiano, Conflitti, Catalanotti, Limongelli, Sepe, Biagioli and Zampella ;ISSN: 1663-9812 ;EISSN: 1663-9812 ;DOI: 10.3389/fphar.2022.858137 ;PMID: 35559268

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19
Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine
Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine
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Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine

Nature reviews cardiology, 2020-06, Vol.17 (6), p.341-359 [Peer Reviewed Journal]

COPYRIGHT 2020 Nature Publishing Group ;This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2020. ;ISSN: 1759-5002 ;EISSN: 1759-5010 ;DOI: 10.1038/s41569-019-0331-x ;PMID: 32015528

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20
Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”
Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”
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Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”

ACS omega, 2023-11, Vol.8 (47), p.45163-45163 [Peer Reviewed Journal]

2023 The Authors. Published by American Chemical Society 2023 The Authors ;ISSN: 2470-1343 ;EISSN: 2470-1343 ;DOI: 10.1021/acsomega.3c08464

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