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1
Morphine‐induced respiratory depression is independent of β‐arrestin2 signalling
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Morphine‐induced respiratory depression is independent of β‐arrestin2 signalling

British journal of pharmacology, 2020-07, Vol.177 (13), p.2923-2931 [Peer Reviewed Journal]

2020 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society ;2020 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society. ;2020. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 0007-1188 ;EISSN: 1476-5381 ;DOI: 10.1111/bph.15004 ;PMID: 32052419

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2
Agonist-Specific Regulation of G Protein-Coupled Receptors after Chronic Opioid Treatment
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Agonist-Specific Regulation of G Protein-Coupled Receptors after Chronic Opioid Treatment

Molecular pharmacology, 2022-05, Vol.101 (5), p.300-308 [Peer Reviewed Journal]

Copyright © 2022 by The American Society for Pharmacology and Experimental Therapeutics. ;Copyright © 2022 by The American Society for Pharmacology and Experimental Therapeutics 2022 ;ISSN: 0026-895X ;EISSN: 1521-0111 ;DOI: 10.1124/molpharm.121.000453 ;PMID: 35193934

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3
Molecular recognition of morphine and fentanyl by the human μ-opioid receptor
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Molecular recognition of morphine and fentanyl by the human μ-opioid receptor

Cell, 2022-11, Vol.185 (23), p.4361-4375.e19 [Peer Reviewed Journal]

2022 Elsevier Inc. ;Copyright © 2022 Elsevier Inc. All rights reserved. ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2022.09.041 ;PMID: 36368306

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4
Loss of μ opioid receptor signaling in nociceptors, but not microglia, abrogates morphine tolerance without disrupting analgesia
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Loss of μ opioid receptor signaling in nociceptors, but not microglia, abrogates morphine tolerance without disrupting analgesia

Nature medicine, 2017-02, Vol.23 (2), p.164-173 [Peer Reviewed Journal]

ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.4262 ;PMID: 28092666

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5
Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation
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Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation

Proceedings of the National Academy of Sciences - PNAS, 2016-06, Vol.113 (24), p.E3441-E3450 [Peer Reviewed Journal]

Volumes 1–89 and 106–113, copyright as a collective work only; author(s) retains copyright to individual articles ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1602070113 ;PMID: 27247388

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6
A thalamic input to the nucleus accumbens mediates opiate dependence
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A thalamic input to the nucleus accumbens mediates opiate dependence

Nature (London), 2016-02, Vol.530 (7589), p.219-222 [Peer Reviewed Journal]

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Feb 11, 2016 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/nature16954 ;PMID: 26840481 ;CODEN: NATUAS

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7
Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses
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Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses

Nature neuroscience, 2016-07, Vol.19 (7), p.915-925 [Peer Reviewed Journal]

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Jul 2016 ;ISSN: 1097-6256 ;EISSN: 1546-1726 ;DOI: 10.1038/nn.4313 ;PMID: 27239940 ;CODEN: NANEFN

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8
Opioid Use in Murine Model Results in Severe Gastric Pathology that May Be Attenuated by Proton Pump Inhibition
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Opioid Use in Murine Model Results in Severe Gastric Pathology that May Be Attenuated by Proton Pump Inhibition

The American journal of pathology, 2022-08, Vol.192 (8), p.1136-1150 [Peer Reviewed Journal]

2022 American Society for Investigative Pathology ;Copyright © 2022 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved. ;2022 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved. 2022 American Society for Investigative Pathology ;ISSN: 0002-9440 ;EISSN: 1525-2191 ;DOI: 10.1016/j.ajpath.2022.04.005 ;PMID: 35605643

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9
Morphine delays and attenuates ticagrelor exposure and action in patients with myocardial infarction: the randomized, double-blind, placebo-controlled IMPRESSION trial
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Morphine delays and attenuates ticagrelor exposure and action in patients with myocardial infarction: the randomized, double-blind, placebo-controlled IMPRESSION trial

European heart journal, 2016-01, Vol.37 (3), p.245-252 [Peer Reviewed Journal]

The Author 2015. Published by Oxford University Press on behalf of the European Society of Cardiology. ;The Author 2015. Published by Oxford University Press on behalf of the European Society of Cardiology 2015 ;ISSN: 0195-668X ;EISSN: 1522-9645 ;DOI: 10.1093/eurheartj/ehv547 ;PMID: 26491112

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10
A Neural Circuit for the Suppression of Pain by a Competing Need State
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A Neural Circuit for the Suppression of Pain by a Competing Need State

Cell, 2018-03, Vol.173 (1), p.140-152.e15 [Peer Reviewed Journal]

2018 Elsevier Inc. ;Copyright © 2018 Elsevier Inc. All rights reserved. ;ISSN: 0092-8674 ;EISSN: 1097-4172 ;DOI: 10.1016/j.cell.2018.02.057 ;PMID: 29570993

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11
Morphine tolerance is attenuated in germfree mice and reversed by probiotics, implicating the role of gut microbiome
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Morphine tolerance is attenuated in germfree mice and reversed by probiotics, implicating the role of gut microbiome

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (27), p.13523-13532 [Peer Reviewed Journal]

Copyright National Academy of Sciences Jul 2, 2019 ;2019 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1901182116 ;PMID: 31209039

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12
Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors
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Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors

Nature chemical biology, 2020-09, Vol.16 (9), p.946-954 [Peer Reviewed Journal]

The Author(s), under exclusive licence to Springer Nature America, Inc. 2020. ;ISSN: 1552-4450 ;EISSN: 1552-4469 ;DOI: 10.1038/s41589-020-0566-1 ;PMID: 32541966

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13
Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice
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Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice

Neuropsychopharmacology (New York, N.Y.), 2021-12, Vol.46 (13), p.2241-2249 [Peer Reviewed Journal]

2021. The Author(s). ;The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2021 ;ISSN: 0893-133X ;EISSN: 1740-634X ;DOI: 10.1038/s41386-021-01054-x ;PMID: 34257415

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14
Opioid-induced gut microbial disruption and bile dysregulation leads to gut barrier compromise and sustained systemic inflammation
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Opioid-induced gut microbial disruption and bile dysregulation leads to gut barrier compromise and sustained systemic inflammation

Mucosal immunology, 2016-11, Vol.9 (6), p.1418-1428 [Peer Reviewed Journal]

Copyright Nature Publishing Group Nov 2016 ;ISSN: 1933-0219 ;EISSN: 1935-3456 ;DOI: 10.1038/mi.2016.9 ;PMID: 26906406

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15
Coincident Regulation of PLC β Signaling by Gq-Coupled and μ -Opioid Receptors Opposes Opioid-Mediated Antinociception
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Coincident Regulation of PLC β Signaling by Gq-Coupled and μ -Opioid Receptors Opposes Opioid-Mediated Antinociception

Molecular pharmacology, 2022-12, Vol.102 (6), p.269-279 [Peer Reviewed Journal]

Copyright © 2022 by The American Society for Pharmacology and Experimental Therapeutics. ;Copyright © 2022 by The American Society for Pharmacology and Experimental Therapeutics 2022 ;ISSN: 0026-895X ;EISSN: 1521-0111 ;DOI: 10.1124/molpharm.122.000541 ;PMID: 36116788

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16
Alterations in microbiome composition and metabolic byproducts drive behavioral and transcriptional responses to morphine
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Alterations in microbiome composition and metabolic byproducts drive behavioral and transcriptional responses to morphine

Neuropsychopharmacology (New York, N.Y.), 2021-11, Vol.46 (12), p.2062-2072 [Peer Reviewed Journal]

2021. The Author(s), under exclusive licence to American College of Neuropsychopharmacology. ;The Author(s), under exclusive licence to American College of Neuropsychopharmacology 2021. ;The Author(s), under exclusive licence to American College of Neuropsychopharmacology 2021 ;ISSN: 0893-133X ;EISSN: 1740-634X ;DOI: 10.1038/s41386-021-01043-0 ;PMID: 34127799

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17
Decreased alertness due to sleep loss increases pain sensitivity in mice
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Article
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Decreased alertness due to sleep loss increases pain sensitivity in mice

Nature medicine, 2017-06, Vol.23 (6), p.768-774 [Peer Reviewed Journal]

COPYRIGHT 2017 Nature Publishing Group ;COPYRIGHT 2017 Nature Publishing Group ;Copyright Nature Publishing Group Jun 2017 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.4329 ;PMID: 28481358

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18
Morphine coordinates SST and PV interneurons in the prelimbic cortex to disinhibit pyramidal neurons and enhance reward
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Morphine coordinates SST and PV interneurons in the prelimbic cortex to disinhibit pyramidal neurons and enhance reward

Molecular psychiatry, 2021-04, Vol.26 (4), p.1178-1193 [Peer Reviewed Journal]

COPYRIGHT 2021 Nature Publishing Group ;The Author(s) 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 1359-4184 ;EISSN: 1476-5578 ;DOI: 10.1038/s41380-019-0480-7 ;PMID: 31413370

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19
Quantitative assessment of brain glucose metabolic rates using in vivo deuterium magnetic resonance spectroscopy
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Article
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Quantitative assessment of brain glucose metabolic rates using in vivo deuterium magnetic resonance spectroscopy

Journal of cerebral blood flow and metabolism, 2017-11, Vol.37 (11), p.3518-3530 [Peer Reviewed Journal]

The Author(s) 2017 ;The Author(s) 2017 2017 International Society for Cerebral Blood Flow and Metabolism ;ISSN: 0271-678X ;EISSN: 1559-7016 ;DOI: 10.1177/0271678X17706444 ;PMID: 28503999

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20
Benefit and Risk Evaluation of Biased μ-Receptor Agonist Oliceridine versus Morphine
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Benefit and Risk Evaluation of Biased μ-Receptor Agonist Oliceridine versus Morphine

Anesthesiology (Philadelphia), 2020-09, Vol.133 (3), p.559-568 [Peer Reviewed Journal]

Copyright © by 2020, the American Society of Anesthesiologists, Inc. Wolters Kluwer Health, Inc. All Rights Reserved. ;ISSN: 0003-3022 ;EISSN: 1528-1175 ;DOI: 10.1097/ALN.0000000000003441 ;PMID: 32788558

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