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Material Type: Article
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Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug designBiochemical journal, 2010-04, Vol.427 (1), p.19-28 [Peer Reviewed Journal]Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 0264-6021 ;EISSN: 1470-8728 ;DOI: 10.1042/BJ20091530Digital Resources/Online E-Resources |
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Structural Characterization of the Aurora Kinase B “DFG-flip” Using MetadynamicsThe AAPS journal, 2019-12, Vol.22 (1), p.14-14, Article 14 [Peer Reviewed Journal]American Association of Pharmaceutical Scientists 2019 ;ISSN: 1550-7416 ;EISSN: 1550-7416 ;DOI: 10.1208/s12248-019-0399-6 ;PMID: 31853739Full text available |
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Type II Kinase Inhibitors: An Opportunity in Cancer for Rational DesignAnti-cancer agents in medicinal chemistry, 2013-06, Vol.13 (5), p.731-747 [Peer Reviewed Journal]ISSN: 1871-5206 ;EISSN: 1875-5992 ;DOI: 10.2174/1871520611313050008 ;PMID: 23094911Full text available |
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The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domainProceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (30), p.14979-14988 [Peer Reviewed Journal]Copyright © 2019 the Author(s). Published by PNAS. ;Copyright National Academy of Sciences Jul 23, 2019 ;Copyright © 2019 the Author(s). Published by PNAS. 2019 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1900289116 ;PMID: 31292254Full text available |
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Design, synthesis and evaluation of a series of potential prodrugs of a Bruton's tyrosine kinase (BTK) inhibitorFrontiers in pharmacology, 2023-03, Vol.14, p.1162216-1162216 [Peer Reviewed Journal]Copyright © 2023 Xiao, Liao, Huang, Wang, Lan, Wang and Li. ;Copyright © 2023 Xiao, Liao, Huang, Wang, Lan, Wang and Li. 2023 Xiao, Liao, Huang, Wang, Lan, Wang and Li ;ISSN: 1663-9812 ;EISSN: 1663-9812 ;DOI: 10.3389/fphar.2023.1162216 ;PMID: 36969836Full text available |
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Aufbau eines FID-Community-WikisInformationspraxis, 2021-11, Vol.7 (2) [Peer Reviewed Journal]EISSN: 2297-3249 ;DOI: 10.11588/ip.2021.2.82306Full text available |
7 |
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Parameters Extraction of Photovoltaic Models Using an Improved Moth-Flame OptimizationEnergies (Basel), 2019-09, Vol.12 (18), p.3527 [Peer Reviewed Journal]2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1996-1073 ;EISSN: 1996-1073 ;DOI: 10.3390/en12183527Full text available |
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Material Type: Article
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Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation statesProceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (51), p.E11894-E11903 [Peer Reviewed Journal]Volumes 1–89 and 106–115, copyright as a collective work only; author(s) retains copyright to individual articles ;Copyright © 2018 the Author(s). Published by PNAS. ;Copyright National Academy of Sciences Dec 18, 2018 ;Copyright © 2018 the Author(s). Published by PNAS. 2018 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1811158115 ;PMID: 30518564Full text available |
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Material Type: Article
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Structure-based Virtual Screening Approaches in Kinase-directed Drug DiscoveryCurrent topics in medicinal chemistry, 2017-08, Vol.17 (20), p.2235-2259 [Peer Reviewed Journal]Copyright Bentham Science Aug 2017 ;ISSN: 1568-0266 ;EISSN: 1873-4294 ;DOI: 10.2174/1568026617666170224121313Full text available |
10 |
Material Type: Article
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Design and development of photoswitchable DFG-Out RET kinase inhibitorsEuropean journal of medicinal chemistry, 2022-04, Vol.234 [Peer Reviewed Journal]ISSN: 1768-3254 ;ISSN: 0223-5234 ;EISSN: 1768-3254 ;DOI: 10.1016/j.ejmech.2022.114226Digital Resources/Online E-Resources |
11 |
Material Type: Article
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Molecular Mechanism of CCAAT-Enhancer Binding Protein Recruitment by the TRIB1 PseudokinaseStructure (London), 2015-11, Vol.23 (11), p.2111-2121 [Peer Reviewed Journal]2015 Elsevier Ltd ;Copyright © 2015 Elsevier Ltd. All rights reserved. ;ISSN: 0969-2126 ;EISSN: 1878-4186 ;DOI: 10.1016/j.str.2015.08.017 ;PMID: 26455797Full text available |
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Citizens’ deliberation on solutions to fight urban household food waste and nexus with growing urban gardens: The case of porto metropolitan area in PortugalCleaner and Responsible Consumption, 2024-06, Vol.13, p.100188, Article 100188 [Peer Reviewed Journal]2024 The Authors ;ISSN: 2666-7843 ;EISSN: 2666-7843 ;DOI: 10.1016/j.clrc.2024.100188Full text available |
13 |
Material Type: Article
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45 years German Society of Biological Psychiatry (DGBP)Journal of Neural Transmission, 2023-09, Vol.130 (9), p.1091-1096 [Peer Reviewed Journal]The Author(s) 2023 ;ISSN: 0300-9564 ;EISSN: 1435-1463 ;DOI: 10.1007/s00702-023-02645-2Digital Resources/Online E-Resources |
14 |
Material Type: Article
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conserved protonation-dependent switch controls drug binding in the Abl kinaseProceedings of the National Academy of Sciences - PNAS, 2009-01, Vol.106 (1), p.139-144 [Peer Reviewed Journal]2008 by The National Academy of Sciences of the USA ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.0811223106 ;PMID: 19109437Full text available |
15 |
Material Type: Article
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Characterization data of reference cement CEM I 42.5 R used for priority program DFG SPP 2005 “Opus Fluidum Futurum – Rheology of reactive, multiscale, multiphase construction materials”Data in brief, 2019-12, Vol.27, p.104699-104699, Article 104699 [Peer Reviewed Journal]2019 The Authors ;2019 The Authors 2019 ;ISSN: 2352-3409 ;EISSN: 2352-3409 ;DOI: 10.1016/j.dib.2019.104699 ;PMID: 31720343Full text available |
16 |
Material Type: Article
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Efficient Generation 1.5THz Pulses Using DASC/GaAs and DASB/GaAs Multilayer Structures via Difference Frequency Generation 1.5 µm Femtosecond Laser PulsesMathematics interdisciplinary research (Online), 2022-09, Vol.7 (3), p.239-248 [Peer Reviewed Journal]EISSN: 2476-4965 ;DOI: 10.22052/mir.2022.242950.1296Full text available |
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Material Type: Article
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Analyses of the oncogenic BRAFD594G variant reveal a kinase-independent function of BRAF in activating MAPK signalingThe Journal of biological chemistry, 2020-02, Vol.295 (8), p.2407-2420 [Peer Reviewed Journal]2020 © 2020 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;2020 Cope et al. 2020 Cope et al. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.RA119.011536 ;PMID: 31929109Full text available |
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Material Type: Article
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Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structuresProtein science, 2011-02, Vol.20 (2), p.428-436 [Peer Reviewed Journal]Copyright © 2010 The Protein Society ;Copyright © 2010 The Protein Society. ;Copyright © 2011 The Protein Society ;ISSN: 0961-8368 ;EISSN: 1469-896X ;DOI: 10.1002/pro.575 ;PMID: 21280133 ;CODEN: PRCIEIFull text available |
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Material Type: Article
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Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out ConformationACS medicinal chemistry letters, 2015-01, Vol.6 (1), p.53-57 [Peer Reviewed Journal]Copyright © 2014 American Chemical Society ;Copyright © 2014 American Chemical Society 2014 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/ml500242y ;PMID: 25589930Full text available |
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Material Type: Article
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Diaryl Urea: A Privileged Structure in Anticancer AgentsCurrent medicinal chemistry, 2016-05, Vol.23 (15), p.1528-1548 [Peer Reviewed Journal]Copyright Bentham Science Publishers Ltd. May 2016 ;ISSN: 0929-8673 ;EISSN: 1875-533X ;DOI: 10.2174/0929867323666160411142532 ;PMID: 27063259Full text available |