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Results 1 - 20 of 9,995  for All Library Resources

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1
Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1
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Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (11), p.E2096-E2105 [Peer Reviewed Journal]

Volumes 1–89 and 106–114, copyright as a collective work only; author(s) retains copyright to individual articles ;Copyright National Academy of Sciences Mar 14, 2017 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1620813114 ;PMID: 28242696

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2
CK1α, CK1δ, and CK1ε are necrosome components which phosphorylate serine 227 of human RIPK3 to activate necroptosis
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CK1α, CK1δ, and CK1ε are necrosome components which phosphorylate serine 227 of human RIPK3 to activate necroptosis

Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (4), p.1962-1970 [Peer Reviewed Journal]

Copyright National Academy of Sciences Jan 28, 2020 ;2020 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1917112117 ;PMID: 31932442

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3
Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2
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Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (32), p.8155-8160 [Peer Reviewed Journal]

Volumes 1–89 and 106–115, copyright as a collective work only; author(s) retains copyright to individual articles ;Copyright © 2018 the Author(s). Published by PNAS. ;Copyright National Academy of Sciences Aug 7, 2018 ;Copyright © 2018 the Author(s). Published by PNAS. 2018 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1806797115 ;PMID: 29987021

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4
Allosteric modulation of a human protein kinase with monobodies
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Allosteric modulation of a human protein kinase with monobodies

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (28), p.13937-13942 [Peer Reviewed Journal]

Copyright National Academy of Sciences Jul 9, 2019 ;2019 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1906024116 ;PMID: 31239342

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5
SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes
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SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes

Proceedings of the National Academy of Sciences - PNAS, 2022-01, Vol.119 (1) [Peer Reviewed Journal]

Copyright © 2021 the Author(s). Published by PNAS. ;Copyright National Academy of Sciences Jan 4, 2022 ;Copyright © 2021 the Author(s). Published by PNAS. 2021 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.2111703119 ;PMID: 34930825

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6
Processive phosphorylation of ERK MAP kinase in mammalian cells
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Processive phosphorylation of ERK MAP kinase in mammalian cells

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (31), p.12675-12680 [Peer Reviewed Journal]

copyright © 1993–2008 by the National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences Aug 2, 2011 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1104030108 ;PMID: 21768338

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7
Correction to Supporting Information for Sammon et al., Two-step release of kinase autoinhibition in discoidin domain receptor 1
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Correction to Supporting Information for Sammon et al., Two-step release of kinase autoinhibition in discoidin domain receptor 1

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (26) [Peer Reviewed Journal]

Copyright National Academy of Sciences Jun 29, 2021 ;2021 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.2108609118 ;PMID: 34155122

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8
TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 with TPL2 mRNA
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TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 with TPL2 mRNA

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (35), p.e2204752119-e2204752119 [Peer Reviewed Journal]

Copyright National Academy of Sciences Aug 30, 2022 ;Copyright © 2022 the Author(s). Published by PNAS. 2022 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.2204752119 ;PMID: 35994673

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9
Activation of NF-κB by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK–IKKα/β–IκBα and MKK3/6–p38 MAP kinase signaling pathways in epithelial cells
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Activation of NF-κB by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK–IKKα/β–IκBα and MKK3/6–p38 MAP kinase signaling pathways in epithelial cells

Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (15), p.8774-8779 [Peer Reviewed Journal]

Copyright © 2001, The National Academy of Sciences 2001 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.151236098 ;PMID: 11438700

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10
SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status
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SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

Proceedings of the National Academy of Sciences - PNAS, 2023-11, Vol.120 (47), p.e2313137120-e2313137120 [Peer Reviewed Journal]

Copyright National Academy of Sciences Nov 21, 2023 ;Copyright © 2023 the Author(s). Published by PNAS. 2023 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.2313137120 ;PMID: 37972068

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11
Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF
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Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (15), p.6067-6072 [Peer Reviewed Journal]

Copyright © 1993-2008 National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences Apr 12, 2011 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1102554108 ;PMID: 21441104

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12
Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade
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Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (38), p.13870-13875 [Peer Reviewed Journal]

copyright © 1993–2008 National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences Sep 23, 2014 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1414358111 ;PMID: 25189770

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13
Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function
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Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (21), p.8149-8154 [Peer Reviewed Journal]

copyright © 1993-2008 National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences May 22, 2012 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1200804109 ;PMID: 22566623

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14
TAK1 inhibition elicits mitochondrial ROS to block intracellular bacterial colonization
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TAK1 inhibition elicits mitochondrial ROS to block intracellular bacterial colonization

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (25), p.1 [Peer Reviewed Journal]

Copyright National Academy of Sciences Jun 22, 2021 ;2021 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.2023647118 ;PMID: 34161265

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15
Defining a new nomenclature for the structures of active and inactive kinases
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Defining a new nomenclature for the structures of active and inactive kinases

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (14), p.6818-6827 [Peer Reviewed Journal]

Copyright © 2019 the Author(s). Published by PNAS. ;Copyright National Academy of Sciences Apr 2, 2019 ;Copyright © 2019 the Author(s). Published by PNAS. 2019 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1814279116 ;PMID: 30867294

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16
MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components
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MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12679-12684 [Peer Reviewed Journal]

Copyright 1993-1999 National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences Oct 26, 1999 ;Copyright © 1999, The National Academy of Sciences 1999 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.96.22.12679 ;PMID: 10535982

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17
JAK mutations in high-risk childhood acute lymphoblastic leukemia
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Article
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JAK mutations in high-risk childhood acute lymphoblastic leukemia

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (23), p.9414-9418 [Peer Reviewed Journal]

Copyright National Academy of Sciences Jun 9, 2009 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.0811761106 ;PMID: 19470474

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18
Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases
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Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (43), p.21539-21544 [Peer Reviewed Journal]

Copyright © 2019 the Author(s). Published by PNAS. ;Copyright National Academy of Sciences Oct 22, 2019 ;Copyright © 2019 the Author(s). Published by PNAS. 2019 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1907566116 ;PMID: 31591208

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19
MEK1 mutations confer resistance to MEK and B-RAF inhibition
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MEK1 mutations confer resistance to MEK and B-RAF inhibition

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (48), p.20411-20416 [Peer Reviewed Journal]

Copyright National Academy of Sciences Dec 1, 2009 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.0905833106 ;PMID: 19915144

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20
IRAK-4: A Novel Member of the IRAK Family with the Properties of an IRAK-Kinase
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IRAK-4: A Novel Member of the IRAK Family with the Properties of an IRAK-Kinase

Proceedings of the National Academy of Sciences - PNAS, 2002-04, Vol.99 (8), p.5567-5572 [Peer Reviewed Journal]

Copyright 1993-2002 National Academy of Sciences of the United States of America ;Copyright National Academy of Sciences Apr 16, 2002 ;Copyright © 2002, The National Academy of Sciences 2002 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.082100399 ;PMID: 11960013

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