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1
Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation
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Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation

ACS medicinal chemistry letters, 2015-01, Vol.6 (1), p.53-57 [Peer Reviewed Journal]

Copyright © 2014 American Chemical Society ;Copyright © 2014 American Chemical Society 2014 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/ml500242y ;PMID: 25589930

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2
Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series
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Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series

ACS medicinal chemistry letters, 2015-06, Vol.6 (6), p.711-715 [Peer Reviewed Journal]

Copyright © 2015 American Chemical Society ;Copyright © 2015 American Chemical Society 2015 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/acsmedchemlett.5b00151 ;PMID: 26101579

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3
Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195
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Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195

ACS medicinal chemistry letters, 2013-02, Vol.4 (2), p.211-215 [Peer Reviewed Journal]

Copyright © 2013 American Chemical Society ;Copyright © 2013 American Chemical Society 2013 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/ml300348c ;PMID: 24900653

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4
A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases
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A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases

ACS medicinal chemistry letters, 2012-04, Vol.3 (4), p.342-346 [Peer Reviewed Journal]

Copyright © 2012 American Chemical Society ;Copyright © 2012 American Chemical Society 2012 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/ml3000403 ;PMID: 24900475

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