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1
Bile Acids Activated Receptors Regulate Innate Immunity
Bile Acids Activated Receptors Regulate Innate Immunity
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Bile Acids Activated Receptors Regulate Innate Immunity

Frontiers in immunology, 2018-08, Vol.9, p.1853-1853 [Peer Reviewed Journal]

Copyright © 2018 Fiorucci, Biagioli, Zampella and Distrutti. 2018 Fiorucci, Biagioli, Zampella and Distrutti ;ISSN: 1664-3224 ;EISSN: 1664-3224 ;DOI: 10.3389/fimmu.2018.01853 ;PMID: 30150987

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2
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis
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The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

The Journal of immunology (1950), 2017-07, Vol.199 (2), p.718-733 [Peer Reviewed Journal]

Copyright © 2017 by The American Association of Immunologists, Inc. ;Copyright American Association of Immunologists Jul 15, 2017 ;ISSN: 0022-1767 ;EISSN: 1550-6606 ;DOI: 10.4049/jimmunol.1700183 ;PMID: 28607110

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3
Theonella : A Treasure Trove of Structurally Unique and Biologically Active Sterols
Theonella : A Treasure Trove of Structurally Unique and Biologically Active Sterols
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Theonella : A Treasure Trove of Structurally Unique and Biologically Active Sterols

Marine drugs, 2023-05, Vol.21 (5), p.291 [Peer Reviewed Journal]

2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2023 by the authors. 2023 ;ISSN: 1660-3397 ;EISSN: 1660-3397 ;DOI: 10.3390/md21050291 ;PMID: 37233485

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4
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
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Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

Frontiers in chemistry, 2020-10, Vol.8, p.572885-572885 [Peer Reviewed Journal]

Copyright © 2020 Carino, Moraca, Fiorillo, Marchianò, Sepe, Biagioli, Finamore, Bozza, Francisci, Distrutti, Catalanotti, Zampella and Fiorucci. ;Copyright © 2020 Carino, Moraca, Fiorillo, Marchianò, Sepe, Biagioli, Finamore, Bozza, Francisci, Distrutti, Catalanotti, Zampella and Fiorucci. 2020 Carino, Moraca, Fiorillo, Marchianò, Sepe, Biagioli, Finamore, Bozza, Francisci, Distrutti, Catalanotti, Zampella and Fiorucci ;ISSN: 2296-2646 ;EISSN: 2296-2646 ;DOI: 10.3389/fchem.2020.572885 ;PMID: 33195060

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5
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy
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The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy

The FASEB journal, 2021-01, Vol.35 (1), p.e21271-n/a [Peer Reviewed Journal]

2020 Federation of American Societies for Experimental Biology ;2020 Federation of American Societies for Experimental Biology. ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.202001386R ;PMID: 33368684

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6
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
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Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH

Scientific reports, 2023-01, Vol.13 (1), p.1602-1602, Article 1602 [Peer Reviewed Journal]

2023. The Author(s). ;The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2023 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-023-28647-4 ;PMID: 36709356

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7
The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation
The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation
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The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation

PloS one, 2013-01, Vol.8 (1), p.e54472 [Peer Reviewed Journal]

COPYRIGHT 2013 Public Library of Science ;COPYRIGHT 2013 Public Library of Science ;2013 Renga et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2013 Renga et al 2013 Renga et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0054472 ;PMID: 23372731

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8
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction
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Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1092 [Peer Reviewed Journal]

2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 1422-0067 ;ISSN: 1661-6596 ;EISSN: 1422-0067 ;DOI: 10.3390/ijms23031092 ;PMID: 35163018

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9
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists
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Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists

Molecules (Basel, Switzerland), 2023-03, Vol.28 (6), p.2840 [Peer Reviewed Journal]

2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2023 by the authors. 2023 ;ISSN: 1420-3049 ;EISSN: 1420-3049 ;DOI: 10.3390/molecules28062840 ;PMID: 36985811

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10
Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling
Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling
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Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling

PloS one, 2015-07, Vol.10 (7), p.e0129866-e0129866 [Peer Reviewed Journal]

2015 Cipriani et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2015 Cipriani et al 2015 Cipriani et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0129866 ;PMID: 26177448

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11
Development of FXR, PXR and CAR Agonists and Antagonists for Treatment of Liver Disorders
Development of FXR, PXR and CAR Agonists and Antagonists for Treatment of Liver Disorders
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Development of FXR, PXR and CAR Agonists and Antagonists for Treatment of Liver Disorders

Current topics in medicinal chemistry, 2012-03, Vol.12 (6), p.605-624 [Peer Reviewed Journal]

ISSN: 1568-0266 ;DOI: 10.2174/156802612799436678

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12
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists
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Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists

Scientific reports, 2016-01, Vol.6 (1), p.19008-19008, Article 19008 [Peer Reviewed Journal]

Copyright Nature Publishing Group Jan 2016 ;Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep19008 ;PMID: 26740187

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13
Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential
Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential
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Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential

Frontiers in oncology, 2021-05, Vol.11, p.663771-663771 [Peer Reviewed Journal]

Copyright © 2021 Carino, Graziosi, Marchianò, Biagioli, Marino, Sepe, Zampella, Distrutti, Donini and Fiorucci. ;Copyright © 2021 Carino, Graziosi, Marchianò, Biagioli, Marino, Sepe, Zampella, Distrutti, Donini and Fiorucci 2021 Carino, Graziosi, Marchianò, Biagioli, Marino, Sepe, Zampella, Distrutti, Donini and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2021.663771 ;PMID: 34012923

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14
Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition
Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition
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Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition

The FASEB journal, 2012-07, Vol.26 (7), p.3021-3031 [Peer Reviewed Journal]

FASEB ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.11-195701 ;PMID: 22447981

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15
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
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Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

Nutrients, 2019-05, Vol.11 (5), p.1132 [Peer Reviewed Journal]

2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 by the authors. 2019 ;ISSN: 2072-6643 ;EISSN: 2072-6643 ;DOI: 10.3390/nu11051132 ;PMID: 31117231

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16
Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism
Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism
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Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism

Scientific reports, 2015-11, Vol.5 (1), p.16605-16605, Article 16605 [Peer Reviewed Journal]

Copyright Nature Publishing Group Nov 2015 ;Copyright © 2015, Macmillan Publishers Limited 2015 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep16605 ;PMID: 26567894

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17
Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
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Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis

Frontiers in oncology, 2022-06, Vol.12, p.939969-939969 [Peer Reviewed Journal]

Copyright © 2022 Di Giorgio, Marchianò, Marino, Biagioli, Roselli, Bordoni, Bellini, Urbani, Zampella, Distrutti, Donini, Graziosi and Fiorucci 2022 Di Giorgio, Marchianò, Marino, Biagioli, Roselli, Bordoni, Bellini, Urbani, Zampella, Distrutti, Donini, Graziosi and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2022.939969 ;PMID: 35847866

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18
Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists
Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists
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Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists

ACS medicinal chemistry letters, 2019-04, Vol.10 (4), p.504-510 [Peer Reviewed Journal]

Copyright © 2019 American Chemical Society 2019 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/acsmedchemlett.8b00534 ;PMID: 30996787

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19
Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis
Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis
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Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis

PloS one, 2012-01, Vol.7 (1), p.e30443-e30443 [Peer Reviewed Journal]

COPYRIGHT 2012 Public Library of Science ;COPYRIGHT 2012 Public Library of Science ;2012 Renga et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Renga et al. 2012 ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0030443 ;PMID: 22291955

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20
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
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Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma

Frontiers in oncology, 2023-03, Vol.13, p.1140730-1140730 [Peer Reviewed Journal]

Copyright © 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci. ;Copyright © 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci 2023 Di Giorgio, Bellini, Lupia, Massa, Bordoni, Marchianò, Rosselli, Sepe, Rapacciuolo, Moraca, Morretta, Ricci, Urbani, Monti, Biagioli, Distrutti, Catalanotti, Zampella and Fiorucci ;ISSN: 2234-943X ;EISSN: 2234-943X ;DOI: 10.3389/fonc.2023.1140730 ;PMID: 36998446

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