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1
Theonella : A Treasure Trove of Structurally Unique and Biologically Active Sterols
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Theonella : A Treasure Trove of Structurally Unique and Biologically Active Sterols

Marine drugs, 2023-05, Vol.21 (5), p.291 [Peer Reviewed Journal]

2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2023 by the authors. 2023 ;ISSN: 1660-3397 ;EISSN: 1660-3397 ;DOI: 10.3390/md21050291 ;PMID: 37233485

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2
Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1
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Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1

PloS one, 2015-11, Vol.10 (11), p.e0141082-e0141082 [Peer Reviewed Journal]

2015 Renga et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2015 Renga et al 2015 Renga et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0141082 ;PMID: 26539823

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3
The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation
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The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation

PloS one, 2013-01, Vol.8 (1), p.e54472 [Peer Reviewed Journal]

COPYRIGHT 2013 Public Library of Science ;COPYRIGHT 2013 Public Library of Science ;2013 Renga et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2013 Renga et al 2013 Renga et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0054472 ;PMID: 23372731

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4
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction
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Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1092 [Peer Reviewed Journal]

2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 1422-0067 ;ISSN: 1661-6596 ;EISSN: 1422-0067 ;DOI: 10.3390/ijms23031092 ;PMID: 35163018

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5
Development of FXR, PXR and CAR Agonists and Antagonists for Treatment of Liver Disorders
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Development of FXR, PXR and CAR Agonists and Antagonists for Treatment of Liver Disorders

Current topics in medicinal chemistry, 2012-03, Vol.12 (6), p.605-624 [Peer Reviewed Journal]

ISSN: 1568-0266 ;DOI: 10.2174/156802612799436678

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6
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists
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Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists

Scientific reports, 2016-01, Vol.6 (1), p.19008-19008, Article 19008 [Peer Reviewed Journal]

Copyright Nature Publishing Group Jan 2016 ;Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep19008 ;PMID: 26740187

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7
Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition
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Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition

The FASEB journal, 2012-07, Vol.26 (7), p.3021-3031 [Peer Reviewed Journal]

FASEB ;ISSN: 0892-6638 ;EISSN: 1530-6860 ;DOI: 10.1096/fj.11-195701 ;PMID: 22447981

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8
Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism
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Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism

Scientific reports, 2015-11, Vol.5 (1), p.16605-16605, Article 16605 [Peer Reviewed Journal]

Copyright Nature Publishing Group Nov 2015 ;Copyright © 2015, Macmillan Publishers Limited 2015 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep16605 ;PMID: 26567894

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9
Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis
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Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis

PloS one, 2012-01, Vol.7 (1), p.e30443-e30443 [Peer Reviewed Journal]

COPYRIGHT 2012 Public Library of Science ;COPYRIGHT 2012 Public Library of Science ;2012 Renga et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Renga et al. 2012 ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0030443 ;PMID: 22291955

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10
Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease
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Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease

Journal of the American Heart Association, 2023-12, Vol.12 (23), p.e031241-e031241 [Peer Reviewed Journal]

2023 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. ;ISSN: 2047-9980 ;EISSN: 2047-9980 ;DOI: 10.1161/JAHA.123.031241 ;PMID: 37996988

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11
Natural Ligands for Nuclear Receptors: Biology and Potential Therapeutic Applications
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Natural Ligands for Nuclear Receptors: Biology and Potential Therapeutic Applications

Current topics in medicinal chemistry, 2012-03, Vol.12 (6), p.637-669 [Peer Reviewed Journal]

ISSN: 1568-0266 ;DOI: 10.2174/156802612799436650

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12
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands
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Article
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Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands

Scientific reports, 2016-07, Vol.6 (1), p.29320-29320, Article 29320 [Peer Reviewed Journal]

Copyright Nature Publishing Group Jul 2016 ;Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep29320 ;PMID: 27381677

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13
GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
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GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation

Cells (Basel, Switzerland), 2022-04, Vol.11 (7), p.1187 [Peer Reviewed Journal]

2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells11071187 ;PMID: 35406751

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14
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
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Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma

Cells (Basel, Switzerland), 2022-11, Vol.11 (21), p.3482 [Peer Reviewed Journal]

COPYRIGHT 2022 MDPI AG ;2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2022 by the authors. 2022 ;ISSN: 2073-4409 ;EISSN: 2073-4409 ;DOI: 10.3390/cells11213482 ;PMID: 36359879

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15
Oxygenated polyketides from Plakinastrella mamillaris as a new chemotype of PXR agonists
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Oxygenated polyketides from Plakinastrella mamillaris as a new chemotype of PXR agonists

Marine drugs, 2013-07, Vol.11 (7), p.2314-2327 [Peer Reviewed Journal]

Copyright MDPI AG 2013 ;2013 by the authors; licensee MDPI, Basel, Switzerland. 2013 ;ISSN: 1660-3397 ;EISSN: 1660-3397 ;DOI: 10.3390/md11072314 ;PMID: 23820629

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16
Role of nuclear receptors in lipid dysfunction and obesity-related diseases
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Role of nuclear receptors in lipid dysfunction and obesity-related diseases

Drug metabolism and disposition, 2013-01, Vol.41 (1), p.1-11 [Peer Reviewed Journal]

Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics 2013 ;ISSN: 0090-9556 ;EISSN: 1521-009X ;DOI: 10.1124/dmd.112.048694 ;PMID: 23043185

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17
Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis
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Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis

Marine drugs, 2013-12, Vol.12 (1), p.36-53 [Peer Reviewed Journal]

Copyright MDPI AG 2014 ;2013 by the authors; licensee MDPI, Basel, Switzerland. 2013 ;ISSN: 1660-3397 ;EISSN: 1660-3397 ;DOI: 10.3390/md12010036 ;PMID: 24368568

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18
Homophymines B-E and A1-E1, a family of bioactive cyclodepsipeptides from the sponge Homophymia sp
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Homophymines B-E and A1-E1, a family of bioactive cyclodepsipeptides from the sponge Homophymia sp

Organic & biomolecular chemistry, 2009-01, Vol.7 (19), p.4037-44 [Peer Reviewed Journal]

Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 1477-0520 ;EISSN: 1477-0539 ;DOI: 10.1039/b910015f ;PMID: 19763308

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19
Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulation
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Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulation

Marine drugs, 2014-05, Vol.12 (6), p.3091-3115 [Peer Reviewed Journal]

Copyright MDPI AG 2014 ;2014 by the authors; licensee MDPI, Basel, Switzerland. 2014 ;ISSN: 1660-3397 ;EISSN: 1660-3397 ;DOI: 10.3390/md12063091 ;PMID: 24871460

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20
Swinholide J, a potent cytotoxin from the marine sponge Theonella swinhoei
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Swinholide J, a potent cytotoxin from the marine sponge Theonella swinhoei

Marine drugs, 2011-06, Vol.9 (6), p.1133-1141 [Peer Reviewed Journal]

Copyright MDPI AG 2011 ;Distributed under a Creative Commons Attribution 4.0 International License ;2011 by the authors; licensee MDPI, Basel, Switzerland. 2011 ;ISSN: 1660-3397 ;EISSN: 1660-3397 ;DOI: 10.3390/md9061133 ;PMID: 21747751

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