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Nature Open Access
| Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
|---|---|---|---|
| 1 |
Material Type: Article
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Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASHScientific reports, 2023-01, Vol.13 (1), p.1602-1602, Article 1602 [Peer Reviewed Journal]2023. The Author(s). ;The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2023 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-023-28647-4 ;PMID: 36709356Full text available |
| 2 |
Material Type: Article
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Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonistsScientific reports, 2016-01, Vol.6 (1), p.19008-19008, Article 19008 [Peer Reviewed Journal]Copyright Nature Publishing Group Jan 2016 ;Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep19008 ;PMID: 26740187Full text available |
| 3 |
Material Type: Article
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Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonismScientific reports, 2015-11, Vol.5 (1), p.16605-16605, Article 16605 [Peer Reviewed Journal]Copyright Nature Publishing Group Nov 2015 ;Copyright © 2015, Macmillan Publishers Limited 2015 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep16605 ;PMID: 26567894Full text available |
| 4 |
Material Type: Article
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Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligandsScientific reports, 2016-07, Vol.6 (1), p.29320-29320, Article 29320 [Peer Reviewed Journal]Copyright Nature Publishing Group Jul 2016 ;Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep29320 ;PMID: 27381677Full text available |
| 5 |
Material Type: Article
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BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosisScientific reports, 2017-02, Vol.7 (1), p.42801-42801, Article 42801 [Peer Reviewed Journal]Copyright Nature Publishing Group Feb 2017 ;Copyright © 2017, The Author(s) 2017 The Author(s) ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep42801 ;PMID: 28202906Full text available |
| 6 |
Material Type: Article
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Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in miceScientific reports, 2017-10, Vol.7 (1), p.13689-13, Article 13689 [Peer Reviewed Journal]2017. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2017 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-017-13102-y ;PMID: 29057935Full text available |
| 7 |
Material Type: Article
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Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesisScientific reports, 2017-01, Vol.7 (1), p.41055, Article 41055 [Peer Reviewed Journal]Copyright Nature Publishing Group Jan 2017 ;Copyright © 2017, The Author(s) 2017 The Author(s) ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep41055 ;PMID: 28117422Full text available |
| 8 |
Material Type: Article
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Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonistsScientific reports, 2017-02, Vol.7 (1), p.43290-43290, Article 43290 [Peer Reviewed Journal]Copyright © 2017, The Author(s) 2017 The Author(s) ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep43290 ;PMID: 28233865Full text available |
| 9 |
Material Type: Article
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Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1Scientific reports, 2019-02, Vol.9 (1), p.2504-2504, Article 2504 [Peer Reviewed Journal]This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-019-38840-z ;PMID: 30792450Full text available |
| 10 |
Material Type: Article
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Hyodeoxycholic acid derivatives as liver X receptor [alpha] and G-protein-coupled bile acid receptor agonistsScientific reports, 2017-02, Vol.7, p.43290 [Peer Reviewed Journal]Copyright Nature Publishing Group Feb 2017 ;EISSN: 2045-2322 ;DOI: 10.1038/srep43290Full text available |
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