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Material Type: Article
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Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseasesNature genetics, 2018-05, Vol.50 (5), p.693-698 [Peer Reviewed Journal]Copyright Nature Publishing Group May 2018 ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/s41588-018-0099-7 ;PMID: 29686387Full text available |
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Material Type: Article
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Evaluating the potential role of pleiotropy in Mendelian randomization studiesHuman molecular genetics, 2018-08, Vol.27 (R2), p.R195-R208 [Peer Reviewed Journal]The Author(s) 2018. Published by Oxford University Press. 2018 ;ISSN: 0964-6906 ;EISSN: 1460-2083 ;DOI: 10.1093/hmg/ddy163 ;PMID: 29771313Full text available |
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3 |
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Detection and interpretation of shared genetic influences on 42 human traitsNature genetics, 2016-07, Vol.48 (7), p.709-717 [Peer Reviewed Journal]COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Jul 2016 ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/ng.3570 ;PMID: 27182965Full text available |
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Material Type: Article
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Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care SystemsThe American journal of psychiatry, 2019-10, Vol.176 (10), p.846-855 [Peer Reviewed Journal]Copyright © 2019 by the American Psychiatric Association 2019 ;Copyright American Psychiatric Association Oct 1, 2019 ;ISSN: 0002-953X ;EISSN: 1535-7228 ;DOI: 10.1176/appi.ajp.2019.18091085 ;PMID: 31416338Full text available |
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5 |
Material Type: Article
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Pleiotropic Effects of Statins on the Cardiovascular SystemCirculation research, 2017-01, Vol.120 (1), p.229-243 [Peer Reviewed Journal]2017 American Heart Association, Inc. ;Copyright Lippincott Williams & Wilkins Ovid Technologies Jan 6, 2017 ;ISSN: 0009-7330 ;EISSN: 1524-4571 ;DOI: 10.1161/CIRCRESAHA.116.308537 ;PMID: 28057795Full text available |
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6 |
Material Type: Article
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Re: “Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects”American journal of epidemiology, 2015-02, Vol.181 (4), p.290-291 [Peer Reviewed Journal]The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. 2015 ;ISSN: 0002-9262 ;EISSN: 1476-6256 ;DOI: 10.1093/aje/kwv017 ;PMID: 25660081Full text available |
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7 |
Material Type: Article
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Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal EffectsAmerican journal of epidemiology, 2015-02, Vol.181 (4), p.251-260 [Peer Reviewed Journal]The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. 2015 ;The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. ;Copyright Oxford Publishing Limited(England) Feb 15, 2015 ;ISSN: 0002-9262 ;EISSN: 1476-6256 ;DOI: 10.1093/aje/kwu283 ;PMID: 25632051Full text available |
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8 |
Material Type: Article
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Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogensNature genetics, 2014-11, Vol.46 (11), p.1187-1196 [Peer Reviewed Journal]COPYRIGHT 2014 Nature Publishing Group ;COPYRIGHT 2014 Nature Publishing Group ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/ng.3118 ;PMID: 25305756Full text available |
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Material Type: Article
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Combining the strengths of inverse-variance weighting and Egger regression in Mendelian randomization using a mixture of regressions modelPLoS genetics, 2021-11, Vol.17 (11), p.e1009922-e1009922 [Peer Reviewed Journal]COPYRIGHT 2021 Public Library of Science ;2021 Lin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 Lin et al 2021 Lin et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1009922 ;PMID: 34793444Full text available |
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10 |
Material Type: Article
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Beyond the One Gene–One Disease Paradigm: Complex Genetics and Pleiotropy in Inheritable Cardiac DisordersCirculation (New York, N.Y.), 2019-08, Vol.140 (7), p.595-610 [Peer Reviewed Journal]2019 by the American College of Cardiology Foundation and the American Heart Association, Inc. ;ISSN: 0009-7322 ;EISSN: 1524-4539 ;DOI: 10.1161/CIRCULATIONAHA.118.035954 ;PMID: 31403841Full text available |
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11 |
Material Type: Article
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BMI as a Modifiable Risk Factor for Type 2 Diabetes: Refining and Understanding Causal Estimates Using Mendelian RandomizationDiabetes (New York, N.Y.), 2016-10, Vol.65 (10), p.3002-3007 [Peer Reviewed Journal]2016 by the American Diabetes Association. ;Copyright American Diabetes Association Oct 1, 2016 ;ISSN: 0012-1797 ;EISSN: 1939-327X ;DOI: 10.2337/db16-0418 ;PMID: 27402723 ;CODEN: DIAEAZFull text available |
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12 |
Material Type: Article
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Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune functionHuman molecular genetics, 2021-06, Vol.30 (13), p.1259-1270 [Peer Reviewed Journal]The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2021 ;The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ;ISSN: 0964-6906 ;ISSN: 1460-2083 ;EISSN: 1460-2083 ;DOI: 10.1093/hmg/ddab072 ;PMID: 33710309Full text available |
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13 |
Material Type: Article
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Abundant Pleiotropy in Human Complex Diseases and TraitsAmerican journal of human genetics, 2011-11, Vol.89 (5), p.607-618 [Peer Reviewed Journal]2011 The American Society of Human Genetics ;2015 INIST-CNRS ;Copyright © 2011 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved. ;Copyright Cell Press Nov 11, 2011 ;2011 The American Society of Human Genetics. Published by Elsevier Ltd. All right reserved. 2011 The American Society of Human Genetics ;ISSN: 0002-9297 ;EISSN: 1537-6605 ;DOI: 10.1016/j.ajhg.2011.10.004 ;PMID: 22077970 ;CODEN: AJHGAGFull text available |
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14 |
Material Type: Article
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Power analysis of transcriptome-wide association study: Implications for practical protocol choicePLoS genetics, 2021-02, Vol.17 (2), p.e1009405-e1009405 [Peer Reviewed Journal]2021 Cao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 Cao et al 2021 Cao et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1009405 ;PMID: 33635859Full text available |
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Material Type: Article
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The implications of the shared genetics of psychiatric disordersNature medicine, 2016-11, Vol.22 (11), p.1214-1219 [Peer Reviewed Journal]COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Nov 2016 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.4196 ;PMID: 27783064Full text available |
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16 |
Material Type: Article
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Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene lociMolecular psychiatry, 2015-02, Vol.20 (2), p.207-214 [Peer Reviewed Journal]COPYRIGHT 2015 Nature Publishing Group ;Copyright Nature Publishing Group Feb 2015 ;info:eu-repo/semantics/openAccess ;Copyright © 2015 Macmillan Publishers Limited 2015 Macmillan Publishers Limited ;ISSN: 1359-4184 ;ISSN: 1476-5578 ;EISSN: 1476-5578 ;DOI: 10.1038/mp.2013.195 ;PMID: 24468824Full text available |
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17 |
Material Type: Article
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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancerNature genetics, 2020-04, Vol.52 (4), p.408-417 [Peer Reviewed Journal]COPYRIGHT 2020 Nature Publishing Group ;COPYRIGHT 2020 Nature Publishing Group ;Copyright Nature Publishing Group Apr 2020 ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/s41588-020-0590-9 ;PMID: 32203462Full text available |
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18 |
Material Type: Article
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PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statisticsAmerican journal of human genetics, 2021-01, Vol.108 (1), p.36-48 [Peer Reviewed Journal]2020 American Society of Human Genetics ;Copyright © 2020 American Society of Human Genetics. Published by Elsevier Inc. All rights reserved. ;2020 American Society of Human Genetics. 2020 American Society of Human Genetics ;ISSN: 0002-9297 ;EISSN: 1537-6605 ;DOI: 10.1016/j.ajhg.2020.11.017 ;PMID: 33352115Full text available |
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19 |
Material Type: Article
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Transposable Element Exaptation into Regulatory Regions Is Rare, Influenced by Evolutionary Age, and Subject to Pleiotropic ConstraintsMolecular biology and evolution, 2017-11, Vol.34 (11), p.2856-2869 [Peer Reviewed Journal]The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. ;The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2017 ;ISSN: 0737-4038 ;EISSN: 1537-1719 ;DOI: 10.1093/molbev/msx219 ;PMID: 28961735Full text available |
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20 |
Material Type: Article
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The Genomic Landscape and Evolutionary Resolution of Antagonistic Pleiotropy in YeastCell reports (Cambridge), 2012-11, Vol.2 (5), p.1399-1410 [Peer Reviewed Journal]2012 The Authors ;Copyright © 2012 The Authors. Published by Elsevier Inc. All rights reserved. ;2012 Elsevier Inc. All rights reserved. 2012 ;ISSN: 2211-1247 ;EISSN: 2211-1247 ;DOI: 10.1016/j.celrep.2012.09.017 ;PMID: 23103169Full text available |