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Results 1 - 20 of 117  for All Library Resources

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1
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
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Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Nature genetics, 2018-05, Vol.50 (5), p.693-698 [Peer Reviewed Journal]

Copyright Nature Publishing Group May 2018 ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/s41588-018-0099-7 ;PMID: 29686387

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2
Evaluating the potential role of pleiotropy in Mendelian randomization studies
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Evaluating the potential role of pleiotropy in Mendelian randomization studies

Human molecular genetics, 2018-08, Vol.27 (R2), p.R195-R208 [Peer Reviewed Journal]

The Author(s) 2018. Published by Oxford University Press. 2018 ;ISSN: 0964-6906 ;EISSN: 1460-2083 ;DOI: 10.1093/hmg/ddy163 ;PMID: 29771313

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3
Detection and interpretation of shared genetic influences on 42 human traits
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Detection and interpretation of shared genetic influences on 42 human traits

Nature genetics, 2016-07, Vol.48 (7), p.709-717 [Peer Reviewed Journal]

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Jul 2016 ;Distributed under a Creative Commons Attribution 4.0 International License ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/ng.3570 ;PMID: 27182965

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4
Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems
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Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems

The American journal of psychiatry, 2019-10, Vol.176 (10), p.846-855 [Peer Reviewed Journal]

Copyright © 2019 by the American Psychiatric Association 2019 ;Copyright American Psychiatric Association Oct 1, 2019 ;ISSN: 0002-953X ;EISSN: 1535-7228 ;DOI: 10.1176/appi.ajp.2019.18091085 ;PMID: 31416338

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5
Pleiotropic Effects of Statins on the Cardiovascular System
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Pleiotropic Effects of Statins on the Cardiovascular System

Circulation research, 2017-01, Vol.120 (1), p.229-243 [Peer Reviewed Journal]

2017 American Heart Association, Inc. ;Copyright Lippincott Williams & Wilkins Ovid Technologies Jan 6, 2017 ;ISSN: 0009-7330 ;EISSN: 1524-4571 ;DOI: 10.1161/CIRCRESAHA.116.308537 ;PMID: 28057795

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6
Re: “Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects”
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Re: “Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects”

American journal of epidemiology, 2015-02, Vol.181 (4), p.290-291 [Peer Reviewed Journal]

The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. 2015 ;ISSN: 0002-9262 ;EISSN: 1476-6256 ;DOI: 10.1093/aje/kwv017 ;PMID: 25660081

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7
Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects
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Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects

American journal of epidemiology, 2015-02, Vol.181 (4), p.251-260 [Peer Reviewed Journal]

The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. 2015 ;The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. ;Copyright Oxford Publishing Limited(England) Feb 15, 2015 ;ISSN: 0002-9262 ;EISSN: 1476-6256 ;DOI: 10.1093/aje/kwu283 ;PMID: 25632051

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8
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
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Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens

Nature genetics, 2014-11, Vol.46 (11), p.1187-1196 [Peer Reviewed Journal]

COPYRIGHT 2014 Nature Publishing Group ;COPYRIGHT 2014 Nature Publishing Group ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/ng.3118 ;PMID: 25305756

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9
Combining the strengths of inverse-variance weighting and Egger regression in Mendelian randomization using a mixture of regressions model
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Combining the strengths of inverse-variance weighting and Egger regression in Mendelian randomization using a mixture of regressions model

PLoS genetics, 2021-11, Vol.17 (11), p.e1009922-e1009922 [Peer Reviewed Journal]

COPYRIGHT 2021 Public Library of Science ;2021 Lin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 Lin et al 2021 Lin et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1009922 ;PMID: 34793444

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10
Beyond the One Gene–One Disease Paradigm: Complex Genetics and Pleiotropy in Inheritable Cardiac Disorders
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Beyond the One Gene–One Disease Paradigm: Complex Genetics and Pleiotropy in Inheritable Cardiac Disorders

Circulation (New York, N.Y.), 2019-08, Vol.140 (7), p.595-610 [Peer Reviewed Journal]

2019 by the American College of Cardiology Foundation and the American Heart Association, Inc. ;ISSN: 0009-7322 ;EISSN: 1524-4539 ;DOI: 10.1161/CIRCULATIONAHA.118.035954 ;PMID: 31403841

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11
BMI as a Modifiable Risk Factor for Type 2 Diabetes: Refining and Understanding Causal Estimates Using Mendelian Randomization
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BMI as a Modifiable Risk Factor for Type 2 Diabetes: Refining and Understanding Causal Estimates Using Mendelian Randomization

Diabetes (New York, N.Y.), 2016-10, Vol.65 (10), p.3002-3007 [Peer Reviewed Journal]

2016 by the American Diabetes Association. ;Copyright American Diabetes Association Oct 1, 2016 ;ISSN: 0012-1797 ;EISSN: 1939-327X ;DOI: 10.2337/db16-0418 ;PMID: 27402723 ;CODEN: DIAEAZ

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12
Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune function
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Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune function

Human molecular genetics, 2021-06, Vol.30 (13), p.1259-1270 [Peer Reviewed Journal]

The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2021 ;The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com. ;ISSN: 0964-6906 ;ISSN: 1460-2083 ;EISSN: 1460-2083 ;DOI: 10.1093/hmg/ddab072 ;PMID: 33710309

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13
Abundant Pleiotropy in Human Complex Diseases and Traits
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Abundant Pleiotropy in Human Complex Diseases and Traits

American journal of human genetics, 2011-11, Vol.89 (5), p.607-618 [Peer Reviewed Journal]

2011 The American Society of Human Genetics ;2015 INIST-CNRS ;Copyright © 2011 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved. ;Copyright Cell Press Nov 11, 2011 ;2011 The American Society of Human Genetics. Published by Elsevier Ltd. All right reserved. 2011 The American Society of Human Genetics ;ISSN: 0002-9297 ;EISSN: 1537-6605 ;DOI: 10.1016/j.ajhg.2011.10.004 ;PMID: 22077970 ;CODEN: AJHGAG

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14
Power analysis of transcriptome-wide association study: Implications for practical protocol choice
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Power analysis of transcriptome-wide association study: Implications for practical protocol choice

PLoS genetics, 2021-02, Vol.17 (2), p.e1009405-e1009405 [Peer Reviewed Journal]

2021 Cao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 Cao et al 2021 Cao et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1009405 ;PMID: 33635859

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15
The implications of the shared genetics of psychiatric disorders
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The implications of the shared genetics of psychiatric disorders

Nature medicine, 2016-11, Vol.22 (11), p.1214-1219 [Peer Reviewed Journal]

COPYRIGHT 2016 Nature Publishing Group ;COPYRIGHT 2016 Nature Publishing Group ;Copyright Nature Publishing Group Nov 2016 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.4196 ;PMID: 27783064

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16
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci
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Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

Molecular psychiatry, 2015-02, Vol.20 (2), p.207-214 [Peer Reviewed Journal]

COPYRIGHT 2015 Nature Publishing Group ;Copyright Nature Publishing Group Feb 2015 ;info:eu-repo/semantics/openAccess ;Copyright © 2015 Macmillan Publishers Limited 2015 Macmillan Publishers Limited ;ISSN: 1359-4184 ;ISSN: 1476-5578 ;EISSN: 1476-5578 ;DOI: 10.1038/mp.2013.195 ;PMID: 24468824

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17
Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer
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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

Nature genetics, 2020-04, Vol.52 (4), p.408-417 [Peer Reviewed Journal]

COPYRIGHT 2020 Nature Publishing Group ;COPYRIGHT 2020 Nature Publishing Group ;Copyright Nature Publishing Group Apr 2020 ;ISSN: 1061-4036 ;EISSN: 1546-1718 ;DOI: 10.1038/s41588-020-0590-9 ;PMID: 32203462

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18
PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics
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PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics

American journal of human genetics, 2021-01, Vol.108 (1), p.36-48 [Peer Reviewed Journal]

2020 American Society of Human Genetics ;Copyright © 2020 American Society of Human Genetics. Published by Elsevier Inc. All rights reserved. ;2020 American Society of Human Genetics. 2020 American Society of Human Genetics ;ISSN: 0002-9297 ;EISSN: 1537-6605 ;DOI: 10.1016/j.ajhg.2020.11.017 ;PMID: 33352115

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19
Transposable Element Exaptation into Regulatory Regions Is Rare, Influenced by Evolutionary Age, and Subject to Pleiotropic Constraints
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Transposable Element Exaptation into Regulatory Regions Is Rare, Influenced by Evolutionary Age, and Subject to Pleiotropic Constraints

Molecular biology and evolution, 2017-11, Vol.34 (11), p.2856-2869 [Peer Reviewed Journal]

The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. ;The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2017 ;ISSN: 0737-4038 ;EISSN: 1537-1719 ;DOI: 10.1093/molbev/msx219 ;PMID: 28961735

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20
The Genomic Landscape and Evolutionary Resolution of Antagonistic Pleiotropy in Yeast
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The Genomic Landscape and Evolutionary Resolution of Antagonistic Pleiotropy in Yeast

Cell reports (Cambridge), 2012-11, Vol.2 (5), p.1399-1410 [Peer Reviewed Journal]

2012 The Authors ;Copyright © 2012 The Authors. Published by Elsevier Inc. All rights reserved. ;2012 Elsevier Inc. All rights reserved. 2012 ;ISSN: 2211-1247 ;EISSN: 2211-1247 ;DOI: 10.1016/j.celrep.2012.09.017 ;PMID: 23103169

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