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1
Why Most Clinical Research Is Not Useful
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Why Most Clinical Research Is Not Useful

PLoS medicine, 2016-06, Vol.13 (6), p.e1002049-e1002049 [Peer Reviewed Journal]

COPYRIGHT 2016 Public Library of Science ;COPYRIGHT 2016 Public Library of Science ;2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Ioannidis JPA (2016) Why Most Clinical Research Is Not Useful. PLoS Med 13(6): e1002049. doi:10.1371/journal.pmed.1002049 ;2016 John P. A. Ioannidis 2016 John P. A. Ioannidis ;2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Ioannidis JPA (2016) Why Most Clinical Research Is Not Useful. PLoS Med 13(6): e1002049. doi:10.1371/journal.pmed.1002049 ;ISSN: 1549-1676 ;ISSN: 1549-1277 ;EISSN: 1549-1676 ;DOI: 10.1371/journal.pmed.1002049 ;PMID: 27328301

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2
Guidance for developers of health research reporting guidelines
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Guidance for developers of health research reporting guidelines

PLoS medicine, 2010-02, Vol.7 (2), p.e1000217-e1000217 [Peer Reviewed Journal]

COPYRIGHT 2010 Public Library of Science ;COPYRIGHT 2010 Public Library of Science ;Moher et al. 2010 ;2010 Moher et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Moher D, Schulz KF, Simera I, Altman DG (2010) Guidance for Developers of Health Research Reporting Guidelines. PLoS Med 7(2): e1000217. doi:10.1371/journal.pmed.1000217 ;ISSN: 1549-1676 ;ISSN: 1549-1277 ;EISSN: 1549-1676 ;DOI: 10.1371/journal.pmed.1000217 ;PMID: 20169112

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3
Reproducible Research Practices and Transparency across the Biomedical Literature
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Reproducible Research Practices and Transparency across the Biomedical Literature

PLoS biology, 2016-01, Vol.14 (1), p.e1002333-e1002333 [Peer Reviewed Journal]

2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Iqbal SA, Wallach JD, Khoury MJ, Schully SD, Ioannidis JPA (2016) Reproducible Research Practices and Transparency across the Biomedical Literature. PLoS Biol 14(1): e1002333. doi:10.1371/journal.pbio.1002333 ;ISSN: 1545-7885 ;ISSN: 1544-9173 ;EISSN: 1545-7885 ;DOI: 10.1371/journal.pbio.1002333 ;PMID: 26726926

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4
The Profile of Non-Communicable Disease (NCD) research in the Middle East and North Africa (MENA) region: Analyzing the NCD burden, research outputs and international research collaboration
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The Profile of Non-Communicable Disease (NCD) research in the Middle East and North Africa (MENA) region: Analyzing the NCD burden, research outputs and international research collaboration

PloS one, 2020-04, Vol.15 (4), p.e0232077-e0232077 [Peer Reviewed Journal]

COPYRIGHT 2020 Public Library of Science ;2020 Aggarwal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 Aggarwal et al 2020 Aggarwal et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0232077 ;PMID: 32339197

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5
Distinguishing between exploratory and confirmatory preclinical research will improve translation
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Distinguishing between exploratory and confirmatory preclinical research will improve translation

PLoS biology, 2014-05, Vol.12 (5), p.e1001863-e1001863 [Peer Reviewed Journal]

2014 Kimmelman et al 2014 Kimmelman et al ;2014 Kimmelman et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Kimmelman J, Mogil JS, Dirnagl U (2014) Distinguishing between Exploratory and Confirmatory Preclinical Research Will Improve Translation. PLoS Biol 12(5): e1001863. doi:10.1371/journal.pbio.1001863 ;ISSN: 1545-7885 ;ISSN: 1544-9173 ;EISSN: 1545-7885 ;DOI: 10.1371/journal.pbio.1001863 ;PMID: 24844265

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6
Why Having a (Nonfinancial) Interest Is Not a Conflict of Interest
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Why Having a (Nonfinancial) Interest Is Not a Conflict of Interest

PLoS biology, 2016-12, Vol.14 (12), p.e2001221 [Peer Reviewed Journal]

2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Bero LA, Grundy Q (2016) Why Having a (Nonfinancial) Interest Is Not a Conflict of Interest. PLoS Biol 14(12): e2001221. doi:10.1371/journal.pbio.2001221 ;2016 Bero, Grundy 2016 Bero, Grundy ;2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Bero LA, Grundy Q (2016) Why Having a (Nonfinancial) Interest Is Not a Conflict of Interest. PLoS Biol 14(12): e2001221. doi:10.1371/journal.pbio.2001221 ;ISSN: 1545-7885 ;ISSN: 1544-9173 ;EISSN: 1545-7885 ;DOI: 10.1371/journal.pbio.2001221 ;PMID: 28002462

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7
Citation analysis may severely underestimate the impact of clinical research as compared to basic research
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Citation analysis may severely underestimate the impact of clinical research as compared to basic research

PloS one, 2013-04, Vol.8 (4), p.e62395-e62395 [Peer Reviewed Journal]

COPYRIGHT 2013 Public Library of Science ;COPYRIGHT 2013 Public Library of Science ;2013 van Eck et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2013 van Eck et al 2013 van Eck et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0062395 ;PMID: 23638064

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8
The evolving role of preprints in the dissemination of COVID-19 research and their impact on the science communication landscape
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The evolving role of preprints in the dissemination of COVID-19 research and their impact on the science communication landscape

PLoS biology, 2021-04, Vol.19 (4), p.e3000959-e3000959 [Peer Reviewed Journal]

2021 Fraser et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 Fraser et al 2021 Fraser et al ;ISSN: 1545-7885 ;ISSN: 1544-9173 ;EISSN: 1545-7885 ;DOI: 10.1371/journal.pbio.3000959 ;PMID: 33798194

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9
Where there is no health research: what can be done to fill the global gaps in health research?
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Where there is no health research: what can be done to fill the global gaps in health research?

PLoS medicine, 2012-04, Vol.9 (4), p.e1001209-e1001209 [Peer Reviewed Journal]

COPYRIGHT 2012 Public Library of Science ;COPYRIGHT 2012 Public Library of Science ;McKee et al. 2012 ;2012 McKee et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: McKee M, Stuckler D, Basu S (2012) Where There Is No Health Research: What Can Be Done to Fill the Global Gaps in Health Research? PLoS Med 9(4): e1001209. doi:10.1371/journal.pmed.1001209 ;ISSN: 1549-1676 ;ISSN: 1549-1277 ;EISSN: 1549-1676 ;DOI: 10.1371/journal.pmed.1001209 ;PMID: 22545025

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10
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration
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Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration

PLoS medicine, 2012-05, Vol.9 (5), p.e1001216-e1001216 [Peer Reviewed Journal]

COPYRIGHT 2012 Public Library of Science ;COPYRIGHT 2012 Public Library of Science ;2012 Altman et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Altman DG, McShane LM, Sauerbrei W, Taube SE (2012) Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and Elaboration. PLoS Med 9(5): e1001216. doi:10.1371/journal.pmed.1001216 ;Altman et al. 2012 ;ISSN: 1549-1676 ;ISSN: 1549-1277 ;EISSN: 1549-1676 ;DOI: 10.1371/journal.pmed.1001216 ;PMID: 22675273

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11
Facilitating public and patient involvement in basic and preclinical health research
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Article
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Facilitating public and patient involvement in basic and preclinical health research

PloS one, 2019-05, Vol.14 (5), p.e0216600-e0216600 [Peer Reviewed Journal]

COPYRIGHT 2019 Public Library of Science ;COPYRIGHT 2019 Public Library of Science ;2019 Maccarthy et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 Maccarthy et al 2019 Maccarthy et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0216600 ;PMID: 31086377

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12
Reporting and methods in clinical prediction research: a systematic review
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Article
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Reporting and methods in clinical prediction research: a systematic review

PLoS medicine, 2012-05, Vol.9 (5), p.1-12 [Peer Reviewed Journal]

COPYRIGHT 2012 Public Library of Science ;COPYRIGHT 2012 Public Library of Science ;2012 Bouwmeester et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Bouwmeester W, Zuithoff NPA, Mallett S, Geerlings MI, Vergouwe Y, et al. (2012) Reporting and Methods in Clinical Prediction Research: A Systematic Review. PLoS Med 9(5): e1001221. doi:10.1371/journal.pmed.1001221 ;Bouwmeester et al. 2012 ;ISSN: 1549-1676 ;ISSN: 1549-1277 ;EISSN: 1549-1676 ;DOI: 10.1371/journal.pmed.1001221 ;PMID: 22629234

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13
The Global Burden of Journal Peer Review in the Biomedical Literature: Strong Imbalance in the Collective Enterprise
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Article
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The Global Burden of Journal Peer Review in the Biomedical Literature: Strong Imbalance in the Collective Enterprise

PloS one, 2016-11, Vol.11 (11), p.e0166387-e0166387 [Peer Reviewed Journal]

COPYRIGHT 2016 Public Library of Science ;COPYRIGHT 2016 Public Library of Science ;2016 Kovanis et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2016 Kovanis et al 2016 Kovanis et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0166387 ;PMID: 27832157

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14
Will COVID-19 be evidence-based medicine's nemesis?
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Will COVID-19 be evidence-based medicine's nemesis?

PLoS medicine, 2020-06, Vol.17 (6), p.e1003266-e1003266 [Peer Reviewed Journal]

COPYRIGHT 2020 Public Library of Science ;COPYRIGHT 2020 Public Library of Science ;This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication: https://creativecommons.org/publicdomain/zero/1.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1549-1676 ;ISSN: 1549-1277 ;EISSN: 1549-1676 ;DOI: 10.1371/journal.pmed.1003266 ;PMID: 32603323

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15
Ethical challenges of big data in public health
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Ethical challenges of big data in public health

PLoS computational biology, 2015-02, Vol.11 (2), p.e1003904-e1003904 [Peer Reviewed Journal]

COPYRIGHT 2015 Public Library of Science ;COPYRIGHT 2015 Public Library of Science ;2015 Vayena et al 2015 Vayena et al ;2015 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Vayena E, Salathé M, Madoff LC, Brownstein JS (2015) Ethical Challenges of Big Data in Public Health. PLoS Comput Biol 11(2): e1003904. doi:10.1371/journal.pcbi.1003904 ;ISSN: 1553-7358 ;ISSN: 1553-734X ;EISSN: 1553-7358 ;DOI: 10.1371/journal.pcbi.1003904 ;PMID: 25664461

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16
Can animal models of disease reliably inform human studies?
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Can animal models of disease reliably inform human studies?

PLoS medicine, 2010-03, Vol.7 (3), p.e1000245-e1000245 [Peer Reviewed Journal]

COPYRIGHT 2010 Public Library of Science ;COPYRIGHT 2010 Public Library of Science ;van der Worp et al. 2010 ;2010 van der Worp et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: van der Worp HB, Howells DW, Sena ES, Porritt MJ, Rewell S, et al. (2010) Can Animal Models of Disease Reliably Inform Human Studies? PLoS Med 7(3): e1000245. doi:10.1371/journal.pmed.1000245 ;ISSN: 1549-1676 ;ISSN: 1549-1277 ;EISSN: 1549-1676 ;DOI: 10.1371/journal.pmed.1000245 ;PMID: 20361020

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17
Preparedness needs research: How fundamental science and international collaboration accelerated the response to COVID-19
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Preparedness needs research: How fundamental science and international collaboration accelerated the response to COVID-19

PLoS pathogens, 2020-10, Vol.16 (10), p.e1008902-e1008902 [Peer Reviewed Journal]

COPYRIGHT 2020 Public Library of Science ;COPYRIGHT 2020 Public Library of Science ;2020 Kinsella et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 Kinsella et al 2020 Kinsella et al ;ISSN: 1553-7374 ;ISSN: 1553-7366 ;EISSN: 1553-7374 ;DOI: 10.1371/journal.ppat.1008902 ;PMID: 33035262

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18
Lyme disease: call for a "Manhattan Project" to combat the epidemic
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Article
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Lyme disease: call for a "Manhattan Project" to combat the epidemic

PLoS pathogens, 2014-01, Vol.10 (1), p.e1003796-e1003796 [Peer Reviewed Journal]

COPYRIGHT 2014 Public Library of Science ;COPYRIGHT 2014 Public Library of Science ;2014 Stricker, Johnson 2014 Stricker, Johnson ;2014 Stricker, Johnson. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Stricker RB, Johnson L (2014) Lyme Disease: Call for a "Manhattan Project" to Combat the Epidemic. PLoS Pathog 10(1): e1003796. doi:10.1371/journal.ppat.1003796 ;ISSN: 1553-7374 ;ISSN: 1553-7366 ;EISSN: 1553-7374 ;DOI: 10.1371/journal.ppat.1003796 ;PMID: 24391491

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19
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
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Article
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The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

PLoS biology, 2020-07, Vol.18 (7), p.e3000410-e3000410 [Peer Reviewed Journal]

This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication: https://creativecommons.org/publicdomain/zero/1.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1545-7885 ;ISSN: 1544-9173 ;EISSN: 1545-7885 ;DOI: 10.1371/journal.pbio.3000410 ;PMID: 32663219

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20
Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study
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Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study

PLoS medicine, 2016-12, Vol.13 (12), p.e1002162 [Peer Reviewed Journal]

COPYRIGHT 2016 Public Library of Science ;COPYRIGHT 2016 Public Library of Science ;2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Shi J, Hua X, Zhu B, Ravichandran S, Wang M, Nguyen C, et al. (2016) Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study. PLoS Med 13(12): e1002162. doi:10.1371/journal.pmed.1002162 ;2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Shi J, Hua X, Zhu B, Ravichandran S, Wang M, Nguyen C, et al. (2016) Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study. PLoS Med 13(12): e1002162. doi:10.1371/journal.pmed.1002162 ;ISSN: 1549-1676 ;ISSN: 1549-1277 ;EISSN: 1549-1676 ;DOI: 10.1371/journal.pmed.1002162 ;PMID: 27923066

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