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1
Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase
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Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase

Nature communications, 2019-01, Vol.10 (1), p.97-10, Article 97 [Peer Reviewed Journal]

This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-018-07928-x ;PMID: 30626872

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2
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death
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Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

Nature (London), 2019-03, Vol.567 (7746), p.118-122 [Peer Reviewed Journal]

COPYRIGHT 2019 Nature Publishing Group ;Copyright Nature Publishing Group Mar 7, 2019 ;ISSN: 0028-0836 ;EISSN: 1476-4687 ;DOI: 10.1038/s41586-019-0945-5 ;PMID: 30760928

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3
The shape of human squalene epoxidase expands the arsenal against cancer
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The shape of human squalene epoxidase expands the arsenal against cancer

Nature communications, 2019-02, Vol.10 (1), p.888-888, Article 888 [Peer Reviewed Journal]

This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-019-08866-y ;PMID: 30792392

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4
Methyl jasmonate promote protostane triterpenes accumulation by up-regulating the expression of squalene epoxidases in Alisma orientale
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Methyl jasmonate promote protostane triterpenes accumulation by up-regulating the expression of squalene epoxidases in Alisma orientale

Scientific reports, 2019-12, Vol.9 (1), p.18139-13, Article 18139 [Peer Reviewed Journal]

2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-019-54629-6 ;PMID: 31792343

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5
MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer
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MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer

Nature communications, 2021-08, Vol.12 (1), p.5066-5066, Article 5066 [Peer Reviewed Journal]

2021. The Author(s). ;The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2021 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-021-25325-9 ;PMID: 34417456

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6
A widespread alternative squalene epoxidase participates in eukaryote steroid biosynthesis
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A widespread alternative squalene epoxidase participates in eukaryote steroid biosynthesis

Nature microbiology, 2019-02, Vol.4 (2), p.226-233 [Peer Reviewed Journal]

Copyright Nature Publishing Group Feb 2019 ;ISSN: 2058-5276 ;EISSN: 2058-5276 ;DOI: 10.1038/s41564-018-0305-5 ;PMID: 30478288

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7
Squalene synthase predicts poor prognosis in stage I‐III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression
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Squalene synthase predicts poor prognosis in stage I‐III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression

Cancer science, 2022-03, Vol.113 (3), p.971-985 [Peer Reviewed Journal]

2021 The Authors. published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association. ;2021 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association. ;2022. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1347-9032 ;EISSN: 1349-7006 ;DOI: 10.1111/cas.15248 ;PMID: 34939274

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8
Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase
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Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase

eLife, 2023-01, Vol.12 [Peer Reviewed Journal]

2023, Coates et al. ;2023, Coates et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2023, Coates et al 2023 Coates et al ;ISSN: 2050-084X ;EISSN: 2050-084X ;DOI: 10.7554/eLife.82843 ;PMID: 36655986

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9
Enhanced triterpene and phytosterol biosynthesis in Panax ginseng [Panax pseudoginseng] overexpressing squalene synthase gene
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Enhanced triterpene and phytosterol biosynthesis in Panax ginseng [Panax pseudoginseng] overexpressing squalene synthase gene

Plant and cell physiology, 2004-08, Vol.45 (8), p.976-984 [Peer Reviewed Journal]

Copyright Oxford University Press(England) Aug 15, 2004 ;ISSN: 0032-0781 ;EISSN: 1471-9053 ;DOI: 10.1093/pcp/pch126 ;PMID: 15356323

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10
Terbinafine Resistance of Trichophyton Clinical Isolates Caused by Specific Point Mutations in the Squalene Epoxidase Gene
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Terbinafine Resistance of Trichophyton Clinical Isolates Caused by Specific Point Mutations in the Squalene Epoxidase Gene

Antimicrobial agents and chemotherapy, 2017-07, Vol.61 (7) [Peer Reviewed Journal]

Copyright © 2017 American Society for Microbiology. ;ISSN: 0066-4804 ;EISSN: 1098-6596 ;DOI: 10.1128/aac.00115-17 ;PMID: 28416557

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11
Squalene epoxidase‐induced cholesteryl ester accumulation promotes nasopharyngeal carcinoma development by activating PI3K/AKT signaling
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Squalene epoxidase‐induced cholesteryl ester accumulation promotes nasopharyngeal carcinoma development by activating PI3K/AKT signaling

Cancer science, 2020-07, Vol.111 (7), p.2275-2283 [Peer Reviewed Journal]

2020 The Authors. published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association. ;2020 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association. ;2020. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1347-9032 ;EISSN: 1349-7006 ;DOI: 10.1111/cas.14426 ;PMID: 32314495

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12
Mutation in the Squalene Epoxidase Gene of Trichophyton interdigitale and Trichophyton rubrum Associated with Allylamine Resistance
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Mutation in the Squalene Epoxidase Gene of Trichophyton interdigitale and Trichophyton rubrum Associated with Allylamine Resistance

Antimicrobial agents and chemotherapy, 2018-05, Vol.62 (5) [Peer Reviewed Journal]

Copyright © 2018 American Society for Microbiology. ;Copyright © 2018 American Society for Microbiology. 2018 American Society for Microbiology ;ISSN: 0066-4804 ;EISSN: 1098-6596 ;DOI: 10.1128/AAC.02522-17 ;PMID: 29530857

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13
A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition
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A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition

Nature communications, 2019-01, Vol.10 (1), p.96-14, Article 96 [Peer Reviewed Journal]

This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-018-07959-4 ;PMID: 30626880

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14
Accumulation of squalene in a microalga Chlamydomonas reinhardtii by genetic modification of squalene synthase and squalene epoxidase genes
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Accumulation of squalene in a microalga Chlamydomonas reinhardtii by genetic modification of squalene synthase and squalene epoxidase genes

PloS one, 2015-03, Vol.10 (3), p.e0120446-e0120446 [Peer Reviewed Journal]

COPYRIGHT 2015 Public Library of Science ;COPYRIGHT 2015 Public Library of Science ;2015 Kajikawa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2015 Kajikawa et al 2015 Kajikawa et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0120446 ;PMID: 25764133

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15
Squalene epoxidase as a target for manipulation of squalene levels in the yeast Saccharomyces cerevisiae
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Squalene epoxidase as a target for manipulation of squalene levels in the yeast Saccharomyces cerevisiae

FEMS yeast research, 2014-03, Vol.14 (2), p.310-323 [Peer Reviewed Journal]

2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved 2013 ;2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. ;2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved ;ISSN: 1567-1356 ;EISSN: 1567-1364 ;DOI: 10.1111/1567-1364.12107 ;PMID: 24119181

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16
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer
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Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer

Scientific reports, 2016-01, Vol.6 (1), p.19435-19435, Article 19435 [Peer Reviewed Journal]

Copyright Nature Publishing Group Jan 2016 ;Copyright © 2016, Macmillan Publishers Limited 2016 Macmillan Publishers Limited ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/srep19435 ;PMID: 26777065

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17
Squalenoyl-gemcitabine/edelfosine nanoassemblies: Anticancer activity in pediatric cancer cells and pharmacokinetic profile in mice
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Article
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Squalenoyl-gemcitabine/edelfosine nanoassemblies: Anticancer activity in pediatric cancer cells and pharmacokinetic profile in mice

International journal of pharmaceutics, 2020-05, Vol.582 [Peer Reviewed Journal]

Attribution - NonCommercial ;ISSN: 0378-5173 ;EISSN: 1873-3476 ;DOI: 10.1016/j.ijpharm.2020.119345

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18
Rapid detection of terbinafine resistance in Trichophyton species by Amplified refractory mutation system-polymerase chain reaction
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Rapid detection of terbinafine resistance in Trichophyton species by Amplified refractory mutation system-polymerase chain reaction

Scientific reports, 2020-01, Vol.10 (1), p.1297-1297, Article 1297 [Peer Reviewed Journal]

This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2020 ;ISSN: 2045-2322 ;EISSN: 2045-2322 ;DOI: 10.1038/s41598-020-58187-0 ;PMID: 31992797

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19
A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate
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A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (13), p.7150-7158 [Peer Reviewed Journal]

Copyright © 2020 the Author(s). Published by PNAS. ;Copyright National Academy of Sciences Mar 31, 2020 ;Copyright © 2020 the Author(s). Published by PNAS. 2020 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1915923117 ;PMID: 32170014

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20
Squalene and cholesterol in the balance at the ER membrane
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Squalene and cholesterol in the balance at the ER membrane

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (15), p.8228-8230 [Peer Reviewed Journal]

Copyright National Academy of Sciences Apr 14, 2020 ;2020 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.2003388117 ;PMID: 32238557

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