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1
Causal relationships between obesity and the leading causes of death in women and men
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Causal relationships between obesity and the leading causes of death in women and men

PLoS genetics, 2019-10, Vol.15 (10), p.e1008405-e1008405 [Peer Reviewed Journal]

COPYRIGHT 2019 Public Library of Science ;COPYRIGHT 2019 Public Library of Science ;2019 Censin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2019 Censin et al 2019 Censin et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1008405 ;PMID: 31647808

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2
Multimodal CRISPR perturbations of GWAS loci associated with coronary artery disease in vascular endothelial cells
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Multimodal CRISPR perturbations of GWAS loci associated with coronary artery disease in vascular endothelial cells

PLoS genetics, 2023-03, Vol.19 (3), p.e1010680-e1010680 [Peer Reviewed Journal]

Copyright: © 2023 Wünnemann et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. ;COPYRIGHT 2023 Public Library of Science ;2023 Wünnemann et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2023 Wünnemann et al 2023 Wünnemann et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1010680 ;PMID: 36928188

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3
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk
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Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk

PLoS genetics, 2018-10, Vol.14 (10), p.e1007681-e1007681 [Peer Reviewed Journal]

COPYRIGHT 2018 Public Library of Science ;2018 Iyer et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2018 Iyer et al 2018 Iyer et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1007681 ;PMID: 30307970

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4
Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks
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Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks

PLoS genetics, 2013-07, Vol.9 (7), p.e1003588 [Peer Reviewed Journal]

COPYRIGHT 2013 Public Library of Science ;COPYRIGHT 2013 Public Library of Science ;2013 Holdt et al 2013 Holdt et al ;2013 Holdt et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Holdt LM, Hoffmann S, Sass K, Langenberger D, Scholz M, et al. (2013) Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks. PLoS Genet 9(7): e1003588. doi:10.1371/journal.pgen.1003588 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1003588 ;PMID: 23861667

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5
A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach
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A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

PLoS genetics, 2014-07, Vol.10 (7), p.e1004469-e1004469 [Peer Reviewed Journal]

COPYRIGHT 2014 Public Library of Science ;COPYRIGHT 2014 Public Library of Science ;2014 ;2014 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach. PLoS Genet 10(7): e1004469. doi:10.1371/journal.pgen.1004469 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1004469 ;PMID: 25078452

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6
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
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Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

PLoS genetics, 2017-04, Vol.13 (4), p.e1006706 [Peer Reviewed Journal]

COPYRIGHT 2017 Public Library of Science ;COPYRIGHT 2017 Public Library of Science ;2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Folkersen L, Fauman E, Sabater-Lleal M, Strawbridge RJ, Frånberg M, Sennblad B, et al. (2017) Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. PLoS Genet 13(4): e1006706. https://doi.org/10.1371/journal.pgen.1006706 ;2017 Folkersen et al 2017 Folkersen et al ;2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Folkersen L, Fauman E, Sabater-Lleal M, Strawbridge RJ, Frånberg M, Sennblad B, et al. (2017) Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. PLoS Genet 13(4): e1006706. https://doi.org/10.1371/journal.pgen.1006706 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1006706 ;PMID: 28369058

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7
Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease
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Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease

PLoS genetics, 2014-07, Vol.10 (7), p.e1004502-e1004502 [Peer Reviewed Journal]

COPYRIGHT 2014 Public Library of Science ;COPYRIGHT 2014 Public Library of Science ;2014 Mäkinen et al 2014 Mäkinen et al ;2014 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Mäkinen V-P, Civelek M, Meng Q, Zhang B, Zhu J, Levian C, et al. (2014) Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease. PLoS Genet 10(7): e1004502. doi:10.1371/journal.pgen.1004502 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1004502 ;PMID: 25033284

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8
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus
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Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus

PLoS genetics, 2018-11, Vol.14 (11), p.e1007755-e1007755 [Peer Reviewed Journal]

COPYRIGHT 2018 Public Library of Science ;COPYRIGHT 2018 Public Library of Science ;2018 Nanda et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2018 Nanda et al 2018 Nanda et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1007755 ;PMID: 30444878

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9
Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease
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Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease

PLoS genetics, 2015-10, Vol.11 (10), p.e1005622-e1005622 [Peer Reviewed Journal]

COPYRIGHT 2015 Public Library of Science ;COPYRIGHT 2015 Public Library of Science ;2015 Won et al 2015 Won et al ;2015 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Won H-H, Natarajan P, Dobbyn A, Jordan DM, Roussos P, Lage K, et al. (2015) Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease. PLoS Genet 11(10): e1005622. doi:10.1371/journal.pgen.1005622 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1005622 ;PMID: 26509271

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10
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap
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Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap

PLoS genetics, 2015-05, Vol.11 (5), p.e1005155-e1005155 [Peer Reviewed Journal]

COPYRIGHT 2015 Public Library of Science ;COPYRIGHT 2015 Public Library of Science ;2015 Nurnberg et al 2015 Nurnberg et al ;2015 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Nurnberg ST, Cheng K, Raiesdana A, Kundu R, Miller CL, Kim JB, et al. (2015) Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap. PLoS Genet 11(5): e1005155. doi:10.1371/journal.pgen.1005155 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1005155 ;PMID: 26020946

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11
Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy
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Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy

PLoS genetics, 2017-06, Vol.13 (6), p.e1006328-e1006328 [Peer Reviewed Journal]

COPYRIGHT 2017 Public Library of Science ;COPYRIGHT 2017 Public Library of Science ;2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Byars SG, Huang QQ, Gray L-A, Bakshi A, Ripatti S, Abraham G, et al. (2017) Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy. PLoS Genet 13(6): e1006328. https://doi.org/10.1371/journal.pgen.1006328 ;2017 Byars et al 2017 Byars et al ;2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Byars SG, Huang QQ, Gray L-A, Bakshi A, Ripatti S, Abraham G, et al. (2017) Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy. PLoS Genet 13(6): e1006328. https://doi.org/10.1371/journal.pgen.1006328 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1006328 ;PMID: 28640878

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12
The Contribution of GWAS Loci in Familial Dyslipidemias
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The Contribution of GWAS Loci in Familial Dyslipidemias

PLoS genetics, 2016-05, Vol.12 (5), p.e1006078-e1006078 [Peer Reviewed Journal]

COPYRIGHT 2016 Public Library of Science ;COPYRIGHT 2016 Public Library of Science ;2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Ripatti P, Rämö JT, Söderlund S, Surakka I, Matikainen N, Pirinen M, et al. (2016) The Contribution of GWAS Loci in Familial Dyslipidemias. PLoS Genet 12(5): e1006078. doi:10.1371/journal.pgen.1006078 ;2016 Ripatti et al 2016 Ripatti et al ;2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Ripatti P, Rämö JT, Söderlund S, Surakka I, Matikainen N, Pirinen M, et al. (2016) The Contribution of GWAS Loci in Familial Dyslipidemias. PLoS Genet 12(5): e1006078. doi:10.1371/journal.pgen.1006078 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1006078 ;PMID: 27227539

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13
A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease
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A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

PLoS genetics, 2020-04, Vol.16 (4), p.e1008629 [Peer Reviewed Journal]

2020 Emdin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2020 Emdin et al 2020 Emdin et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1008629 ;PMID: 32282858

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14
RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function
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RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function

PLoS genetics, 2013-02, Vol.9 (2), p.e1003338-e1003338 [Peer Reviewed Journal]

COPYRIGHT 2013 Public Library of Science ;COPYRIGHT 2013 Public Library of Science ;2013 Blattmann et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Blattmann P, Schuberth C, Pepperkok R, Runz H (2013) RNAi-Based Functional Profiling of Loci from Blood Lipid Genome-Wide Association Studies Identifies Genes with Cholesterol-Regulatory Function. PLoS Genet 9(2): e1003338. doi:10.1371/journal.pgen.1003338 ;2013 Blattmann et al 2013 Blattmann et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1003338 ;PMID: 23468663

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15
Identifying systematic heterogeneity patterns in genetic association meta-analysis studies
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Identifying systematic heterogeneity patterns in genetic association meta-analysis studies

PLoS genetics, 2017-05, Vol.13 (5), p.e1006755-e1006755 [Peer Reviewed Journal]

COPYRIGHT 2017 Public Library of Science ;COPYRIGHT 2017 Public Library of Science ;2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Magosi LE, Goel A, Hopewell JC, Farrall M, on behalf of the CARDIoGRAMplusC4D Consortium (2017) Identifying systematic heterogeneity patterns in genetic association meta-analysis studies. PLoS Genet 13(5): e1006755. https://doi.org/10.1371/journal.pgen.1006755 ;2017 Magosi et al 2017 Magosi et al ;2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Magosi LE, Goel A, Hopewell JC, Farrall M, on behalf of the CARDIoGRAMplusC4D Consortium (2017) Identifying systematic heterogeneity patterns in genetic association meta-analysis studies. PLoS Genet 13(5): e1006755. https://doi.org/10.1371/journal.pgen.1006755 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1006755 ;PMID: 28459806

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16
De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders
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De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders

PLoS genetics, 2018-12, Vol.14 (12), p.e1007822-e1007822 [Peer Reviewed Journal]

COPYRIGHT 2018 Public Library of Science ;COPYRIGHT 2018 Public Library of Science ;2018 Qi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2018 Qi et al 2018 Qi et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1007822 ;PMID: 30532227

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17
The impact of age on genetic risk for common diseases
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The impact of age on genetic risk for common diseases

PLoS genetics, 2021-08, Vol.17 (8), p.e1009723 [Peer Reviewed Journal]

COPYRIGHT 2021 Public Library of Science ;2021 Jiang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2021 Jiang et al 2021 Jiang et al ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1009723 ;PMID: 34437535

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18
Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association Studies
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Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association Studies

PLoS genetics, 2016-04, Vol.12 (4), p.e1005947-e1005947 [Peer Reviewed Journal]

COPYRIGHT 2016 Public Library of Science ;COPYRIGHT 2016 Public Library of Science ;2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Lu Q, Powles RL, Wang Q, He BJ, Zhao H (2016) Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association Studies. PLoS Genet 12(4): e1005947. doi:10.1371/journal.pgen.1005947 ;2016 Lu et al 2016 Lu et al ;2016 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Lu Q, Powles RL, Wang Q, He BJ, Zhao H (2016) Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association Studies. PLoS Genet 12(4): e1005947. doi:10.1371/journal.pgen.1005947 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1005947 ;PMID: 27058395

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19
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum
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Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum

PLoS genetics, 2008-11, Vol.4 (11), p.e1000282-e1000282 [Peer Reviewed Journal]

COPYRIGHT 2008 Public Library of Science ;Gieger et al. 2008 ;2008 Gieger et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Gieger C, Geistlinger L, Altmaier E, Hrabé de Angelis M, Kronenberg F, et al. (2008) Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum. PLoS Genet 4(11): e1000282. doi:10.1371/journal.pgen.1000282 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1000282 ;PMID: 19043545

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20
Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) study
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Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) study

PLoS genetics, 2009-12, Vol.5 (12), p.e1000754-e1000754 [Peer Reviewed Journal]

Hägg et al. 2009 ;2009 Hägg et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Hägg S, Skogsberg J, Lundström J, Noori P, Nilsson R, et al. (2009) Multi-Organ Expression Profiling Uncovers a Gene Module in Coronary Artery Disease Involving Transendothelial Migration of Leukocytes and LIM Domain Binding 2: The Stockholm Atherosclerosis Gene Expression (STAGE) Study. PLoS Genet 5(12): e1000754. doi:10.1371/journal.pgen.1000754 ;ISSN: 1553-7404 ;ISSN: 1553-7390 ;EISSN: 1553-7404 ;DOI: 10.1371/journal.pgen.1000754 ;PMID: 19997623

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