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1
Unraveling the therapeutic potential of the Hedgehog pathway in cancer
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Unraveling the therapeutic potential of the Hedgehog pathway in cancer

Nature medicine, 2013-11, Vol.19 (11), p.1410-1422 [Peer Reviewed Journal]

COPYRIGHT 2013 Nature Publishing Group ;COPYRIGHT 2013 Nature Publishing Group ;Copyright Nature Publishing Group Nov 2013 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.3389 ;PMID: 24202394

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2
AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations
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AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations

Cancer discovery, 2017-05, Vol.7 (5), p.478-493

2017 American Association for Cancer Research. ;ISSN: 2159-8274 ;EISSN: 2159-8290 ;DOI: 10.1158/2159-8290.cd-16-1034 ;PMID: 28193778

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3
MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis
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MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis

Cell reports (Cambridge), 2016-04, Vol.15 (3), p.574-587 [Peer Reviewed Journal]

2016 The Authors ;Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved. ;ISSN: 2211-1247 ;EISSN: 2211-1247 ;DOI: 10.1016/j.celrep.2016.03.043 ;PMID: 27068473

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4
PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers
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PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers

Cancer research (Chicago, Ill.), 2009-05, Vol.69 (10), p.4286-4293 [Peer Reviewed Journal]

ISSN: 0008-5472 ;EISSN: 1538-7445 ;DOI: 10.1158/0008-5472.CAN-08-4765 ;PMID: 19401449

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5
Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor
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Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor

Molecular cancer therapeutics, 2012-02, Vol.11 (2), p.317-328 [Peer Reviewed Journal]

ISSN: 1535-7163 ;EISSN: 1538-8514 ;DOI: 10.1158/1535-7163.mct-11-0474 ;PMID: 22188813

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6
Acquired On-Target Clinical Resistance Validates FGFR4 as a Driver of Hepatocellular Carcinoma
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Acquired On-Target Clinical Resistance Validates FGFR4 as a Driver of Hepatocellular Carcinoma

Cancer discovery, 2019-12, Vol.9 (12), p.1686-1695

2019 American Association for Cancer Research. ;ISSN: 2159-8274 ;EISSN: 2159-8290 ;DOI: 10.1158/2159-8290.cd-19-0367 ;PMID: 31575540

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7
IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition
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IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition

Blood, 2015-01, Vol.125 (2), p.296-303 [Peer Reviewed Journal]

2015 American Society of Hematology ;2015 by The American Society of Hematology. ;2015 by The American Society of Hematology 2015 ;ISSN: 0006-4971 ;EISSN: 1528-0020 ;DOI: 10.1182/blood-2013-10-533604 ;PMID: 25398940

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8
A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition
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A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition

Nature communications, 2019-01, Vol.10 (1), p.96-14, Article 96 [Peer Reviewed Journal]

This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-018-07959-4 ;PMID: 30626880

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9
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities
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Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities

Nature medicine, 2013-11, Vol.19 (11), p.1518-1523 [Peer Reviewed Journal]

COPYRIGHT 2013 Nature Publishing Group ;COPYRIGHT 2013 Nature Publishing Group ;Copyright Nature Publishing Group Nov 2013 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.3328 ;PMID: 24076665

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10
ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis
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ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (29), p.9088-9093 [Peer Reviewed Journal]

Volumes 1–89 and 106–112, copyright as a collective work only; author(s) retains copyright to individual articles ;Copyright National Academy of Sciences Jul 21, 2015 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1510757112 ;PMID: 26150517

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11
Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway
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Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

Nature medicine, 2010-12, Vol.16 (12), p.1429-1433 [Peer Reviewed Journal]

COPYRIGHT 2010 Nature Publishing Group ;COPYRIGHT 2010 Nature Publishing Group ;Copyright Nature Publishing Group Dec 2010 ;2010 Nature America, Inc. All rights reserved. 2010 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.2251 ;PMID: 21076395

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12
Hedgehog pathway activation in chronic myeloid leukemia: A promise for a novel combination therapeutic approach?
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Hedgehog pathway activation in chronic myeloid leukemia: A promise for a novel combination therapeutic approach?

Cell cycle (Georgetown, Tex.), 2010-09, Vol.9 (17), p.3449-3456 [Peer Reviewed Journal]

Copyright © 2010 Landes Bioscience 2010 ;ISSN: 1538-4101 ;EISSN: 1551-4005 ;DOI: 10.4161/cc.9.17.12945

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13
Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition
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Article
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Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition

PloS one, 2014-12, Vol.9 (12), p.e115144-e115144 [Peer Reviewed Journal]

COPYRIGHT 2014 Public Library of Science ;COPYRIGHT 2014 Public Library of Science ;2014 Ulanet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2014 Ulanet et al 2014 Ulanet et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0115144 ;PMID: 25502225

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14
Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDH
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Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDH

Cell reports (Cambridge), 2016-10, Vol.17 (3), p.876-890 [Peer Reviewed Journal]

2016 The Author(s) ;Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved. ;ISSN: 2211-1247 ;EISSN: 2211-1247 ;DOI: 10.1016/j.celrep.2016.09.052 ;PMID: 27732861

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15
A mouse model of a human congenital disorder of glycosylation caused by loss of PMM2
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Article
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A mouse model of a human congenital disorder of glycosylation caused by loss of PMM2

Human molecular genetics, 2016-06, Vol.25 (11), p.2182-2193 [Peer Reviewed Journal]

The Author 2016. Published by Oxford University Press. ;The Author 2016. Published by Oxford University Press. 2016 ;ISSN: 0964-6906 ;EISSN: 1460-2083 ;DOI: 10.1093/hmg/ddw085 ;PMID: 27053713

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16
Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist
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Article
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Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

ACS medicinal chemistry letters, 2010-06, Vol.1 (3), p.130-134 [Peer Reviewed Journal]

Copyright © 2010 American Chemical Society ;Copyright © 2010 American Chemical Society 2010 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/ml1000307 ;PMID: 24900187

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17
The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells
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The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells

Cancer research (Chicago, Ill.), 2010-07, Vol.70 (13), p.5528-5538 [Peer Reviewed Journal]

2015 INIST-CNRS ;Copyright 2010 AACR. ;ISSN: 0008-5472 ;EISSN: 1538-7445 ;DOI: 10.1158/0008-5472.can-09-4229 ;PMID: 20530672 ;CODEN: CNREA8

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18
Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma
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Article
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Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma

Gastro hep advances, 2023, Vol.2 (3), p.307-321 [Peer Reviewed Journal]

2023 ;ISSN: 2772-5723 ;EISSN: 2772-5723 ;DOI: 10.1016/j.gastha.2022.11.004

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19
PK1/EG-VEGF induces monocyte differentiation and activation
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Article
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PK1/EG-VEGF induces monocyte differentiation and activation

Journal of leukocyte biology, 2005-08, Vol.78 (2), p.426-434 [Peer Reviewed Journal]

2005 Society for Leukocyte Biology ;ISSN: 0741-5400 ;EISSN: 1938-3673 ;DOI: 10.1189/jlb.0205061 ;PMID: 15908459

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20
Participation of Rip2 in Lipopolysaccharide Signaling Is Independent of Its Kinase Activity
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Article
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Participation of Rip2 in Lipopolysaccharide Signaling Is Independent of Its Kinase Activity

The Journal of biological chemistry, 2005-04, Vol.280 (16), p.16278-16283 [Peer Reviewed Journal]

2005 © 2005 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M410114200 ;PMID: 15691841

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