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1 |
Material Type: Article
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Unraveling the therapeutic potential of the Hedgehog pathway in cancerNature medicine, 2013-11, Vol.19 (11), p.1410-1422 [Peer Reviewed Journal]COPYRIGHT 2013 Nature Publishing Group ;COPYRIGHT 2013 Nature Publishing Group ;Copyright Nature Publishing Group Nov 2013 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.3389 ;PMID: 24202394Full text available |
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Material Type: Article
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AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 MutationsCancer discovery, 2017-05, Vol.7 (5), p.478-4932017 American Association for Cancer Research. ;ISSN: 2159-8274 ;EISSN: 2159-8290 ;DOI: 10.1158/2159-8290.cd-16-1034 ;PMID: 28193778Full text available |
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3 |
Material Type: Article
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MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 AxisCell reports (Cambridge), 2016-04, Vol.15 (3), p.574-587 [Peer Reviewed Journal]2016 The Authors ;Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved. ;ISSN: 2211-1247 ;EISSN: 2211-1247 ;DOI: 10.1016/j.celrep.2016.03.043 ;PMID: 27068473Full text available |
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4 |
Material Type: Article
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PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancersCancer research (Chicago, Ill.), 2009-05, Vol.69 (10), p.4286-4293 [Peer Reviewed Journal]ISSN: 0008-5472 ;EISSN: 1538-7445 ;DOI: 10.1158/0008-5472.CAN-08-4765 ;PMID: 19401449Full text available |
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5 |
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Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitorMolecular cancer therapeutics, 2012-02, Vol.11 (2), p.317-328 [Peer Reviewed Journal]ISSN: 1535-7163 ;EISSN: 1538-8514 ;DOI: 10.1158/1535-7163.mct-11-0474 ;PMID: 22188813Full text available |
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6 |
Material Type: Article
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Acquired On-Target Clinical Resistance Validates FGFR4 as a Driver of Hepatocellular CarcinomaCancer discovery, 2019-12, Vol.9 (12), p.1686-16952019 American Association for Cancer Research. ;ISSN: 2159-8274 ;EISSN: 2159-8290 ;DOI: 10.1158/2159-8290.cd-19-0367 ;PMID: 31575540Full text available |
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7 |
Material Type: Article
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IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibitionBlood, 2015-01, Vol.125 (2), p.296-303 [Peer Reviewed Journal]2015 American Society of Hematology ;2015 by The American Society of Hematology. ;2015 by The American Society of Hematology 2015 ;ISSN: 0006-4971 ;EISSN: 1528-0020 ;DOI: 10.1182/blood-2013-10-533604 ;PMID: 25398940Full text available |
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8 |
Material Type: Article
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A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibitionNature communications, 2019-01, Vol.10 (1), p.96-14, Article 96 [Peer Reviewed Journal]This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2019 ;ISSN: 2041-1723 ;EISSN: 2041-1723 ;DOI: 10.1038/s41467-018-07959-4 ;PMID: 30626880Full text available |
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Material Type: Article
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Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunitiesNature medicine, 2013-11, Vol.19 (11), p.1518-1523 [Peer Reviewed Journal]COPYRIGHT 2013 Nature Publishing Group ;COPYRIGHT 2013 Nature Publishing Group ;Copyright Nature Publishing Group Nov 2013 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.3328 ;PMID: 24076665Full text available |
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10 |
Material Type: Article
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ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesisProceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (29), p.9088-9093 [Peer Reviewed Journal]Volumes 1–89 and 106–112, copyright as a collective work only; author(s) retains copyright to individual articles ;Copyright National Academy of Sciences Jul 21, 2015 ;ISSN: 0027-8424 ;EISSN: 1091-6490 ;DOI: 10.1073/pnas.1510757112 ;PMID: 26150517Full text available |
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11 |
Material Type: Article
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Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathwayNature medicine, 2010-12, Vol.16 (12), p.1429-1433 [Peer Reviewed Journal]COPYRIGHT 2010 Nature Publishing Group ;COPYRIGHT 2010 Nature Publishing Group ;Copyright Nature Publishing Group Dec 2010 ;2010 Nature America, Inc. All rights reserved. 2010 ;ISSN: 1078-8956 ;EISSN: 1546-170X ;DOI: 10.1038/nm.2251 ;PMID: 21076395Full text available |
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12 |
Material Type: Article
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Hedgehog pathway activation in chronic myeloid leukemia: A promise for a novel combination therapeutic approach?Cell cycle (Georgetown, Tex.), 2010-09, Vol.9 (17), p.3449-3456 [Peer Reviewed Journal]Copyright © 2010 Landes Bioscience 2010 ;ISSN: 1538-4101 ;EISSN: 1551-4005 ;DOI: 10.4161/cc.9.17.12945Full text available |
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13 |
Material Type: Article
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Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibitionPloS one, 2014-12, Vol.9 (12), p.e115144-e115144 [Peer Reviewed Journal]COPYRIGHT 2014 Public Library of Science ;COPYRIGHT 2014 Public Library of Science ;2014 Ulanet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2014 Ulanet et al 2014 Ulanet et al ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0115144 ;PMID: 25502225Full text available |
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14 |
Material Type: Article
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Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDHCell reports (Cambridge), 2016-10, Vol.17 (3), p.876-890 [Peer Reviewed Journal]2016 The Author(s) ;Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved. ;ISSN: 2211-1247 ;EISSN: 2211-1247 ;DOI: 10.1016/j.celrep.2016.09.052 ;PMID: 27732861Full text available |
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15 |
Material Type: Article
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A mouse model of a human congenital disorder of glycosylation caused by loss of PMM2Human molecular genetics, 2016-06, Vol.25 (11), p.2182-2193 [Peer Reviewed Journal]The Author 2016. Published by Oxford University Press. ;The Author 2016. Published by Oxford University Press. 2016 ;ISSN: 0964-6906 ;EISSN: 1460-2083 ;DOI: 10.1093/hmg/ddw085 ;PMID: 27053713Full text available |
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Material Type: Article
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Discovery of NVP-LDE225, a Potent and Selective Smoothened AntagonistACS medicinal chemistry letters, 2010-06, Vol.1 (3), p.130-134 [Peer Reviewed Journal]Copyright © 2010 American Chemical Society ;Copyright © 2010 American Chemical Society 2010 American Chemical Society ;ISSN: 1948-5875 ;EISSN: 1948-5875 ;DOI: 10.1021/ml1000307 ;PMID: 24900187Full text available |
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17 |
Material Type: Article
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The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma CellsCancer research (Chicago, Ill.), 2010-07, Vol.70 (13), p.5528-5538 [Peer Reviewed Journal]2015 INIST-CNRS ;Copyright 2010 AACR. ;ISSN: 0008-5472 ;EISSN: 1538-7445 ;DOI: 10.1158/0008-5472.can-09-4229 ;PMID: 20530672 ;CODEN: CNREA8Full text available |
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18 |
Material Type: Article
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Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar CarcinomaGastro hep advances, 2023, Vol.2 (3), p.307-321 [Peer Reviewed Journal]2023 ;ISSN: 2772-5723 ;EISSN: 2772-5723 ;DOI: 10.1016/j.gastha.2022.11.004Full text available |
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19 |
Material Type: Article
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PK1/EG-VEGF induces monocyte differentiation and activationJournal of leukocyte biology, 2005-08, Vol.78 (2), p.426-434 [Peer Reviewed Journal]2005 Society for Leukocyte Biology ;ISSN: 0741-5400 ;EISSN: 1938-3673 ;DOI: 10.1189/jlb.0205061 ;PMID: 15908459Full text available |
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Material Type: Article
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Participation of Rip2 in Lipopolysaccharide Signaling Is Independent of Its Kinase ActivityThe Journal of biological chemistry, 2005-04, Vol.280 (16), p.16278-16283 [Peer Reviewed Journal]2005 © 2005 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. ;ISSN: 0021-9258 ;EISSN: 1083-351X ;DOI: 10.1074/jbc.M410114200 ;PMID: 15691841Full text available |