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The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

Blood, 2009-07, Vol.114 (5), p.937-951 [Peer Reviewed Journal]

2009 American Society of Hematology ;2009 INIST-CNRS ;ISSN: 0006-4971 ;ISSN: 1528-0020 ;EISSN: 1528-0020 ;DOI: 10.1182/blood-2009-03-209262 ;PMID: 19357394

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Title:
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
Author: Vardiman, James W. ; Thiele, Jüergen ; Arber, Daniel A. ; Brunning, Richard D. ; Borowitz, Michael J. ; Porwit, Anna ; Harris, Nancy Lee ; Le Beau, Michelle M. ; Hellström-Lindberg, Eva ; Tefferi, Ayalew ; Bloomfield, Clara D.
Subjects: Acute Disease ; Biological and medical sciences ; Bone Marrow Examination - standards ; Cell Count ; Cell Lineage ; Chromosome Aberrations ; Eosinophilia - classification ; Hematologic and hematopoietic diseases ; Hematologic Neoplasms - classification ; Humans ; Leukemia - classification ; Leukemia - diagnosis ; Leukemia - genetics ; Leukemia - pathology ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Mastocytosis, Systemic - classification ; Medical sciences ; Medicin och hälsovetenskap ; Mutation ; Myelodysplastic Syndromes - classification ; Myelodysplastic Syndromes - diagnosis ; Myelodysplastic Syndromes - genetics ; Myelodysplastic Syndromes - pathology ; Myelodysplastic-Myeloproliferative Diseases - classification ; Myelodysplastic-Myeloproliferative Diseases - diagnosis ; Myelodysplastic-Myeloproliferative Diseases - genetics ; Myelodysplastic-Myeloproliferative Diseases - pathology ; Myeloproliferative Disorders - classification ; Myeloproliferative Disorders - diagnosis ; Myeloproliferative Disorders - genetics ; Myeloproliferative Disorders - pathology ; Neoplastic Stem Cells - pathology ; Preleukemia - classification ; Terminology as Topic ; World Health Organization
Is Part Of: Blood, 2009-07, Vol.114 (5), p.937-951
Description: Recently the World Health Organization (WHO), in collaboration with the European Association for Haematopathology and the Society for Hematopathology, published a revised and updated edition of the WHO Classification of Tumors of the Hematopoietic and Lymphoid Tissues. The 4th edition of the WHO classification incorporates new information that has emerged from scientific and clinical studies in the interval since the publication of the 3rd edition in 2001, and includes new criteria for the recognition of some previously described neoplasms as well as clarification and refinement of the defining criteria for others. It also adds entities—some defined principally by genetic features—that have only recently been characterized. In this paper, the classification of myeloid neoplasms and acute leukemia is highlighted with the aim of familiarizing hematologists, clinical scientists, and hematopathologists not only with the major changes in the classification but also with the rationale for those changes.
Publisher: Washington, DC: Elsevier Inc
Language: English
Identifier: ISSN: 0006-4971
ISSN: 1528-0020
EISSN: 1528-0020
DOI: 10.1182/blood-2009-03-209262
PMID: 19357394
Source: GFMER Free Medical Journals
MEDLINE
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The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

2009 American Society of Hematology ;2009 INIST-CNRS ;ISSN: 0006-4971 ;ISSN: 1528-0020 ;EISSN: 1528-0020 ;DOI: 10.1182/blood-2009-03-209262 ;PMID: 19357394

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