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Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions?

Environmental health perspectives, 2012-09, Vol.120 (9), p.1221-1229 [Peer Reviewed Journal]

2015 INIST-CNRS ;COPYRIGHT 2012 National Institute of Environmental Health Sciences ;COPYRIGHT 2012 National Institute of Environmental Health Sciences ;Copyright National Institute of Environmental Health Sciences Sep 2012 ;2012 ;ISSN: 0091-6765 ;EISSN: 1552-9924 ;DOI: 10.1289/ehp.1104477 ;PMID: 22647657 ;CODEN: EVHPAZ

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Title:
Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions?
Author: Boxall, Alistair B.A. ; Rudd, Murray A. ; Brooks, Bryan W. ; Caldwell, Daniel J. ; Choi, Kyungho ; Hickmann, Silke ; Innes, Elizabeth ; Ostapyk, Kim ; Staveley, Jane P. ; Verslycke, Tim ; Ankley, Gerald T. ; Beazley, Karen F. ; Belanger, Scott E. ; Berninger, Jason P. ; Carriquiriborde, Pedro ; Coors, Anja ; DeLeo, Paul C. ; Dyer, Scott D. ; Ericson, Jon F. ; Gagné, François ; Giesy, John P. ; Gouin, Todd ; Hallstrom, Lars ; Karlsson, Maja V. ; Larsson, D. G. Joakim ; Lazorchak, James M. ; Mastrocco, Frank ; McLaughlin, Alison ; McMaster, Mark E. ; Meyerhoff, Roger D. ; Moore, Roberta ; Parrott, Joanne L. ; Snape, Jason R. ; Murray-Smith, Richard ; Servos, Mark R. ; Sibley, Paul K. ; Straub, Jürg Oliver ; Szabo, Nora D. ; Topp, Edward ; Tetreault, Gerald R. ; Trudeau, Vance L. ; Van Der Kraak, Glen
Subjects: agricultural soils ; Antibiotic resistance ; aquatic environment ; Biological and medical sciences ; Business ; Chemical hazards ; Communities ; Complications and side effects ; conservation ; Drug Resistance, Microbial - drug effects ; Drug-Related Side Effects and Adverse Reactions ; Ecological risk assessment ; ecotoxicity ; Ecotoxicology ; Environment. Living conditions ; Environmental aspects ; Environmental conservation ; Environmental Exposure ; Environmental health ; Environmental Monitoring ; exposure assessment ; fish ; Health ; Health and beauty aids ; Health and wellness ; health effects ; Health products ; Health Sciences ; Household Products - analysis ; Household Products - toxicity ; Humans ; Hygiene products ; Hälsovetenskaper ; Lists ; Management ; Medical sciences ; personal care products ; Pharmaceutical preparations ; Pharmaceutical Preparations - analysis ; Pharmaceutical Preparations - metabolism ; Pharmaceuticals ; promoting human health ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Research - organization & administration ; Review ; Reviews ; Risk ; Risk Assessment ; Risk management ; to-cradle stewardship ; Toiletries ; Toxicology ; transformation products ; veterinary medicines ; Wastewater treatment ; water ; Workshops ; Workshops (Educational programs)
Is Part Of: Environmental health perspectives, 2012-09, Vol.120 (9), p.1221-1229
Description: Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data Sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed Initially, were solicited from academic government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data Synthesis: The top 20 priority questions fell into seven categories: a) prioritization or substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.
Publisher: Research Triangle Park, NC: National Institute of Environmental Health Sciences
Language: English
Identifier: ISSN: 0091-6765
EISSN: 1552-9924
DOI: 10.1289/ehp.1104477
PMID: 22647657
CODEN: EVHPAZ
Source: U.S. Government Documents
MEDLINE
PubMed Central
ProQuest Central
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Pharmaceuticals and Personal Care Products in the Environment: What Are the Big Questions?

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