Language:

Roles of Regulatory T Cells in Tissue Pathophysiology and Metabolism

Cell metabolism, 2020-01, Vol.31 (1), p.18-25 [Peer Reviewed Journal]

2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;ISSN: 1550-4131 ;EISSN: 1932-7420 ;DOI: 10.1016/j.cmet.2019.09.010 ;PMID: 31607562

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Roles of Regulatory T Cells in Tissue Pathophysiology and Metabolism
Author: Campbell, Clarissa ; Rudensky, Alexander
Subjects: Adaptive Immunity ; Animals ; Autoimmunity ; Forkhead Transcription Factors - metabolism ; Homeostasis - immunology ; Humans ; Inflammation - immunology ; Inflammation - metabolism ; Inflammation - physiopathology ; metabolism ; Regeneration - immunology ; Regeneration - physiology ; regulatory T cells ; T-Lymphocytes, Regulatory - immunology ; tissue homeostasis
Is Part Of: Cell metabolism, 2020-01, Vol.31 (1), p.18-25
Description: Regulatory T (Treg) cells expressing the X-chromosome-encoded transcription factor Foxp3 represent a specialized immunosuppressive lineage with a well-recognized, essential function in preventing fatal autoimmunity and inflammation. Recent studies revealed that Treg cells can also exert systemic effects on metabolism and partake in tissue repair, suggesting a dual role for these cells in serving and protecting tissues. Here, we review multiple means by which Treg cells support tissue function and organismal homeostasis. Campbell and Rudensky review the roles of regulatory T cells in organismal homeostasis and metabolic health, with a focus on the major immunological and non-immunological mechanisms by which these specialized suppressive cells of the adaptive immune system support the function of various tissues and organs.
Publisher: United States: Elsevier Inc
Language: English
Identifier: ISSN: 1550-4131
EISSN: 1932-7420
DOI: 10.1016/j.cmet.2019.09.010
PMID: 31607562
Source: Cell Press Free Archives
MEDLINE

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Roles of Regulatory T Cells in Tissue Pathophysiology and Metabolism

2019 Elsevier Inc. ;Copyright © 2019 Elsevier Inc. All rights reserved. ;ISSN: 1550-4131 ;EISSN: 1932-7420 ;DOI: 10.1016/j.cmet.2019.09.010 ;PMID: 31607562

Searching Remote Databases, Please Wait