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New Insights into the Role of Trace Elements in IBD

BioMed research international, 2018-01, Vol.2018, p.1813047-9 [Peer Reviewed Journal]

Copyright © 2018 Georgiana-Emmanuela Gîlcă-Blanariu et al. ;COPYRIGHT 2018 Hindawi Limited ;Copyright © 2018 Georgiana-Emmanuela Gîlcă-Blanariu et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0 ;Copyright © 2018 Georgiana-Emmanuela Gîlcă-Blanariu et al. 2018 ;ISSN: 2314-6133 ;EISSN: 2314-6141 ;DOI: 10.1155/2018/1813047 ;PMID: 30258848

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Title:
New Insights into the Role of Trace Elements in IBD
Author: Gîlcă-Blanariu, Georgiana-Emmanuela ; Diaconescu, Smaranda ; Ciocoiu, Manuela ; Ștefănescu, Gabriela
Flora, Swaran J. S. ; Swaran J S Flora
Subjects: Antioxidants ; Cytokines ; Dendritic cells ; Evolution ; Gastrointestinal diseases ; Humans ; Immune response ; Inflammation ; Inflammatory bowel disease ; Inflammatory Bowel Diseases ; Inflammatory response ; Intestine ; Malnutrition ; Melatonin ; Microbiota ; Microbiota (Symbiotic organisms) ; Micronutrients ; Morbidity ; Mucosal immunity ; Oxidative stress ; Pathogenesis ; Physiological aspects ; Review ; Rodents ; Selenium ; Trace Elements ; Zinc
Is Part Of: BioMed research international, 2018-01, Vol.2018, p.1813047-9
Description: Micronutrient deficiencies are common in inflammatory bowel disease and have clinical impact, being both a sign of complicated disease and a cause of morbidity. The involved systemic inflammatory response is responsible for altering the concentration of a wide range of trace elements in the serum, including zinc and selenium. This review summarizes recent advances and evidence-based knowledge regarding the impact of selenium and zinc on oxidative stress and microbiota changes in IBD patients. Getting new insight into the impact of malnutrition, particularly on the micronutrients’ impact on the development, composition, and metabolism of microbiota, as well as the influence of oxidative stress and the mucosal immune response, could help in implementing new management strategies for IBD patients, with focus on a more integrated approach.
Publisher: United States: Hindawi
Language: English
Identifier: ISSN: 2314-6133
EISSN: 2314-6141
DOI: 10.1155/2018/1813047
PMID: 30258848
Source: MEDLINE
PubMed Central
ProQuest Central

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New Insights into the Role of Trace Elements in IBD

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