Language:

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

Cell metabolism, 2013-04, Vol.17 (4), p.491-506 [Peer Reviewed Journal]

2013 Elsevier Inc. ;Copyright © 2013 Elsevier Inc. All rights reserved. ;ISSN: 1550-4131 ;EISSN: 1932-7420 ;DOI: 10.1016/j.cmet.2013.03.002 ;PMID: 23562075

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
Author: Liesa, Marc ; Shirihai, Orian S.
Subjects: Adenosine Triphosphate - metabolism ; Adipose Tissue, Brown - metabolism ; Aging ; Animals ; Diabetes Mellitus, Type 2 - metabolism ; Diabetes Mellitus, Type 2 - pathology ; Energy Metabolism - physiology ; Humans ; Insulin-Secreting Cells - metabolism ; Mitochondria - metabolism ; Mitochondrial Dynamics - physiology ; Muscle, Skeletal - metabolism ; Obesity - metabolism ; Obesity - pathology
Is Part Of: Cell metabolism, 2013-04, Vol.17 (4), p.491-506
Description: Mitochondrial fusion, fission, and mitophagy form an essential axis of mitochondrial quality control. However, quality control might not be the only task carried out by mitochondrial dynamics. Recent studies link mitochondrial dynamics to the balance between energy demand and nutrient supply, suggesting changes in mitochondrial architecture as a mechanism for bioenergetic adaptation to metabolic demands. By favoring either connected or fragmented architectures, mitochondrial dynamics regulates bioenergetic efficiency and energy expenditure. Placement of bioenergetic adaptation and quality control as competing tasks of mitochondrial dynamics might provide a new mechanism, linking excess nutrient environment to progressive mitochondrial dysfunction, common to age-related diseases.
Publisher: United States: Elsevier Inc
Language: English
Identifier: ISSN: 1550-4131
EISSN: 1932-7420
DOI: 10.1016/j.cmet.2013.03.002
PMID: 23562075
Source: Cell Press Free Archives
MEDLINE

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

2013 Elsevier Inc. ;Copyright © 2013 Elsevier Inc. All rights reserved. ;ISSN: 1550-4131 ;EISSN: 1932-7420 ;DOI: 10.1016/j.cmet.2013.03.002 ;PMID: 23562075

Searching Remote Databases, Please Wait